SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.14A 1usqA-4zsoB:
undetectable		 1usqA-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.84A 1usqB-4zsoB:
undetectable		 1usqB-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.84A 1usqC-4zsoB:
undetectable		 1usqC-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.85A 1usqD-4zsoB:
undetectable		 1usqD-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.84A 1usqE-4zsoB:
undetectable		 1usqE-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.16A 2jklA-4zsoB:
undetectable		 2jklA-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.16A 2jklC-4zsoB:
undetectable		 2jklC-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.15A 2jklD-4zsoB:
undetectable		 2jklD-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		5 / 7 GLY B  54
PRO B  53
THR B  58
ILE B  51
GLY B  56
 None
 1.16A 2jklF-4zsoB:
2.1		 2jklF-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR B 118
GLU B 156
HIS B 207
 None
 0.77A 3g1uB-4zsoB:
undetectable		 3g1uB-4zsoB:
18.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		4 / 5 VAL B   2
TYR B  27
ARG B  98
TYR B 110
 None
 0.21A 4m7kH-4zsoB:
23.5		 4m7kH-4zsoB:
68.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR B  28
SER B  31
TYR B  32
 None
 0.82A 5jsdA-4zsoB:
2.1		 5jsdA-4zsoB:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR B  28
SER B  31
TYR B  32
 None
 0.82A 5jsdB-4zsoB:
undetectable		 5jsdB-4zsoB:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR B  28
SER B  31
TYR B  32
 None
 0.82A 5jsdC-4zsoB:
undetectable		 5jsdC-4zsoB:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR B  28
SER B  31
TYR B  32
 None
 0.83A 5jseA-4zsoB:
undetectable		 5jseA-4zsoB:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR B  28
SER B  31
TYR B  32
 None
 0.83A 5jseB-4zsoB:
undetectable		 5jseB-4zsoB:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 4zso ANTIBODY HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR B  28
SER B  31
TYR B  32
 None
 0.83A 5jseC-4zsoB:
undetectable		 5jseC-4zsoB:
15.49