SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zqg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 7 MET A 279
PRO A 151
ALA A 286
ALA A 126
 NAD  A 501 (-3.8A)
None
None
NAD  A 501 (-3.1A)
 1.01A 1k5qA-4zqgA:
undetectable
1k5qB-4zqgA:
undetectable		 1k5qA-4zqgA:
19.66
1k5qB-4zqgA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 10 ALA A 142
THR A 141
VAL A 138
ALA A 116
THR A 113
 None
 1.17A 1r55A-4zqgA:
2.4		 1r55A-4zqgA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 LEU A 244
ALA A 238
LEU A 186
ARG A 325
ILE A 167
 None
 1.07A 1s9pA-4zqgA:
undetectable		 1s9pA-4zqgA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 11 LEU A 137
GLY A 118
ALA A 117
ILE A  89
VAL A 138
 None
 0.85A 1t7jA-4zqgA:
undetectable		 1t7jA-4zqgA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 6 ALA A 238
GLU A 237
ILE A 236
LEU A 186
 None
None
NHE  A 505 ( 4.5A)
None
 0.98A 1xvaA-4zqgA:
3.2
1xvaB-4zqgA:
3.5		 1xvaA-4zqgA:
22.72
1xvaB-4zqgA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 11 VAL A 101
ILE A  17
GLY A  18
ILE A  24
LEU A 287
 None
NAD  A 501 (-3.9A)
None
None
None
 1.01A 1z11A-4zqgA:
undetectable		 1z11A-4zqgA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 11 VAL A 101
ILE A  17
GLY A  18
ILE A  24
LEU A 287
 None
NAD  A 501 (-3.9A)
None
None
None
 0.97A 1z11B-4zqgA:
undetectable		 1z11B-4zqgA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 10 VAL A 101
ILE A  17
GLY A  18
ILE A  24
LEU A 287
 None
NAD  A 501 (-3.9A)
None
None
None
 0.98A 1z11C-4zqgA:
undetectable		 1z11C-4zqgA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 10 VAL A 101
ILE A  17
GLY A  18
ILE A  24
LEU A 287
 None
NAD  A 501 (-3.9A)
None
None
None
 1.06A 1z11D-4zqgA:
undetectable		 1z11D-4zqgA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 LEU A 137
GLY A 118
ALA A 117
ILE A  89
VAL A 138
 None
 0.89A 2ieoB-4zqgA:
undetectable		 2ieoB-4zqgA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 8 THR A  60
THR A  38
LYS A  45
ASP A  44
 None
 1.20A 2kotB-4zqgA:
undetectable		 2kotB-4zqgA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 9 GLY A 118
LEU A 114
THR A 141
ALA A 142
LEU A 125
 None
 1.26A 2npnA-4zqgA:
undetectable		 2npnA-4zqgA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 GLY A  87
GLY A  12
GLY A  39
THR A  14
ILE A  10
 None
NAD  A 501 (-3.3A)
NAD  A 501 (-3.6A)
NAD  A 501 (-3.6A)
None
 0.88A 2pxcA-4zqgA:
undetectable		 2pxcA-4zqgA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 GLY A  87
GLY A  12
GLY A  39
THR A  14
ILE A  10
 None
NAD  A 501 (-3.3A)
NAD  A 501 (-3.6A)
NAD  A 501 (-3.6A)
None
 0.88A 2wa2A-4zqgA:
3.8		 2wa2A-4zqgA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 GLY A  87
GLY A  12
GLY A  39
THR A  14
ILE A  10
 None
NAD  A 501 (-3.3A)
NAD  A 501 (-3.6A)
NAD  A 501 (-3.6A)
None
 0.92A 2wa2B-4zqgA:
3.7		 2wa2B-4zqgA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 5 VAL A 259
GLN A 161
PHE A 270
ARG A 292
 None
 1.39A 3bjwB-4zqgA:
2.4		 3bjwB-4zqgA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 4 LEU A  37
ASP A  98
VAL A 101
THR A  21
 None
 0.95A 3cyxB-4zqgA:
undetectable		 3cyxB-4zqgA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 LEU A  22
GLY A  12
GLY A  18
THR A  38
LEU A  88
 None
NAD  A 501 (-3.3A)
None
None
None
 1.11A 3dh0B-4zqgA:
3.0		 3dh0B-4zqgA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 GLY A  87
GLY A  12
GLY A  39
THR A  14
ILE A  10
 None
NAD  A 501 (-3.3A)
NAD  A 501 (-3.6A)
NAD  A 501 (-3.6A)
None
 0.88A 3eluA-4zqgA:
undetectable		 3eluA-4zqgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 GLY A  87
GLY A  12
GLY A  39
THR A  14
ILE A  10
 None
NAD  A 501 (-3.3A)
NAD  A 501 (-3.6A)
NAD  A 501 (-3.6A)
None
 0.88A 3embA-4zqgA:
2.9		 3embA-4zqgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 7 GLY A  12
GLY A  15
THR A  21
ALA A 103
 NAD  A 501 (-3.3A)
NAD  A 501 (-3.4A)
None
NAD  A 501 (-4.4A)
 0.84A 3fpjB-4zqgA:
4.3		 3fpjB-4zqgA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 GLY A  87
GLY A  12
GLY A  39
THR A  14
ILE A  10
 None
NAD  A 501 (-3.3A)
NAD  A 501 (-3.6A)
NAD  A 501 (-3.6A)
None
 0.91A 3gczA-4zqgA:
3.3		 3gczA-4zqgA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		6 / 12 SER A 111
LEU A 391
ALA A 116
VAL A 138
GLY A 135
ALA A 134
 None
 1.40A 3ln1D-4zqgA:
undetectable		 3ln1D-4zqgA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 10 LEU A 137
GLY A 118
ALA A 117
ILE A  89
VAL A 138
 None
 0.91A 3nu9B-4zqgA:
undetectable		 3nu9B-4zqgA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 9 PRO A 164
ILE A 181
ILE A 174
VAL A 263
ILE A 159
 None
 1.17A 3p4wB-4zqgA:
undetectable		 3p4wB-4zqgA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 8 ILE A 152
VAL A 101
THR A  21
ILE A  24
 None
 0.80A 3p4wC-4zqgA:
undetectable		 3p4wC-4zqgA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 10 PRO A 164
ILE A 181
ILE A 174
VAL A 263
ILE A 159
 None
 1.17A 3p4wD-4zqgA:
undetectable		 3p4wD-4zqgA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 10 PRO A 164
ILE A 181
ILE A 174
VAL A 263
ILE A 159
 None
 1.17A 3p4wE-4zqgA:
undetectable		 3p4wE-4zqgA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 8 SER A 225
HIS A 212
GLU A 234
GLU A 237
 FOM  A 503 (-2.5A)
FOM  A 503 ( 4.6A)
MG  A 502 ( 2.7A)
None
 1.14A 3sg9B-4zqgA:
undetectable		 3sg9B-4zqgA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 LEU A 137
GLY A 118
ALA A 117
ILE A  89
VAL A 138
 None
 0.76A 3ucbA-4zqgA:
undetectable		 3ucbA-4zqgA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 LEU A 137
GLY A 118
ALA A 117
ILE A  89
VAL A 138
 None
 0.74A 3ucbB-4zqgA:
undetectable		 3ucbB-4zqgA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 7 LEU A 287
THR A  21
ILE A  10
THR A  99
 None
 0.89A 4eq4A-4zqgA:
undetectable		 4eq4A-4zqgA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 7 LEU A 287
THR A  21
ILE A  10
THR A  99
 None
 0.90A 4eqlB-4zqgA:
undetectable		 4eqlB-4zqgA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_C_MTXC604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 LEU A 110
ASP A 394
LEU A 391
SER A 112
THR A 340
 None
 1.26A 4q0dC-4zqgA:
undetectable		 4q0dC-4zqgA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_D_MTXD604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 LEU A 110
ASP A 394
LEU A 391
SER A 112
THR A 340
 None
 1.27A 4q0dD-4zqgA:
undetectable		 4q0dD-4zqgA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 4 ASN A 127
SER A 112
ALA A 102
VAL A 101
 NAD  A 501 (-4.4A)
None
None
None
 1.18A 4x1kC-4zqgA:
1.8		 4x1kC-4zqgA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 5 LEU A 350
ALA A 345
ASN A 342
ILE A 359
 None
 1.20A 4y03B-4zqgA:
undetectable		 4y03B-4zqgA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 9 LYS A 143
LEU A 244
LEU A 163
ILE A 181
ALA A 173
 None
 1.46A 4z69A-4zqgA:
2.3		 4z69A-4zqgA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 ALA A  23
GLY A  18
SER A  16
GLY A 296
LEU A 287
 None
None
NAD  A 501 (-3.6A)
None
None
 0.98A 5gwxA-4zqgA:
3.6		 5gwxA-4zqgA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 GLY A  87
GLY A  12
GLY A  39
THR A  14
ILE A  10
 None
NAD  A 501 (-3.3A)
NAD  A 501 (-3.6A)
NAD  A 501 (-3.6A)
None
 0.92A 5ikmA-4zqgA:
3.0		 5ikmA-4zqgA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_B_Z80B401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 9 ILE A  17
VAL A 105
ASN A 230
GLU A 234
ILE A 221
 NAD  A 501 (-3.9A)
NAD  A 501 (-4.2A)
FOM  A 503 (-3.3A)
MG  A 502 ( 2.7A)
NAD  A 501 ( 3.8A)
 1.41A 5lg3B-4zqgA:
0.9		 5lg3B-4zqgA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		4 / 8 ILE A 152
VAL A 101
THR A  21
ILE A  24
 None
 0.90A 5mzrE-4zqgA:
undetectable		 5mzrE-4zqgA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 GLY A  87
GLY A  12
GLY A  39
THR A  14
ILE A  10
 None
NAD  A 501 (-3.3A)
NAD  A 501 (-3.6A)
NAD  A 501 (-3.6A)
None
 0.98A 5njvD-4zqgA:
undetectable		 5njvD-4zqgA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Moraxella
catarrhalis) 		5 / 12 GLY A  87
GLY A  12
GLY A  39
THR A  14
ILE A  10
 None
NAD  A 501 (-3.3A)
NAD  A 501 (-3.6A)
NAD  A 501 (-3.6A)
None
 0.93A 5wz2C-4zqgA:
3.2		 5wz2C-4zqgA:
20.61