SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 ALA A   7
LEU A   5
LEU A  57
ILE A 171
HIS A 110
 None
 1.45A 1a52A-4zu9A:
undetectable		 1a52A-4zu9A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 ALA A   7
LEU A   5
LEU A  57
ILE A 171
HIS A 110
 None
 1.45A 1a52B-4zu9A:
undetectable		 1a52B-4zu9A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 9 ALA A   7
LEU A   5
LEU A  57
ILE A 171
HIS A 110
 None
 1.43A 1ereA-4zu9A:
undetectable		 1ereA-4zu9A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 9 ALA A   7
LEU A   5
LEU A  57
ILE A 171
HIS A 110
 None
 1.44A 1ereB-4zu9A:
undetectable		 1ereB-4zu9A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 9 ALA A   7
LEU A   5
LEU A  57
ILE A 171
HIS A 110
 None
 1.43A 1ereC-4zu9A:
undetectable		 1ereC-4zu9A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 9 ALA A   7
LEU A   5
LEU A  57
ILE A 171
HIS A 110
 None
 1.43A 1ereD-4zu9A:
undetectable		 1ereD-4zu9A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 12 ARG A 198
GLY A 199
LEU A 246
VAL A 223
ALA A 236
 CYS  A2006 (-3.8A)
None
None
None
None
 1.16A 1gseA-4zu9A:
undetectable		 1gseA-4zu9A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 11 HIS A  14
GLY A  91
GLU A 140
LEU A 100
HIS A  11
 None
 1.46A 1mjqA-4zu9A:
undetectable
1mjqB-4zu9A:
undetectable		 1mjqA-4zu9A:
10.24
1mjqB-4zu9A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 8 GLU A  58
ASP A  61
ILE A  60
ASP A 185
 None
MG  A2002 ( 4.0A)
None
None
 0.91A 1p7lD-4zu9A:
undetectable		 1p7lD-4zu9A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 8 GLU A  58
ASP A  61
ILE A  60
ASP A 185
 None
MG  A2002 ( 4.0A)
None
None
 0.92A 1p7lC-4zu9A:
undetectable		 1p7lC-4zu9A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 ALA A   7
LEU A   5
LEU A  57
ILE A 171
HIS A 110
 None
 1.39A 1qkuA-4zu9A:
undetectable		 1qkuA-4zu9A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 ALA A   7
LEU A   5
LEU A  57
ILE A 171
HIS A 110
 None
 1.39A 1qkuB-4zu9A:
undetectable		 1qkuB-4zu9A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 ALA A   7
LEU A   5
LEU A  57
ILE A 171
HIS A 110
 None
 1.39A 1qkuC-4zu9A:
undetectable		 1qkuC-4zu9A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 8 GLU A  58
ASP A  61
ILE A  60
ASP A 185
 None
MG  A2002 ( 4.0A)
None
None
 0.91A 1rg9B-4zu9A:
undetectable		 1rg9B-4zu9A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 8 GLU A  58
ASP A  61
ILE A  60
ASP A 185
 None
MG  A2002 ( 4.0A)
None
None
 0.90A 1rg9A-4zu9A:
undetectable		 1rg9A-4zu9A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 8 GLU A  58
ASP A  61
ILE A  60
ASP A 185
 None
MG  A2002 ( 4.0A)
None
None
 0.90A 1rg9D-4zu9A:
undetectable		 1rg9D-4zu9A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 8 GLU A  58
ASP A  61
ILE A  60
ASP A 185
 None
MG  A2002 ( 4.0A)
None
None
 0.91A 1rg9C-4zu9A:
undetectable		 1rg9C-4zu9A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		3 / 3 TRP A 580
ARG A 578
PHE A 542
 None
 1.36A 1zeaH-4zu9A:
undetectable
1zeaL-4zu9A:
undetectable		 1zeaH-4zu9A:
14.51
1zeaL-4zu9A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 6 LEU A 451
TYR A 457
ILE A 417
GLY A 430
 None
 0.93A 2du8A-4zu9A:
undetectable		 2du8A-4zu9A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 12 LEU A 535
ILE A 559
VAL A 544
ALA A 547
ARG A 578
 None
 0.88A 2japA-4zu9A:
2.4		 2japA-4zu9A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 12 LEU A 535
ILE A 559
VAL A 544
ALA A 547
ARG A 578
 None
 0.95A 2japC-4zu9A:
6.9		 2japC-4zu9A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 7 ILE A 465
ARG A 468
TYR A 457
ASP A 422
 None
 1.09A 2qebA-4zu9A:
undetectable		 2qebA-4zu9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 7 ILE A 465
ARG A 468
TYR A 457
ASP A 422
 None
 1.03A 2qebB-4zu9A:
undetectable		 2qebB-4zu9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		3 / 3 PRO A  63
ASN A  71
ARG A 256
 GNP  A2001 ( 4.9A)
None
None
 1.06A 2qeuB-4zu9A:
undetectable		 2qeuB-4zu9A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 8 LEU A 421
LEU A 447
LYS A 448
LEU A 454
 None
 0.89A 2xn3A-4zu9A:
undetectable
2xn3B-4zu9A:
undetectable		 2xn3A-4zu9A:
22.00
2xn3B-4zu9A:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		6 / 12 ILE A  59
ASP A  61
THR A  17
THR A  24
ILE A 164
ILE A  83
 None
MG  A2002 ( 4.0A)
MG  A2002 ( 3.2A)
None
None
None
 1.48A 2yzqA-4zu9A:
undetectable		 2yzqA-4zu9A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 7 ILE A 164
LEU A  57
PHE A  50
THR A  22
 None
 0.93A 3ag2N-4zu9A:
undetectable
3ag2W-4zu9A:
undetectable		 3ag2N-4zu9A:
20.62
3ag2W-4zu9A:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 7 ILE A 164
LEU A  57
PHE A  50
THR A  22
 None
 0.89A 3ag4N-4zu9A:
undetectable
3ag4W-4zu9A:
undetectable		 3ag4N-4zu9A:
20.62
3ag4W-4zu9A:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 12 ILE A 134
LEU A 100
ILE A  92
LEU A 115
ILE A 146
 None
 1.15A 3cd2A-4zu9A:
undetectable		 3cd2A-4zu9A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 7 ILE A  48
ILE A  20
SER A 163
THR A 116
 None
 0.88A 3ua5B-4zu9A:
undetectable		 3ua5B-4zu9A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 6 GLY A 552
LEU A 561
TYR A 531
GLU A 534
 None
 1.15A 3w9tB-4zu9A:
undetectable		 3w9tB-4zu9A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 6 GLY A 552
LEU A 561
TYR A 531
GLU A 534
 None
 1.15A 3w9tE-4zu9A:
undetectable		 3w9tE-4zu9A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		3 / 3 ARG A 370
GLU A 369
PHE A 350
 None
 0.99A 4kszA-4zu9A:
undetectable		 4kszA-4zu9A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 5 VAL A 184
LEU A 197
ILE A 260
LEU A 259
 None
 0.86A 4mghA-4zu9A:
3.1		 4mghA-4zu9A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 8 GLU A  58
ASP A  61
ILE A  60
ASP A 185
 None
MG  A2002 ( 4.0A)
None
None
 0.88A 4ndnB-4zu9A:
undetectable		 4ndnB-4zu9A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 4 ASN A 175
SER A 200
ALA A 238
VAL A 237
 None
 0.92A 4x1kC-4zu9A:
2.1		 4x1kC-4zu9A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 6 LYS A 502
PRO A 501
LEU A 463
GLU A 462
 None
 1.30A 4z4cA-4zu9A:
3.4		 4z4cA-4zu9A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 6 ILE A 164
LEU A  57
PHE A  50
THR A  22
 None
 0.87A 5b1aN-4zu9A:
undetectable
5b1aW-4zu9A:
undetectable		 5b1aN-4zu9A:
20.62
5b1aW-4zu9A:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		6 / 11 VAL A 149
VAL A 114
VAL A 147
ILE A  48
ILE A 164
LEU A  19
 None
 1.28A 5e4dB-4zu9A:
undetectable		 5e4dB-4zu9A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 12 PHE A   6
GLY A  75
ILE A  76
ARG A  56
LEU A 168
 None
 1.04A 5e72A-4zu9A:
2.3		 5e72A-4zu9A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 12 PHE A   6
GLY A  75
ILE A  76
ILE A  48
LEU A 168
 None
 0.96A 5e72A-4zu9A:
2.3		 5e72A-4zu9A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 9 GLY A 335
THR A 276
ASN A 331
LEU A 333
LEU A 280
 None
 1.33A 5fhzB-4zu9A:
2.5		 5fhzB-4zu9A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 GLY A 335
THR A 276
ASN A 331
LEU A 333
LEU A 280
 None
 1.29A 5fhzC-4zu9A:
2.8		 5fhzC-4zu9A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 4 ASN A 175
SER A 200
ALA A 238
VAL A 237
 None
 0.96A 5nm5A-4zu9A:
5.4		 5nm5A-4zu9A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		3 / 3 VAL A 325
TYR A 286
GLN A 287
 None
 0.74A 5qgkA-4zu9A:
undetectable		 5qgkA-4zu9A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		3 / 3 VAL A 325
TYR A 286
GLN A 287
 None
 0.72A 5qgrA-4zu9A:
undetectable		 5qgrA-4zu9A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		3 / 3 VAL A 325
TYR A 286
GLN A 287
 None
 0.74A 5qgtA-4zu9A:
undetectable		 5qgtA-4zu9A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 ILE A  48
ILE A  59
LEU A   5
ILE A  53
ASN A  54
 None
 1.16A 5vkqA-4zu9A:
undetectable
5vkqD-4zu9A:
undetectable		 5vkqA-4zu9A:
16.20
5vkqD-4zu9A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 ILE A  53
ASN A  54
ILE A  48
ILE A  59
LEU A   5
 None
 1.14A 5vkqA-4zu9A:
undetectable
5vkqB-4zu9A:
undetectable		 5vkqA-4zu9A:
16.20
5vkqB-4zu9A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 ILE A  53
ASN A  54
ILE A  48
ILE A  59
LEU A   5
 None
 1.15A 5vkqC-4zu9A:
undetectable
5vkqD-4zu9A:
undetectable		 5vkqC-4zu9A:
16.20
5vkqD-4zu9A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		5 / 10 GLY A 297
VAL A 338
VAL A 325
ALA A 336
LEU A 272
 None
 1.12A 6czmA-4zu9A:
undetectable
6czmC-4zu9A:
undetectable		 6czmA-4zu9A:
23.71
6czmC-4zu9A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 4zu9 ELONGATION FACTOR
SELB
(Aquifex
aeolicus) 		4 / 6 PRO A 501
ILE A 495
GLY A 499
GLU A 498
 None
 1.13A 6gqiA-4zu9A:
undetectable		 6gqiA-4zu9A:
22.56