SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zs7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN
LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama;
Lama
glama)
4 / 7 GLY H 148
ALA H 145
HIS H 173
THR L 120
None
0.90A 1gtfL-4zs7H:
undetectable
1gtfM-4zs7H:
undetectable
1gtfL-4zs7H:
15.07
1gtfM-4zs7H:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN
LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama;
Lama
glama)
4 / 8 GLY H 148
ALA H 145
HIS H 173
THR L 120
None
0.89A 1gtfN-4zs7H:
undetectable
1gtfO-4zs7H:
undetectable
1gtfN-4zs7H:
15.07
1gtfO-4zs7H:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.17A 1zzrA-4zs7L:
undetectable
1zzrB-4zs7L:
undetectable
1zzrA-4zs7L:
19.44
1zzrB-4zs7L:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.14A 1zzrA-4zs7L:
undetectable
1zzrB-4zs7L:
undetectable
1zzrA-4zs7L:
19.44
1zzrB-4zs7L:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.18A 1zzuA-4zs7L:
undetectable
1zzuB-4zs7L:
undetectable
1zzuA-4zs7L:
19.44
1zzuB-4zs7L:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.16A 1zzuA-4zs7L:
undetectable
1zzuB-4zs7L:
undetectable
1zzuA-4zs7L:
19.44
1zzuB-4zs7L:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN

(Lama
glama)
4 / 8 SER H  28
ASN H  78
GLN H  79
TRP H  73
None
1.11A 2cmlC-4zs7H:
undetectable
2cmlC-4zs7H:
20.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN
LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama;
Lama
glama)
4 / 7 TYR L  38
PRO L  46
TYR L  89
TYR H  96
None
0.74A 2oldA-4zs7L:
7.6
2oldB-4zs7L:
24.5
2oldA-4zs7L:
82.03
2oldB-4zs7L:
82.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN
LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama;
Lama
glama)
5 / 12 ILE L  50
ALA L  73
TYR L  88
GLN H  41
LEU H  47
None
1.13A 2rctA-4zs7L:
undetectable
2rctA-4zs7L:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W03_B_ADNB1588_1
(ACSD)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN

(Lama
glama)
5 / 10 LEU H  82
SER H  72
THR H  59
LEU H  84
GLN H  83
None
1.40A 2w03B-4zs7H:
0.0
2w03B-4zs7H:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.18A 3dqrA-4zs7L:
undetectable
3dqrB-4zs7L:
undetectable
3dqrA-4zs7L:
19.35
3dqrB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN

(Lama
glama)
4 / 6 LEU H 198
GLY H 199
ALA H 134
PRO H 135
None
0.53A 3huoA-4zs7H:
undetectable
3huoA-4zs7H:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.14A 3jx2A-4zs7L:
undetectable
3jx2B-4zs7L:
undetectable
3jx2A-4zs7L:
19.35
3jx2B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.13A 3jx2A-4zs7L:
undetectable
3jx2B-4zs7L:
undetectable
3jx2A-4zs7L:
19.35
3jx2B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.16A 3jx3A-4zs7L:
undetectable
3jx3B-4zs7L:
undetectable
3jx3A-4zs7L:
19.35
3jx3B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.09A 3jx3A-4zs7L:
undetectable
3jx3B-4zs7L:
undetectable
3jx3A-4zs7L:
19.35
3jx3B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.12A 3jx4A-4zs7L:
undetectable
3jx4B-4zs7L:
undetectable
3jx4A-4zs7L:
19.35
3jx4B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.13A 3jx5A-4zs7L:
undetectable
3jx5B-4zs7L:
undetectable
3jx5A-4zs7L:
19.35
3jx5B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.11A 3jx5A-4zs7L:
undetectable
3jx5B-4zs7L:
undetectable
3jx5A-4zs7L:
19.35
3jx5B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.10A 3jx6A-4zs7L:
undetectable
3jx6B-4zs7L:
undetectable
3jx6A-4zs7L:
19.35
3jx6B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.09A 3jx6A-4zs7L:
undetectable
3jx6B-4zs7L:
undetectable
3jx6A-4zs7L:
19.35
3jx6B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBR_A_ASDA129_1
(STEROID
DELTA-ISOMERASE)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN
LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
5 / 12 PHE H 175
SER L 179
VAL L 150
VAL L 148
PHE L 143
None
1.30A 3nbrA-4zs7H:
undetectable
3nbrA-4zs7H:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.10A 3nljA-4zs7L:
undetectable
3nljB-4zs7L:
undetectable
3nljA-4zs7L:
19.35
3nljB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.08A 3nljA-4zs7L:
undetectable
3nljB-4zs7L:
undetectable
3nljA-4zs7L:
19.35
3nljB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.10A 3nlpA-4zs7L:
undetectable
3nlpB-4zs7L:
undetectable
3nlpA-4zs7L:
19.35
3nlpB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.10A 3nlpA-4zs7L:
undetectable
3nlpB-4zs7L:
undetectable
3nlpA-4zs7L:
19.35
3nlpB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 8 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.11A 3nlqA-4zs7L:
undetectable
3nlqB-4zs7L:
undetectable
3nlqA-4zs7L:
19.35
3nlqB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.12A 3nlqA-4zs7L:
undetectable
3nlqB-4zs7L:
undetectable
3nlqA-4zs7L:
19.35
3nlqB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.10A 3nlrA-4zs7L:
undetectable
3nlrB-4zs7L:
undetectable
3nlrA-4zs7L:
19.35
3nlrB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 8 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.12A 3nlrA-4zs7L:
undetectable
3nlrB-4zs7L:
undetectable
3nlrA-4zs7L:
19.35
3nlrB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.18A 4cx3A-4zs7L:
undetectable
4cx3B-4zs7L:
undetectable
4cx3A-4zs7L:
19.35
4cx3B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.13A 4cx3A-4zs7L:
undetectable
4cx3B-4zs7L:
undetectable
4cx3A-4zs7L:
19.35
4cx3B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.18A 4cx4A-4zs7L:
undetectable
4cx4B-4zs7L:
undetectable
4cx4A-4zs7L:
19.35
4cx4B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.12A 4cx4A-4zs7L:
undetectable
4cx4B-4zs7L:
undetectable
4cx4A-4zs7L:
19.35
4cx4B-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 8 SER L  67
ALA L  23
SER L  74
THR L  72
None
0.92A 4iklA-4zs7L:
undetectable
4iklB-4zs7L:
undetectable
4iklA-4zs7L:
23.50
4iklB-4zs7L:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN
LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama;
Lama
glama)
5 / 12 ILE L  50
GLN L   6
TYR L  88
GLN H  41
LEU H  47
None
1.20A 4qztA-4zs7L:
undetectable
4qztA-4zs7L:
19.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 TYR L  34
SER L  36
TYR L  38
TYR L  51
None
0.74A 5aclA-4zs7L:
21.5
5aclA-4zs7L:
67.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.09A 5addA-4zs7L:
undetectable
5addB-4zs7L:
undetectable
5addA-4zs7L:
19.35
5addB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.06A 5adeA-4zs7L:
undetectable
5adeB-4zs7L:
undetectable
5adeA-4zs7L:
19.35
5adeB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN
LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama;
Lama
glama)
4 / 8 THR L 120
GLY H 148
ALA H 145
HIS H 173
None
0.87A 5eezL-4zs7L:
undetectable
5eezV-4zs7L:
undetectable
5eezL-4zs7L:
15.38
5eezV-4zs7L:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN
LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama;
Lama
glama)
4 / 8 THR L 120
GLY H 148
ALA H 145
HIS H 173
None
0.87A 5ef1L-4zs7L:
undetectable
5ef1V-4zs7L:
undetectable
5ef1L-4zs7L:
15.38
5ef1V-4zs7L:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4zs7 LLAMA FAB FRAGMENT
68F2 HEAVY CHAIN
LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama;
Lama
glama)
4 / 8 THR L 120
GLY H 148
ALA H 145
HIS H 173
None
0.87A 5ef2L-4zs7L:
undetectable
5ef2V-4zs7L:
undetectable
5ef2L-4zs7L:
15.38
5ef2V-4zs7L:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 VAL L 109
ARG L  63
VAL L  18
GLU L  85
None
1.15A 5g0pA-4zs7L:
undetectable
5g0pB-4zs7L:
undetectable
5g0pA-4zs7L:
19.35
5g0pB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 7 GLU L  85
VAL L 109
ARG L  63
VAL L  18
None
1.15A 5g0pA-4zs7L:
undetectable
5g0pB-4zs7L:
undetectable
5g0pA-4zs7L:
19.35
5g0pB-4zs7L:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)
4zs7 LLAMA FAB FRAGMENT
68F2 LIGHT CHAIN

(Lama
glama)
4 / 6 LEU L 136
ALA L 134
LEU L 182
THR L 185
None
1.05A 5l4iA-4zs7L:
undetectable
5l4iA-4zs7L:
23.50