SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		4 / 7 GLY A  77
ALA A  11
HIS A  82
SER A  13
 None
 0.92A 1c9sT-4zutA:
undetectable
1c9sU-4zutA:
undetectable		 1c9sT-4zutA:
15.59
1c9sU-4zutA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		4 / 7 GLY A  77
ALA A  11
HIS A  82
SER A  13
 None
 0.91A 1gtfL-4zutA:
undetectable
1gtfM-4zutA:
undetectable		 1gtfL-4zutA:
15.59
1gtfM-4zutA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		4 / 8 GLY A  77
ALA A  11
HIS A  82
SER A  13
 None
 0.89A 1gtfN-4zutA:
undetectable
1gtfO-4zutA:
undetectable		 1gtfN-4zutA:
15.59
1gtfO-4zutA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		4 / 5 GLU A  69
ARG A  97
ASP A 116
THR A 143
 None
 1.49A 1k4tA-4zutA:
undetectable		 1k4tA-4zutA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		3 / 3 TRP A 167
GLU A  63
TYR A  59
 None
 0.97A 2a3aA-4zutA:
undetectable		 2a3aA-4zutA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		3 / 3 ASP A 116
PHE A  74
ARG A  97
 None
 0.73A 2a3aA-4zutA:
undetectable		 2a3aA-4zutA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		5 / 10 ALA A  49
THR A  31
LEU A 179
MET A   5
VAL A  28
 None
 1.38A 2wuzA-4zutA:
undetectable		 2wuzA-4zutA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		5 / 10 ALA A  49
THR A  31
LEU A 179
MET A   5
VAL A  28
 None
 1.36A 2wuzB-4zutA:
undetectable		 2wuzB-4zutA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		4 / 5 ALA A 138
GLN A 141
ILE A 142
ARG A 145
 None
 0.94A 2z0aA-4zutA:
undetectable		 2z0aA-4zutA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		4 / 8 TYR A 123
TYR A  84
TYR A 118
HIS A  93
 None
 1.00A 2zm8A-4zutA:
undetectable		 2zm8A-4zutA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		5 / 9 TYR A 123
TYR A  84
GLY A  77
TYR A 118
HIS A  93
 None
 0.98A 2zm9A-4zutA:
undetectable		 2zm9A-4zutA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		4 / 8 SER A  13
GLY A  77
ALA A  11
HIS A  82
 None
 0.89A 5eevL-4zutA:
0.6
5eevV-4zutA:
0.7		 5eevL-4zutA:
15.59
5eevV-4zutA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		4 / 8 SER A  13
GLY A  77
ALA A  11
HIS A  82
 None
 0.89A 5eewL-4zutA:
0.6
5eewV-4zutA:
0.7		 5eewL-4zutA:
15.59
5eewV-4zutA:
15.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 4zut CLASSICAL MHC CLASS
I ANTIGEN
(Equus
caballus) 		3 / 3 PRO A  47
ARG A  48
GLU A  53
 None
 0.42A 5j6hA-4zutA:
33.2		 5j6hA-4zutA:
75.91