SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CR5_X_PNTX94_0 (PROTEIN S100-B)	4zqd	ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	3 / 3	PHE B 244 CYH B 257 PHE B 254	0X3 B 401 (-4.3A) 0X3 B 401 ( 4.8A) 0X3 B 401 (-4.4A)	1.10A	3cr5X-4zqdB: undetectable	3cr5X-4zqdB: 14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RZV_A_032A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	4zqd	ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	4 / 5	ILE B 223 VAL B 101 PHE B 134 CYH B 195	None	1.27A	4rzvA-4zqdB: undetectable	4rzvA-4zqdB: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UDA_A_DEXA1985_2 (MINERALOCORTICOID RECEPTOR)	4zqd	ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	4 / 6	LEU B 59 LEU B 111 PHE B 110 THR B 66	None	1.06A	4udaA-4zqdB: undetectable	4udaA-4zqdB: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZPH_A_PRLA501_0 (ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1)	4zqd	ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1 (Mus musculus)	5 / 7	GLN B 306 TRP B 318 LEU B 344 SER B 345 GLU B 348	None	0.58A	4zphA-4zqdB: 11.1 4zphB-4zqdB: 28.7	4zphA-4zqdB: 28.54 4zphB-4zqdB: 100.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CR5_X_PNTX94_0","PROTEIN S100-B","4zqd","ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1","Mus musculus",3,"PHE B 244;CYH B 257;PHE B 254","0X3 B 401 (-4.3A);0X3 B 401 ( 4.8A);0X3 B 401 (-4.4A)","1.10A","3cr5X-4zqdB:undetectable","3cr5X-4zqdB:14.37"],["4RZV_A_032A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","4zqd","ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1","Mus musculus",4,"ILE B 223;VAL B 101;PHE B 134;CYH B 195","None","1.27A","4rzvA-4zqdB:undetectable","4rzvA-4zqdB:19.67"],["4UDA_A_DEXA1985_2","MINERALOCORTICOID RECEPTOR","4zqd","ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1","Mus musculus",4,"LEU B  59;LEU B 111;PHE B 110;THR B  66","None","1.06A","4udaA-4zqdB:undetectable","4udaA-4zqdB:19.06"],["4ZPH_A_PRLA501_0","ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR;ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1","4zqd","ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1","Mus musculus",5,"GLN B 306;TRP B 318;LEU B 344;SER B 345;GLU B 348","None","0.58A","4zphA-4zqdB:11.1;4zphB-4zqdB:28.7","4zphA-4zqdB:28.54;4zphB-4zqdB:100.00"]]