SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zr0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 313
VAL A 233
TRP A 236
 None
 0.94A 1c4dA-4zr0A:
undetectable
1c4dB-4zr0A:
undetectable		 1c4dA-4zr0A:
3.19
1c4dB-4zr0A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 249
HIS A 345
HIS A 349
HIS A 272
 ZN  A 402 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
 0.91A 1e9yB-4zr0A:
undetectable		 1e9yB-4zr0A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 8 PHE A 357
HIS A 272
HIS A 271
HIS A 268
HIS A 348
 None
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.3A)
 1.45A 1ei6D-4zr0A:
undetectable		 1ei6D-4zr0A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 326
HIS A 345
HIS A 348
TYR A 350
PRO A 175
 ZN  A 401 (-3.4A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
None
None
 1.36A 1ituA-4zr0A:
undetectable		 1ituA-4zr0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 326
HIS A 345
HIS A 348
TYR A 350
PRO A 175
 ZN  A 401 (-3.4A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
None
None
 1.38A 1ituB-4zr0A:
undetectable		 1ituB-4zr0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.70A 1rjoA-4zr0A:
undetectable		 1rjoA-4zr0A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 268
HIS A 249
HIS A 244
 ZN  A 402 (-3.5A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.7A)
 0.67A 1rkyA-4zr0A:
undetectable		 1rkyA-4zr0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.66A 1rkyA-4zr0A:
undetectable		 1rkyA-4zr0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 372
ASP A 365
GLY A 358
HIS A 249
HIS A 244
 None
None
None
ZN  A 402 (-3.2A)
ZN  A 402 (-3.7A)
 1.43A 1s9aA-4zr0A:
undetectable		 1s9aA-4zr0A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 372
ASP A 365
GLY A 358
HIS A 249
HIS A 244
 None
None
None
ZN  A 402 (-3.2A)
ZN  A 402 (-3.7A)
 1.45A 1s9aB-4zr0A:
undetectable		 1s9aB-4zr0A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 1w2zA-4zr0A:
undetectable		 1w2zA-4zr0A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.66A 1w2zB-4zr0A:
undetectable		 1w2zB-4zr0A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.70A 1w2zC-4zr0A:
undetectable		 1w2zC-4zr0A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.66A 1w2zD-4zr0A:
undetectable		 1w2zD-4zr0A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 122
ILE A 158
LEU A 154
GLY A 269
ILE A 172
 None
 1.36A 2ogyB-4zr0A:
undetectable		 2ogyB-4zr0A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 2oqeA-4zr0A:
undetectable		 2oqeA-4zr0A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 2oqeB-4zr0A:
undetectable		 2oqeB-4zr0A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 2oqeC-4zr0A:
undetectable		 2oqeC-4zr0A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 2oqeD-4zr0A:
undetectable		 2oqeD-4zr0A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.71A 2oqeF-4zr0A:
undetectable		 2oqeF-4zr0A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.69A 2w0qA-4zr0A:
undetectable		 2w0qA-4zr0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.69A 2w0qB-4zr0A:
undetectable		 2w0qB-4zr0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 244
HIS A 249
HIS A 268
HIS A 348
 ZN  A 402 (-3.7A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.3A)
 0.77A 2wkoA-4zr0A:
undetectable		 2wkoA-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 272
HIS A 271
HIS A 268
HIS A 349
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.2A)
 0.91A 2wkoA-4zr0A:
undetectable		 2wkoA-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 326
HIS A 330
HIS A 345
HIS A 271
 ZN  A 401 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.2A)
 0.79A 2wkoA-4zr0A:
undetectable		 2wkoA-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 330
HIS A 326
HIS A 271
HIS A 345
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.04A 2wkoA-4zr0A:
undetectable		 2wkoA-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 345
HIS A 330
HIS A 349
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.4A)
 0.94A 2wkoA-4zr0A:
undetectable		 2wkoA-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 349
HIS A 348
HIS A 345
HIS A 272
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.4A)
 0.80A 2wkoA-4zr0A:
undetectable		 2wkoA-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 244
HIS A 249
HIS A 268
HIS A 348
 ZN  A 402 (-3.7A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.3A)
 0.80A 2wkoF-4zr0A:
undetectable		 2wkoF-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 272
HIS A 271
HIS A 268
HIS A 349
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.2A)
 0.97A 2wkoF-4zr0A:
undetectable		 2wkoF-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 326
HIS A 330
HIS A 345
HIS A 271
 ZN  A 401 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.2A)
 0.85A 2wkoF-4zr0A:
undetectable		 2wkoF-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 345
HIS A 330
HIS A 349
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.4A)
 0.96A 2wkoF-4zr0A:
undetectable		 2wkoF-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 345
HIS A 348
VAL A 359
HIS A 244
 ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
None
ZN  A 402 (-3.7A)
 1.00A 2wkoF-4zr0A:
undetectable		 2wkoF-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 348
HIS A 345
VAL A 359
HIS A 244
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.5A)
None
ZN  A 402 (-3.7A)
 0.92A 2wkoF-4zr0A:
undetectable		 2wkoF-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 349
HIS A 348
HIS A 345
HIS A 272
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.4A)
 0.85A 2wkoF-4zr0A:
undetectable		 2wkoF-4zr0A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 122
ILE A 158
LEU A 154
GLY A 269
ILE A 172
 None
 1.34A 2ycjA-4zr0A:
undetectable		 2ycjA-4zr0A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 345
HIS A 330
HIS A 326
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
 0.72A 3hiiB-4zr0A:
undetectable		 3hiiB-4zr0A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NJZ_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 349
HIS A 330
HIS A 345
HIS A 244
LEU A 281
 ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.7A)
None
 1.24A 3njzA-4zr0A:
undetectable		 3njzA-4zr0A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 244
HIS A 348
HIS A 268
ASP A 251
 ZN  A 402 (-3.7A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.5A)
None
 1.16A 3nvcA-4zr0A:
undetectable		 3nvcA-4zr0A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 348
HIS A 272
HIS A 244
ASP A 251
 ZN  A 402 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.7A)
None
 1.23A 3nvcA-4zr0A:
undetectable		 3nvcA-4zr0A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 348
HIS A 272
HIS A 249
 ZN  A 402 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.2A)
 0.54A 3qpkA-4zr0A:
undetectable		 3qpkA-4zr0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 249
HIS A 348
HIS A 272
 ZN  A 402 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.4A)
 0.60A 3qpkB-4zr0A:
undetectable		 3qpkB-4zr0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 272
HIS A 249
HIS A 348
 ZN  A 402 (-3.4A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.3A)
 0.60A 3qpkB-4zr0A:
undetectable		 3qpkB-4zr0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 348
HIS A 272
HIS A 249
 ZN  A 402 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.2A)
 0.52A 3qpkB-4zr0A:
undetectable		 3qpkB-4zr0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 10 TYR A 344
HIS A 268
HIS A 249
HIS A 272
HIS A 345
 None
ZN  A 402 (-3.5A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.5A)
 1.22A 4c1dB-4zr0A:
undetectable		 4c1dB-4zr0A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 272
HIS A 268
HIS A 349
HIS A 348
 ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
 1.05A 4ef3A-4zr0A:
undetectable		 4ef3A-4zr0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 349
HIS A 345
HIS A 272
HIS A 271
 ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
 1.09A 4ef3A-4zr0A:
undetectable		 4ef3A-4zr0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 272
HIS A 271
HIS A 345
HIS A 349
HIS A 330
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
 1.26A 4ef3A-4zr0A:
undetectable		 4ef3A-4zr0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 272
HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.19A 4ef3A-4zr0A:
undetectable		 4ef3A-4zr0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 349
HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 1.25A 4ef3A-4zr0A:
undetectable		 4ef3A-4zr0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 249
HIS A 345
HIS A 349
HIS A 272
 ZN  A 402 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
 0.87A 4h9mA-4zr0A:
undetectable		 4h9mA-4zr0A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 7 HIS A 345
HIS A 326
HIS A 268
HIS A 244
VAL A 359
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
None
 1.08A 4p6sA-4zr0A:
undetectable		 4p6sA-4zr0A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 7 HIS A 268
HIS A 244
HIS A 345
HIS A 326
 ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
 0.94A 4p6sB-4zr0A:
undetectable		 4p6sB-4zr0A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 7 HIS A 345
HIS A 326
HIS A 268
HIS A 244
VAL A 359
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
None
 1.09A 4p6sB-4zr0A:
undetectable		 4p6sB-4zr0A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 243
TYR A 322
TYR A 319
PHE A 288
LEU A 291
 None
 1.33A 5cymA-4zr0A:
undetectable		 5cymA-4zr0A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 243
TYR A 322
TYR A 319
PHE A 288
LEU A 291
 None
 1.32A 5cyqA-4zr0A:
undetectable		 5cyqA-4zr0A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 ALA A 135
PRO A 175
GLY A 356
LEU A 126
 None
 0.91A 5eslA-4zr0A:
undetectable		 5eslA-4zr0A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 281
CYH A 325
HIS A 331
LEU A 329
 None
 1.49A 5hrqD-4zr0A:
undetectable
5hrqG-4zr0A:
undetectable
5hrqH-4zr0A:
undetectable		 5hrqD-4zr0A:
9.23
5hrqG-4zr0A:
4.90
5hrqH-4zr0A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 7 HIS A 345
HIS A 326
HIS A 268
HIS A 244
VAL A 359
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
None
 1.08A 5i3aA-4zr0A:
undetectable		 5i3aA-4zr0A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 7 HIS A 345
HIS A 326
HIS A 268
HIS A 244
VAL A 359
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
None
 1.06A 5i3aB-4zr0A:
undetectable		 5i3aB-4zr0A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 7 HIS A 345
HIS A 326
HIS A 268
HIS A 244
VAL A 359
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
None
 1.10A 5i3bA-4zr0A:
undetectable		 5i3bA-4zr0A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 345
HIS A 326
HIS A 244
VAL A 359
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 402 (-3.7A)
None
 1.03A 5i3bB-4zr0A:
undetectable		 5i3bB-4zr0A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 10 HIS A 345
HIS A 326
HIS A 268
HIS A 244
LEU A 243
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
None
 1.18A 5m8nB-4zr0A:
undetectable		 5m8nB-4zr0A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 7 HIS A 326
HIS A 268
HIS A 244
LEU A 243
VAL A 359
 ZN  A 401 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
None
None
 1.39A 5m8rA-4zr0A:
undetectable		 5m8rA-4zr0A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 8 HIS A 326
HIS A 268
HIS A 244
LEU A 243
VAL A 359
 ZN  A 401 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
None
None
 1.40A 5m8rB-4zr0A:
undetectable		 5m8rB-4zr0A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 8 HIS A 326
HIS A 349
HIS A 272
GLY A 269
 ZN  A 401 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
None
 0.84A 5m8rC-4zr0A:
undetectable		 5m8rC-4zr0A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 244
HIS A 268
HIS A 345
HIS A 348
HIS A 349
 ZN  A 402 (-3.7A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
 1.36A 5mejA-4zr0A:
undetectable		 5mejA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 272
HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.10A 5mejA-4zr0A:
undetectable		 5mejA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 349
HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 1.14A 5mejA-4zr0A:
undetectable		 5mejA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 6 HIS A 271
HIS A 272
HIS A 268
HIS A 349
HIS A 348
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
 1.28A 5mejA-4zr0A:
undetectable		 5mejA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 6 HIS A 348
HIS A 349
HIS A 345
HIS A 272
HIS A 271
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
 1.24A 5mejA-4zr0A:
undetectable		 5mejA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 272
HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.10A 5mewA-4zr0A:
undetectable		 5mewA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 349
HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 1.14A 5mewA-4zr0A:
undetectable		 5mewA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 6 HIS A 271
HIS A 272
HIS A 268
HIS A 349
HIS A 348
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
 1.29A 5mewA-4zr0A:
undetectable		 5mewA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 6 HIS A 348
HIS A 349
HIS A 345
HIS A 272
HIS A 271
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
 1.24A 5mewA-4zr0A:
undetectable		 5mewA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 272
HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.10A 5mhuA-4zr0A:
undetectable		 5mhuA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 349
HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 1.14A 5mhuA-4zr0A:
undetectable		 5mhuA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 6 HIS A 271
HIS A 272
HIS A 268
HIS A 349
HIS A 348
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
 1.30A 5mhuA-4zr0A:
undetectable		 5mhuA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 6 HIS A 348
HIS A 349
HIS A 345
HIS A 272
HIS A 271
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
 1.25A 5mhuA-4zr0A:
undetectable		 5mhuA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 272
HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.11A 5mhvA-4zr0A:
undetectable		 5mhvA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 5 HIS A 349
HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 1.15A 5mhvA-4zr0A:
undetectable		 5mhvA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 6 HIS A 271
HIS A 272
HIS A 268
HIS A 349
HIS A 348
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
 1.30A 5mhvA-4zr0A:
undetectable		 5mhvA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 6 HIS A 348
HIS A 349
HIS A 345
HIS A 272
HIS A 271
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
 1.26A 5mhvA-4zr0A:
undetectable		 5mhvA-4zr0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 0.98A 5mhwA-4zr0A:
undetectable		 5mhwA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.98A 5mhwA-4zr0A:
undetectable		 5mhwA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 244
HIS A 349
HIS A 345
HIS A 348
 ZN  A 402 (-3.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
 1.02A 5mhxA-4zr0A:
undetectable		 5mhxA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 0.99A 5mhxA-4zr0A:
undetectable		 5mhxA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.99A 5mhxA-4zr0A:
undetectable		 5mhxA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 244
HIS A 349
HIS A 345
HIS A 348
 ZN  A 402 (-3.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
 1.02A 5mhyA-4zr0A:
undetectable		 5mhyA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 0.99A 5mhyA-4zr0A:
undetectable		 5mhyA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.99A 5mhyA-4zr0A:
undetectable		 5mhyA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.00A 5mhzA-4zr0A:
undetectable		 5mhzA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.99A 5mhzA-4zr0A:
undetectable		 5mhzA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 0.99A 5mi1A-4zr0A:
undetectable		 5mi1A-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.98A 5mi1A-4zr0A:
undetectable		 5mi1A-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 244
HIS A 349
HIS A 345
HIS A 348
 ZN  A 402 (-3.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
 1.02A 5mi2A-4zr0A:
undetectable		 5mi2A-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 0.99A 5mi2A-4zr0A:
undetectable		 5mi2A-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.99A 5mi2A-4zr0A:
undetectable		 5mi2A-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.00A 5miaA-4zr0A:
undetectable		 5miaA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 1.00A 5miaA-4zr0A:
undetectable		 5miaA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 244
HIS A 349
HIS A 345
HIS A 348
 ZN  A 402 (-3.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
 1.02A 5mibA-4zr0A:
undetectable		 5mibA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.00A 5mibA-4zr0A:
undetectable		 5mibA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.99A 5mibA-4zr0A:
undetectable		 5mibA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 244
HIS A 349
HIS A 345
HIS A 348
 ZN  A 402 (-3.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
 1.02A 5micA-4zr0A:
undetectable		 5micA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.00A 5micA-4zr0A:
undetectable		 5micA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.99A 5micA-4zr0A:
undetectable		 5micA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 244
HIS A 349
HIS A 345
HIS A 348
 ZN  A 402 (-3.7A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 402 (-3.3A)
 1.02A 5midA-4zr0A:
undetectable		 5midA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.00A 5midA-4zr0A:
undetectable		 5midA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 1.00A 5midA-4zr0A:
undetectable		 5midA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 271
HIS A 348
HIS A 349
HIS A 345
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
 1.00A 5mieA-4zr0A:
undetectable		 5mieA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 271
HIS A 272
HIS A 268
 ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.99A 5mieA-4zr0A:
undetectable		 5mieA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 348
HIS A 272
HIS A 249
 ZN  A 402 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.2A)
 0.54A 5migA-4zr0A:
undetectable		 5migA-4zr0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 10 HIS A 349
HIS A 272
HIS A 271
HIS A 348
HIS A 244
 ZN  A 401 (-3.2A)
ZN  A 402 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.7A)
 1.10A 5nzwA-4zr0A:
undetectable		 5nzwA-4zr0A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 173
HIS A 272
HIS A 268
 None
ZN  A 402 (-3.4A)
ZN  A 402 (-3.5A)
 0.68A 5oexA-4zr0A:
undetectable		 5oexA-4zr0A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 326
HIS A 330
HIS A 345
 ZN  A 401 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
 0.59A 5zrdA-4zr0A:
undetectable		 5zrdA-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 249
HIS A 268
HIS A 244
HIS A 348
 ZN  A 402 (-3.2A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
ZN  A 402 (-3.3A)
 1.06A 5zrdB-4zr0A:
undetectable		 5zrdB-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 345
HIS A 326
HIS A 330
HIS A 349
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
 0.99A 5zrdB-4zr0A:
undetectable		 5zrdB-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 349
HIS A 345
HIS A 330
HIS A 271
 ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
 1.07A 5zrdB-4zr0A:
undetectable		 5zrdB-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 244
HIS A 348
HIS A 249
HIS A 268
 ZN  A 402 (-3.7A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.5A)
 1.10A 5zrdC-4zr0A:
2.4		 5zrdC-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 249
HIS A 268
HIS A 244
HIS A 348
 ZN  A 402 (-3.2A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
ZN  A 402 (-3.3A)
 1.06A 5zrdC-4zr0A:
2.4		 5zrdC-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 268
HIS A 244
HIS A 249
HIS A 272
 ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.4A)
 1.14A 5zrdC-4zr0A:
2.4		 5zrdC-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 330
HIS A 326
HIS A 271
HIS A 349
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.2A)
 1.13A 5zrdC-4zr0A:
2.4		 5zrdC-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 330
HIS A 345
HIS A 326
HIS A 271
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.2A)
 1.11A 5zrdC-4zr0A:
2.4		 5zrdC-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 330
HIS A 349
HIS A 345
HIS A 326
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
 1.18A 5zrdC-4zr0A:
2.4		 5zrdC-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 345
HIS A 326
HIS A 330
HIS A 349
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
 0.97A 5zrdC-4zr0A:
2.4		 5zrdC-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 272
HIS A 249
HIS A 244
 ZN  A 402 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.7A)
 1.18A 5zrdC-4zr0A:
2.4		 5zrdC-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 349
HIS A 345
HIS A 330
HIS A 271
 ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
 1.05A 5zrdC-4zr0A:
2.4		 5zrdC-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 244
HIS A 348
HIS A 249
HIS A 268
 ZN  A 402 (-3.7A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.5A)
 1.09A 5zrdD-4zr0A:
undetectable		 5zrdD-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 249
HIS A 244
HIS A 348
HIS A 272
 ZN  A 402 (-3.2A)
ZN  A 402 (-3.7A)
ZN  A 402 (-3.3A)
ZN  A 402 (-3.4A)
 1.17A 5zrdD-4zr0A:
undetectable		 5zrdD-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 249
HIS A 268
HIS A 244
HIS A 348
 ZN  A 402 (-3.2A)
ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
ZN  A 402 (-3.3A)
 1.06A 5zrdD-4zr0A:
undetectable		 5zrdD-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 268
HIS A 244
HIS A 249
HIS A 272
 ZN  A 402 (-3.5A)
ZN  A 402 (-3.7A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.4A)
 1.15A 5zrdD-4zr0A:
undetectable		 5zrdD-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 330
HIS A 326
HIS A 271
HIS A 349
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.2A)
 1.10A 5zrdD-4zr0A:
undetectable		 5zrdD-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 330
HIS A 345
HIS A 326
HIS A 271
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.2A)
 1.11A 5zrdD-4zr0A:
undetectable		 5zrdD-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 345
HIS A 326
HIS A 330
HIS A 349
 ZN  A 401 (-3.5A)
ZN  A 401 (-3.4A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
 0.97A 5zrdD-4zr0A:
undetectable		 5zrdD-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 348
HIS A 272
HIS A 249
HIS A 244
 ZN  A 402 (-3.3A)
ZN  A 402 (-3.4A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.7A)
 1.17A 5zrdD-4zr0A:
undetectable		 5zrdD-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 349
HIS A 345
HIS A 330
HIS A 271
 ZN  A 401 (-3.2A)
ZN  A 401 (-3.5A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
 1.03A 5zrdD-4zr0A:
undetectable		 5zrdD-4zr0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 150
ASP A 149
GLN A 157
VAL A 282
 None
 1.12A 6bzoF-4zr0A:
2.6		 6bzoF-4zr0A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 243
TYR A 322
TYR A 319
PHE A 288
LEU A 291
 None
 1.32A 6eliA-4zr0A:
undetectable		 6eliA-4zr0A:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zr0 CERAMIDE VERY LONG
CHAIN FATTY ACID
HYDROXYLASE SCS7
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 272
HIS A 249
HIS A 268
 ZN  A 402 (-3.4A)
ZN  A 402 (-3.2A)
ZN  A 402 (-3.5A)
 0.70A 6giqa-4zr0A:
2.4		 6giqa-4zr0A:
23.31