SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zqu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 4zqu CDII TOXIN
(Salmonella
enterica) 		4 / 5 LEU B 168
GLY B  51
ILE B 129
ILE B 131
 None
 0.82A 2q9rA-4zquB:
undetectable		 2q9rA-4zquB:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 4zqu CDII TOXIN
(Salmonella
enterica) 		3 / 3 SER B 119
ASP B 121
ASN B  30
 None
 0.92A 3lsfB-4zquB:
undetectable
3lsfE-4zquB:
undetectable		 3lsfB-4zquB:
21.97
3lsfE-4zquB:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 4zqu CDII TOXIN
(Salmonella
enterica) 		3 / 3 ASP B 121
ASN B  30
SER B 119
 None
 0.95A 3lsfB-4zquB:
undetectable
3lsfE-4zquB:
undetectable		 3lsfB-4zquB:
21.97
3lsfE-4zquB:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4zqu CDIA-CT TOXIN,
CONSERVED DOMAIN
PROTEIN
CDII TOXIN
(Yersinia
pseudotuberculos
is;
Salmonella
enterica) 		5 / 12 ALA B  67
GLY A 187
SER A 188
ASP B  86
LEU B  82
 None
 1.45A 3ou6D-4zquB:
undetectable		 3ou6D-4zquB:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4zqu CDIA-CT TOXIN,
CONSERVED DOMAIN
PROTEIN
(Yersinia
pseudotuberculos
is) 		4 / 5 TYR A 199
THR A 217
LEU A 213
THR A 292
 None
 1.46A 4mbsB-4zquA:
undetectable		 4mbsB-4zquA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 4zqu CDII TOXIN
(Salmonella
enterica) 		4 / 8 GLY B  51
GLY B 165
LEU B 168
GLU B 163
 None
 0.74A 5vw5A-4zquB:
undetectable		 5vw5A-4zquB:
18.41