SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zv7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		3 / 3 GLU A  81
THR A  80
LEU A 163
 None
 0.66A 1v8bC-4zv7A:
undetectable		 1v8bC-4zv7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 5 SER A 227
TYR A 135
SER A 195
ASP A 187
 None
 1.42A 1vidA-4zv7A:
undetectable		 1vidA-4zv7A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 4 GLY A  39
SER A 105
ILE A 189
HIS A 224
 None
 1.15A 1yajJ-4zv7A:
5.8		 1yajJ-4zv7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		5 / 12 ALA A 130
VAL A 190
ASP A 187
TYR A 135
SER A 202
 None
 0.95A 2dcfA-4zv7A:
undetectable		 2dcfA-4zv7A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		3 / 3 SER A 202
THR A  40
GLN A 157
 None
 0.77A 2fk8A-4zv7A:
undetectable		 2fk8A-4zv7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		5 / 12 ALA A  86
PRO A  38
GLY A 108
LEU A 109
LEU A  35
 None
 1.18A 2nv4A-4zv7A:
undetectable		 2nv4A-4zv7A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 7 SER A 105
VAL A 154
ILE A 189
ASP A 134
 None
 1.22A 2x45B-4zv7A:
undetectable		 2x45B-4zv7A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 7 SER A 105
VAL A 154
ILE A 189
ASP A 134
 None
 1.19A 2x45C-4zv7A:
undetectable		 2x45C-4zv7A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		5 / 12 GLY A  39
GLY A  41
ALA A 282
VAL A  37
VAL A 110
 None
 1.01A 2zulA-4zv7A:
undetectable		 2zulA-4zv7A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		5 / 12 ALA A 130
VAL A 190
ASP A 187
TYR A 135
SER A 202
 None
 1.07A 3a65A-4zv7A:
undetectable		 3a65A-4zv7A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		5 / 12 GLY A  39
GLY A  41
ALA A 282
VAL A  37
VAL A 110
 None
 0.99A 3dmfA-4zv7A:
undetectable		 3dmfA-4zv7A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		5 / 12 GLY A  39
GLY A  41
ALA A 282
VAL A  37
VAL A 110
 None
 1.00A 3dmhA-4zv7A:
undetectable		 3dmhA-4zv7A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		5 / 12 THR A  43
GLN A 106
GLY A 107
GLY A  19
ASN A  85
 None
 1.27A 3v3oA-4zv7A:
undetectable		 3v3oA-4zv7A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 5 VAL A 110
GLY A 107
TYR A 135
ASP A 134
 None
 1.46A 3w9tA-4zv7A:
undetectable		 3w9tA-4zv7A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 5 VAL A 110
GLY A 107
TYR A 135
ASP A 134
 None
 1.46A 3w9tF-4zv7A:
undetectable		 3w9tF-4zv7A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BCS_A_ACTA1126_0
(CHIMERIC AVIDIN)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 4 THR A 180
GLN A 247
ARG A 127
THR A 245
 None
 1.50A 4bcsA-4zv7A:
undetectable		 4bcsA-4zv7A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		5 / 12 LEU A  73
VAL A 154
ASP A 134
THR A  40
THR A 164
 None
 1.45A 4mubA-4zv7A:
undetectable		 4mubA-4zv7A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 7 THR A  62
TYR A  61
PRO A  33
SER A  56
 None
 1.03A 5b6iA-4zv7A:
2.3		 5b6iA-4zv7A:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 5 SER A 227
TYR A 135
SER A 195
ASP A 187
 None
 1.43A 5fhrA-4zv7A:
undetectable		 5fhrA-4zv7A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 6 GLY A 307
SER A 161
THR A 310
VAL A 315
 None
 1.23A 5ysiA-4zv7A:
undetectable		 5ysiA-4zv7A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 6 PHE A 118
GLY A 114
THR A  80
GLN A  77
 None
 1.16A 6ag0A-4zv7A:
undetectable		 6ag0A-4zv7A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		4 / 6 PHE A 118
GLY A 114
THR A  80
GLN A  77
 None
 1.13A 6ag0C-4zv7A:
undetectable		 6ag0C-4zv7A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 4zv7 LIPASE B
(Moesziomyces
antarcticus) 		5 / 12 GLY A 107
VAL A 190
GLY A  44
SER A  47
ALA A 281
 None
 1.22A 6c2mB-4zv7A:
undetectable		 6c2mB-4zv7A:
11.67