SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zva'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 1k2rA-4zvaA:
undetectable
1k2rB-4zvaA:
undetectable		 1k2rA-4zvaA:
18.95
1k2rB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 1k2rA-4zvaA:
undetectable
1k2rB-4zvaA:
undetectable		 1k2rA-4zvaA:
18.95
1k2rB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 1k2sA-4zvaA:
undetectable
1k2sB-4zvaA:
undetectable		 1k2sA-4zvaA:
18.95
1k2sB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 1k2tA-4zvaA:
2.0
1k2tB-4zvaA:
undetectable		 1k2tA-4zvaA:
18.95
1k2tB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 1k2tA-4zvaA:
2.0
1k2tB-4zvaA:
undetectable		 1k2tA-4zvaA:
18.95
1k2tB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 1k2uA-4zvaA:
undetectable
1k2uB-4zvaA:
undetectable		 1k2uA-4zvaA:
18.95
1k2uB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 1lzxA-4zvaA:
2.0
1lzxB-4zvaA:
undetectable		 1lzxA-4zvaA:
18.95
1lzxB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 1lzxA-4zvaA:
2.0
1lzxB-4zvaA:
undetectable		 1lzxA-4zvaA:
18.95
1lzxB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 1lzzA-4zvaA:
undetectable
1lzzB-4zvaA:
undetectable		 1lzzA-4zvaA:
18.95
1lzzB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 1lzzA-4zvaA:
undetectable
1lzzB-4zvaA:
undetectable		 1lzzA-4zvaA:
18.95
1lzzB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 1m00A-4zvaA:
undetectable
1m00B-4zvaA:
undetectable		 1m00A-4zvaA:
18.95
1m00B-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.27A 1m00A-4zvaA:
undetectable
1m00B-4zvaA:
undetectable		 1m00A-4zvaA:
18.95
1m00B-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 1mmvA-4zvaA:
1.8
1mmvB-4zvaA:
undetectable		 1mmvA-4zvaA:
18.95
1mmvB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 1mmwA-4zvaA:
undetectable
1mmwB-4zvaA:
2.1		 1mmwA-4zvaA:
18.95
1mmwB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 1mmwA-4zvaA:
undetectable
1mmwB-4zvaA:
2.1		 1mmwA-4zvaA:
18.95
1mmwB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 1om4A-4zvaA:
undetectable
1om4B-4zvaA:
undetectable		 1om4A-4zvaA:
18.86
1om4B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 1om4A-4zvaA:
undetectable
1om4B-4zvaA:
undetectable		 1om4A-4zvaA:
18.86
1om4B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 1om5A-4zvaA:
undetectable
1om5B-4zvaA:
undetectable		 1om5A-4zvaA:
18.86
1om5B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 1p6iA-4zvaA:
undetectable
1p6iB-4zvaA:
undetectable		 1p6iA-4zvaA:
18.86
1p6iB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 1p6iA-4zvaA:
undetectable
1p6iB-4zvaA:
undetectable		 1p6iA-4zvaA:
18.86
1p6iB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 1p6jA-4zvaA:
undetectable
1p6jB-4zvaA:
undetectable		 1p6jA-4zvaA:
18.86
1p6jB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 1p6jA-4zvaA:
undetectable
1p6jB-4zvaA:
undetectable		 1p6jA-4zvaA:
18.86
1p6jB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 1rs7A-4zvaA:
undetectable
1rs7B-4zvaA:
undetectable		 1rs7A-4zvaA:
18.86
1rs7B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.33A 1rs7A-4zvaA:
undetectable
1rs7B-4zvaA:
undetectable		 1rs7A-4zvaA:
18.86
1rs7B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 1zvlA-4zvaA:
undetectable
1zvlB-4zvaA:
1.5		 1zvlA-4zvaA:
19.11
1zvlB-4zvaA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 1zzqA-4zvaA:
undetectable
1zzqB-4zvaA:
undetectable		 1zzqA-4zvaA:
18.95
1zzqB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 1zzqA-4zvaA:
undetectable
1zzqB-4zvaA:
undetectable		 1zzqA-4zvaA:
18.95
1zzqB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 2g6hA-4zvaA:
undetectable
2g6hB-4zvaA:
undetectable		 2g6hA-4zvaA:
18.95
2g6hB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 2g6kA-4zvaA:
undetectable
2g6kB-4zvaA:
undetectable		 2g6kA-4zvaA:
18.95
2g6kB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 2g6kA-4zvaA:
undetectable
2g6kB-4zvaA:
undetectable		 2g6kA-4zvaA:
18.95
2g6kB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 2g6mA-4zvaA:
undetectable
2g6mB-4zvaA:
1.9		 2g6mA-4zvaA:
18.95
2g6mB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 2g6mA-4zvaA:
undetectable
2g6mB-4zvaA:
1.9		 2g6mA-4zvaA:
18.95
2g6mB-4zvaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 2hx4A-4zvaA:
undetectable
2hx4B-4zvaA:
undetectable		 2hx4A-4zvaA:
18.86
2hx4B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 LEU A  15
ALA A  79
LEU A  77
ALA A  27
 None
 0.96A 2vcvG-4zvaA:
undetectable		 2vcvG-4zvaA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 3b3mA-4zvaA:
undetectable
3b3mB-4zvaA:
undetectable		 3b3mA-4zvaA:
18.86
3b3mB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 3b3mA-4zvaA:
undetectable
3b3mB-4zvaA:
undetectable		 3b3mA-4zvaA:
18.86
3b3mB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 3b3nA-4zvaA:
undetectable
3b3nB-4zvaA:
undetectable		 3b3nA-4zvaA:
18.86
3b3nB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 3b3nA-4zvaA:
undetectable
3b3nB-4zvaA:
undetectable		 3b3nA-4zvaA:
18.86
3b3nB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 3b3oA-4zvaA:
undetectable
3b3oB-4zvaA:
undetectable		 3b3oA-4zvaA:
18.86
3b3oB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 3b3oA-4zvaA:
undetectable
3b3oB-4zvaA:
undetectable		 3b3oA-4zvaA:
18.86
3b3oB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 3b3pA-4zvaA:
undetectable
3b3pB-4zvaA:
2.1		 3b3pA-4zvaA:
18.86
3b3pB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 3b3pA-4zvaA:
undetectable
3b3pB-4zvaA:
2.1		 3b3pA-4zvaA:
18.86
3b3pB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 3fc5A-4zvaA:
undetectable
3fc5B-4zvaA:
2.1		 3fc5A-4zvaA:
18.86
3fc5B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 3fc5A-4zvaA:
undetectable
3fc5B-4zvaA:
2.1		 3fc5A-4zvaA:
18.86
3fc5B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3hsnA-4zvaA:
undetectable
3hsnB-4zvaA:
undetectable		 3hsnA-4zvaA:
18.86
3hsnB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 3hsnA-4zvaA:
undetectable
3hsnB-4zvaA:
undetectable		 3hsnA-4zvaA:
18.86
3hsnB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 3hsoA-4zvaA:
undetectable
3hsoB-4zvaA:
undetectable		 3hsoA-4zvaA:
18.86
3hsoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 3hsoA-4zvaA:
undetectable
3hsoB-4zvaA:
undetectable		 3hsoA-4zvaA:
18.86
3hsoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 3hspA-4zvaA:
undetectable
3hspB-4zvaA:
undetectable		 3hspA-4zvaA:
18.86
3hspB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 3hspA-4zvaA:
undetectable
3hspB-4zvaA:
undetectable		 3hspA-4zvaA:
18.86
3hspB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 3jt3A-4zvaA:
undetectable
3jt3B-4zvaA:
undetectable		 3jt3A-4zvaA:
18.86
3jt3B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 3jt4A-4zvaA:
undetectable
3jt4B-4zvaA:
undetectable		 3jt4A-4zvaA:
18.86
3jt4B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.40A 3jt4A-4zvaA:
undetectable
3jt4B-4zvaA:
undetectable		 3jt4A-4zvaA:
18.86
3jt4B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 3jt5A-4zvaA:
undetectable
3jt5B-4zvaA:
undetectable		 3jt5A-4zvaA:
18.86
3jt5B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 3jt5A-4zvaA:
undetectable
3jt5B-4zvaA:
undetectable		 3jt5A-4zvaA:
18.86
3jt5B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.26A 3jt6A-4zvaA:
undetectable
3jt6B-4zvaA:
undetectable		 3jt6A-4zvaA:
18.86
3jt6B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 3jt6A-4zvaA:
undetectable
3jt6B-4zvaA:
undetectable		 3jt6A-4zvaA:
18.86
3jt6B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 3jt7A-4zvaA:
undetectable
3jt7B-4zvaA:
undetectable		 3jt7A-4zvaA:
18.86
3jt7B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 3jt7A-4zvaA:
undetectable
3jt7B-4zvaA:
undetectable		 3jt7A-4zvaA:
18.86
3jt7B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 3jt8A-4zvaA:
undetectable
3jt8B-4zvaA:
undetectable		 3jt8A-4zvaA:
18.86
3jt8B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 3jt8A-4zvaA:
undetectable
3jt8B-4zvaA:
undetectable		 3jt8A-4zvaA:
18.86
3jt8B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.33A 3jt9A-4zvaA:
undetectable
3jt9B-4zvaA:
undetectable		 3jt9A-4zvaA:
18.86
3jt9B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 3jt9A-4zvaA:
undetectable
3jt9B-4zvaA:
undetectable		 3jt9A-4zvaA:
18.86
3jt9B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3jtaA-4zvaA:
undetectable
3jtaB-4zvaA:
undetectable		 3jtaA-4zvaA:
18.86
3jtaB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.33A 3jtaA-4zvaA:
undetectable
3jtaB-4zvaA:
undetectable		 3jtaA-4zvaA:
18.86
3jtaB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.26A 3jwsA-4zvaA:
undetectable
3jwsB-4zvaA:
undetectable		 3jwsA-4zvaA:
18.88
3jwsB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.27A 3jwsA-4zvaA:
undetectable
3jwsB-4zvaA:
undetectable		 3jwsA-4zvaA:
18.88
3jwsB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 3jwtA-4zvaA:
undetectable
3jwtB-4zvaA:
undetectable		 3jwtA-4zvaA:
18.88
3jwtB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.28A 3jwtA-4zvaA:
undetectable
3jwtB-4zvaA:
undetectable		 3jwtA-4zvaA:
18.88
3jwtB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.24A 3jwuA-4zvaA:
undetectable
3jwuB-4zvaA:
undetectable		 3jwuA-4zvaA:
18.88
3jwuB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.27A 3jwuA-4zvaA:
undetectable
3jwuB-4zvaA:
undetectable		 3jwuA-4zvaA:
18.88
3jwuB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 3jwvA-4zvaA:
undetectable
3jwvB-4zvaA:
undetectable		 3jwvA-4zvaA:
18.88
3jwvB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 3jwvA-4zvaA:
undetectable
3jwvB-4zvaA:
undetectable		 3jwvA-4zvaA:
18.88
3jwvB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.24A 3jx0A-4zvaA:
1.4
3jx0B-4zvaA:
undetectable		 3jx0A-4zvaA:
18.86
3jx0B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.27A 3jx0A-4zvaA:
1.4
3jx0B-4zvaA:
undetectable		 3jx0A-4zvaA:
18.86
3jx0B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 3jx1A-4zvaA:
undetectable
3jx1B-4zvaA:
undetectable		 3jx1A-4zvaA:
18.86
3jx1B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 3jx1A-4zvaA:
undetectable
3jx1B-4zvaA:
undetectable		 3jx1A-4zvaA:
18.86
3jx1B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		5 / 12 ALA A 147
LEU A  56
LEU A 115
GLY A 111
PHE A 112
 None
HEM  A 201 ( 4.9A)
None
HEM  A 201 ( 3.9A)
HEM  A 201 (-3.6A)
 1.17A 3k2hA-4zvaA:
undetectable		 3k2hA-4zvaA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		5 / 12 ALA A 147
LEU A  56
LEU A 115
GLY A 111
PHE A 112
 None
HEM  A 201 ( 4.9A)
None
HEM  A 201 ( 3.9A)
HEM  A 201 (-3.6A)
 1.13A 3k2hB-4zvaA:
undetectable		 3k2hB-4zvaA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 3n2rA-4zvaA:
undetectable
3n2rB-4zvaA:
undetectable		 3n2rA-4zvaA:
18.86
3n2rB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 3n2rA-4zvaA:
undetectable
3n2rB-4zvaA:
undetectable		 3n2rA-4zvaA:
18.86
3n2rB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.33A 3n5vA-4zvaA:
undetectable
3n5vB-4zvaA:
undetectable		 3n5vA-4zvaA:
18.86
3n5vB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.33A 3n5vA-4zvaA:
undetectable
3n5vB-4zvaA:
undetectable		 3n5vA-4zvaA:
18.86
3n5vB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 3n5yA-4zvaA:
undetectable
3n5yB-4zvaA:
undetectable		 3n5yA-4zvaA:
18.86
3n5yB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.33A 3n5yA-4zvaA:
undetectable
3n5yB-4zvaA:
undetectable		 3n5yA-4zvaA:
18.86
3n5yB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 3n5zA-4zvaA:
undetectable
3n5zB-4zvaA:
undetectable		 3n5zA-4zvaA:
18.86
3n5zB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 3n5zA-4zvaA:
undetectable
3n5zB-4zvaA:
undetectable		 3n5zA-4zvaA:
18.86
3n5zB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 6 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 3n65A-4zvaA:
undetectable
3n65B-4zvaA:
undetectable		 3n65A-4zvaA:
18.86
3n65B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 3nlkA-4zvaA:
undetectable
3nlkB-4zvaA:
undetectable		 3nlkA-4zvaA:
18.88
3nlkB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 3nlkA-4zvaA:
undetectable
3nlkB-4zvaA:
undetectable		 3nlkA-4zvaA:
18.88
3nlkB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3nlmA-4zvaA:
undetectable
3nlmB-4zvaA:
undetectable		 3nlmA-4zvaA:
18.86
3nlmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.30A 3nlmA-4zvaA:
undetectable
3nlmB-4zvaA:
undetectable		 3nlmA-4zvaA:
18.86
3nlmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 3nlnA-4zvaA:
undetectable
3nlnB-4zvaA:
undetectable		 3nlnA-4zvaA:
18.88
3nlnB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.28A 3nlnA-4zvaA:
undetectable
3nlnB-4zvaA:
undetectable		 3nlnA-4zvaA:
18.88
3nlnB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 3nloA-4zvaA:
undetectable
3nloB-4zvaA:
undetectable		 3nloA-4zvaA:
18.88
3nloB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.28A 3nloA-4zvaA:
undetectable
3nloB-4zvaA:
undetectable		 3nloA-4zvaA:
18.88
3nloB-4zvaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 3nlvA-4zvaA:
undetectable
3nlvB-4zvaA:
1.5		 3nlvA-4zvaA:
18.86
3nlvB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.28A 3nlvA-4zvaA:
undetectable
3nlvB-4zvaA:
1.5		 3nlvA-4zvaA:
18.86
3nlvB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 3nlwA-4zvaA:
undetectable
3nlwB-4zvaA:
undetectable		 3nlwA-4zvaA:
18.86
3nlwB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3nlxA-4zvaA:
undetectable
3nlxB-4zvaA:
undetectable		 3nlxA-4zvaA:
18.86
3nlxB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 3nlxA-4zvaA:
undetectable
3nlxB-4zvaA:
undetectable		 3nlxA-4zvaA:
18.86
3nlxB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 3nlyA-4zvaA:
undetectable
3nlyB-4zvaA:
undetectable		 3nlyA-4zvaA:
18.86
3nlyB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 3nlzA-4zvaA:
undetectable
3nlzB-4zvaA:
undetectable		 3nlzA-4zvaA:
18.86
3nlzB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 3nlzA-4zvaA:
undetectable
3nlzB-4zvaA:
undetectable		 3nlzA-4zvaA:
18.86
3nlzB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 3nm0A-4zvaA:
1.8
3nm0B-4zvaA:
undetectable		 3nm0A-4zvaA:
18.86
3nm0B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 3nm0A-4zvaA:
undetectable
3nm0B-4zvaA:
undetectable		 3nm0A-4zvaA:
18.86
3nm0B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3nnyA-4zvaA:
undetectable
3nnyB-4zvaA:
undetectable		 3nnyA-4zvaA:
18.86
3nnyB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 3nnyA-4zvaA:
undetectable
3nnyB-4zvaA:
undetectable		 3nnyA-4zvaA:
18.86
3nnyB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 3nnzA-4zvaA:
undetectable
3nnzB-4zvaA:
undetectable		 3nnzA-4zvaA:
18.86
3nnzB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.26A 3nnzA-4zvaA:
undetectable
3nnzB-4zvaA:
undetectable		 3nnzA-4zvaA:
18.86
3nnzB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 3pneA-4zvaA:
undetectable
3pneB-4zvaA:
undetectable		 3pneA-4zvaA:
18.86
3pneB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 3pneA-4zvaA:
undetectable
3pneB-4zvaA:
undetectable		 3pneA-4zvaA:
18.86
3pneB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3pnfA-4zvaA:
undetectable
3pnfB-4zvaA:
undetectable		 3pnfA-4zvaA:
18.86
3pnfB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.30A 3pnfA-4zvaA:
undetectable
3pnfB-4zvaA:
undetectable		 3pnfA-4zvaA:
18.86
3pnfB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 3pngA-4zvaA:
undetectable
3pngB-4zvaA:
undetectable		 3pngA-4zvaA:
18.86
3pngB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 3pngA-4zvaA:
undetectable
3pngB-4zvaA:
undetectable		 3pngA-4zvaA:
18.86
3pngB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 3q99A-4zvaA:
undetectable
3q99B-4zvaA:
undetectable		 3q99A-4zvaA:
18.86
3q99B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 3q99A-4zvaA:
undetectable
3q99B-4zvaA:
undetectable		 3q99A-4zvaA:
18.86
3q99B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 3q9aA-4zvaA:
undetectable
3q9aB-4zvaA:
undetectable		 3q9aA-4zvaA:
18.86
3q9aB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.41A 3q9aA-4zvaA:
undetectable
3q9aB-4zvaA:
undetectable		 3q9aA-4zvaA:
18.86
3q9aB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 3rqjA-4zvaA:
undetectable
3rqjB-4zvaA:
undetectable		 3rqjA-4zvaA:
18.86
3rqjB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.33A 3rqkA-4zvaA:
undetectable
3rqkB-4zvaA:
undetectable		 3rqkA-4zvaA:
18.86
3rqkB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3rqlA-4zvaA:
1.9
3rqlB-4zvaA:
undetectable		 3rqlA-4zvaA:
18.86
3rqlB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 3rqlA-4zvaA:
undetectable
3rqlB-4zvaA:
undetectable		 3rqlA-4zvaA:
18.86
3rqlB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3rqmA-4zvaA:
undetectable
3rqmB-4zvaA:
undetectable		 3rqmA-4zvaA:
18.86
3rqmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 3rqmA-4zvaA:
undetectable
3rqmB-4zvaA:
undetectable		 3rqmA-4zvaA:
18.86
3rqmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3rqnA-4zvaA:
2.0
3rqnB-4zvaA:
undetectable		 3rqnA-4zvaA:
18.86
3rqnB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 3rqnA-4zvaA:
2.0
3rqnB-4zvaA:
undetectable		 3rqnA-4zvaA:
18.86
3rqnB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.33A 3svpA-4zvaA:
undetectable
3svpB-4zvaA:
undetectable		 3svpA-4zvaA:
18.86
3svpB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.33A 3tylA-4zvaA:
undetectable
3tylB-4zvaA:
undetectable		 3tylA-4zvaA:
18.86
3tylB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 3tylA-4zvaA:
undetectable
3tylB-4zvaA:
undetectable		 3tylA-4zvaA:
18.86
3tylB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 3tymA-4zvaA:
1.5
3tymB-4zvaA:
undetectable		 3tymA-4zvaA:
18.86
3tymB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.30A 3tymA-4zvaA:
1.5
3tymB-4zvaA:
undetectable		 3tymA-4zvaA:
18.86
3tymB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 3tynA-4zvaA:
undetectable
3tynB-4zvaA:
undetectable		 3tynA-4zvaA:
18.86
3tynB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.33A 3tynA-4zvaA:
undetectable
3tynB-4zvaA:
undetectable		 3tynA-4zvaA:
18.86
3tynB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 3tyoA-4zvaA:
1.4
3tyoB-4zvaA:
undetectable		 3tyoA-4zvaA:
18.86
3tyoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 3tyoA-4zvaA:
1.4
3tyoB-4zvaA:
undetectable		 3tyoA-4zvaA:
18.86
3tyoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.33A 3ufoA-4zvaA:
1.4
3ufoB-4zvaA:
undetectable		 3ufoA-4zvaA:
18.86
3ufoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 3ufoA-4zvaA:
1.4
3ufoB-4zvaA:
undetectable		 3ufoA-4zvaA:
18.86
3ufoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.41A 3ufpA-4zvaA:
undetectable
3ufpB-4zvaA:
2.1		 3ufpA-4zvaA:
18.86
3ufpB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 3ufqA-4zvaA:
undetectable
3ufqB-4zvaA:
undetectable		 3ufqA-4zvaA:
18.86
3ufqB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 3ufsA-4zvaA:
undetectable
3ufsB-4zvaA:
undetectable		 3ufsA-4zvaA:
18.86
3ufsB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.33A 3uftA-4zvaA:
undetectable
3uftB-4zvaA:
undetectable		 3uftA-4zvaA:
18.86
3uftB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.40A 3uftA-4zvaA:
undetectable
3uftB-4zvaA:
undetectable		 3uftA-4zvaA:
18.86
3uftB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 3ufuA-4zvaA:
undetectable
3ufuB-4zvaA:
undetectable		 3ufuA-4zvaA:
18.86
3ufuB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.30A 3ufuA-4zvaA:
undetectable
3ufuB-4zvaA:
undetectable		 3ufuA-4zvaA:
18.86
3ufuB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3ufvA-4zvaA:
undetectable
3ufvB-4zvaA:
undetectable		 3ufvA-4zvaA:
18.86
3ufvB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.43A 3ufvA-4zvaA:
undetectable
3ufvB-4zvaA:
undetectable		 3ufvA-4zvaA:
18.86
3ufvB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 LEU A 115
VAL A  76
LEU A  77
ALA A  35
 None
 0.92A 3uniB-4zvaA:
undetectable		 3uniB-4zvaA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4camA-4zvaA:
1.5
4camB-4zvaA:
undetectable		 4camA-4zvaA:
18.86
4camB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 4camA-4zvaA:
1.5
4camB-4zvaA:
undetectable		 4camA-4zvaA:
18.86
4camB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 4canA-4zvaA:
undetectable
4canB-4zvaA:
undetectable		 4canA-4zvaA:
18.86
4canB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 4canA-4zvaA:
undetectable
4canB-4zvaA:
undetectable		 4canA-4zvaA:
18.86
4canB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 4caoA-4zvaA:
undetectable
4caoB-4zvaA:
undetectable		 4caoA-4zvaA:
18.86
4caoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 4caoA-4zvaA:
undetectable
4caoB-4zvaA:
undetectable		 4caoA-4zvaA:
18.86
4caoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4capA-4zvaA:
1.5
4capB-4zvaA:
undetectable		 4capA-4zvaA:
18.86
4capB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 4capA-4zvaA:
undetectable
4capB-4zvaA:
undetectable		 4capA-4zvaA:
18.86
4capB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4caqA-4zvaA:
undetectable
4caqB-4zvaA:
undetectable		 4caqA-4zvaA:
18.86
4caqB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 4caqA-4zvaA:
undetectable
4caqB-4zvaA:
undetectable		 4caqA-4zvaA:
18.86
4caqB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.26A 4cdtA-4zvaA:
undetectable
4cdtB-4zvaA:
undetectable		 4cdtA-4zvaA:
18.86
4cdtB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 4cdtA-4zvaA:
undetectable
4cdtB-4zvaA:
undetectable		 4cdtA-4zvaA:
18.86
4cdtB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 4ctpA-4zvaA:
undetectable
4ctpB-4zvaA:
undetectable		 4ctpA-4zvaA:
18.86
4ctpB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4ctrA-4zvaA:
undetectable
4ctrB-4zvaA:
undetectable		 4ctrA-4zvaA:
18.86
4ctrB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 4ctrA-4zvaA:
undetectable
4ctrB-4zvaA:
undetectable		 4ctrA-4zvaA:
18.86
4ctrB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 4cttA-4zvaA:
undetectable
4cttB-4zvaA:
undetectable		 4cttA-4zvaA:
18.86
4cttB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.33A 4cttA-4zvaA:
undetectable
4cttB-4zvaA:
undetectable		 4cttA-4zvaA:
18.86
4cttB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 4ctuA-4zvaA:
undetectable
4ctuB-4zvaA:
1.9		 4ctuA-4zvaA:
18.86
4ctuB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 4ctuA-4zvaA:
undetectable
4ctuB-4zvaA:
1.9		 4ctuA-4zvaA:
18.86
4ctuB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 4ctvA-4zvaA:
undetectable
4ctvB-4zvaA:
undetectable		 4ctvA-4zvaA:
18.86
4ctvB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 4ctvA-4zvaA:
undetectable
4ctvB-4zvaA:
undetectable		 4ctvA-4zvaA:
18.86
4ctvB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4ctwA-4zvaA:
undetectable
4ctwB-4zvaA:
undetectable		 4ctwA-4zvaA:
18.86
4ctwB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.30A 4ctwA-4zvaA:
undetectable
4ctwB-4zvaA:
undetectable		 4ctwA-4zvaA:
18.86
4ctwB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 4ctxA-4zvaA:
undetectable
4ctxB-4zvaA:
undetectable		 4ctxA-4zvaA:
18.86
4ctxB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.33A 4ctxA-4zvaA:
undetectable
4ctxB-4zvaA:
undetectable		 4ctxA-4zvaA:
18.86
4ctxB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 4cx5A-4zvaA:
undetectable
4cx5B-4zvaA:
undetectable		 4cx5A-4zvaA:
18.86
4cx5B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.28A 4cx5A-4zvaA:
undetectable
4cx5B-4zvaA:
undetectable		 4cx5A-4zvaA:
18.86
4cx5B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 4d1nA-4zvaA:
undetectable
4d1nB-4zvaA:
undetectable		 4d1nA-4zvaA:
18.56
4d1nB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 4d1nA-4zvaA:
undetectable
4d1nB-4zvaA:
undetectable		 4d1nA-4zvaA:
18.56
4d1nB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.42A 4d1nC-4zvaA:
undetectable
4d1nD-4zvaA:
undetectable		 4d1nC-4zvaA:
18.56
4d1nD-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.26A 4d2yA-4zvaA:
undetectable
4d2yB-4zvaA:
undetectable		 4d2yA-4zvaA:
18.86
4d2yB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.28A 4d2yA-4zvaA:
undetectable
4d2yB-4zvaA:
undetectable		 4d2yA-4zvaA:
18.86
4d2yB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4d2zA-4zvaA:
1.5
4d2zB-4zvaA:
undetectable		 4d2zA-4zvaA:
18.86
4d2zB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.28A 4d2zA-4zvaA:
undetectable
4d2zB-4zvaA:
undetectable		 4d2zA-4zvaA:
18.86
4d2zB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 4d30A-4zvaA:
undetectable
4d30B-4zvaA:
undetectable		 4d30A-4zvaA:
18.86
4d30B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 4d30A-4zvaA:
undetectable
4d30B-4zvaA:
undetectable		 4d30A-4zvaA:
18.86
4d30B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.38A 4d31A-4zvaA:
undetectable
4d31B-4zvaA:
undetectable		 4d31A-4zvaA:
18.86
4d31B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.40A 4d31A-4zvaA:
undetectable
4d31B-4zvaA:
undetectable		 4d31A-4zvaA:
18.86
4d31B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 4d32A-4zvaA:
undetectable
4d32B-4zvaA:
undetectable		 4d32A-4zvaA:
18.86
4d32B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.27A 4d32A-4zvaA:
undetectable
4d32B-4zvaA:
undetectable		 4d32A-4zvaA:
18.86
4d32B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4d3bA-4zvaA:
2.2
4d3bB-4zvaA:
undetectable		 4d3bA-4zvaA:
18.86
4d3bB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 4d3bA-4zvaA:
2.2
4d3bB-4zvaA:
undetectable		 4d3bA-4zvaA:
18.86
4d3bB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 4d7oA-4zvaA:
undetectable
4d7oB-4zvaA:
2.1		 4d7oA-4zvaA:
18.86
4d7oB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.27A 4d7oA-4zvaA:
undetectable
4d7oB-4zvaA:
2.1		 4d7oA-4zvaA:
18.86
4d7oB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.33A 4euxA-4zvaA:
undetectable
4euxB-4zvaA:
2.1		 4euxA-4zvaA:
18.86
4euxB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 4euxA-4zvaA:
undetectable
4euxB-4zvaA:
2.1		 4euxA-4zvaA:
18.86
4euxB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4fvwA-4zvaA:
undetectable
4fvwB-4zvaA:
undetectable		 4fvwA-4zvaA:
18.86
4fvwB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 4fvwA-4zvaA:
undetectable
4fvwB-4zvaA:
undetectable		 4fvwA-4zvaA:
18.86
4fvwB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 4fvxA-4zvaA:
undetectable
4fvxB-4zvaA:
undetectable		 4fvxA-4zvaA:
18.86
4fvxB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 4fvxA-4zvaA:
undetectable
4fvxB-4zvaA:
undetectable		 4fvxA-4zvaA:
18.86
4fvxB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.38A 4fvyA-4zvaA:
undetectable
4fvyB-4zvaA:
undetectable		 4fvyA-4zvaA:
18.86
4fvyB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 4fvyA-4zvaA:
undetectable
4fvyB-4zvaA:
undetectable		 4fvyA-4zvaA:
18.86
4fvyB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 4fvzA-4zvaA:
undetectable
4fvzB-4zvaA:
undetectable		 4fvzA-4zvaA:
18.86
4fvzB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.33A 4fvzA-4zvaA:
undetectable
4fvzB-4zvaA:
undetectable		 4fvzA-4zvaA:
18.86
4fvzB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 4fw0A-4zvaA:
undetectable
4fw0B-4zvaA:
undetectable		 4fw0A-4zvaA:
18.86
4fw0B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 4fw0A-4zvaA:
undetectable
4fw0B-4zvaA:
undetectable		 4fw0A-4zvaA:
18.86
4fw0B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 4gqeA-4zvaA:
undetectable
4gqeB-4zvaA:
undetectable		 4gqeA-4zvaA:
18.86
4gqeB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 4gqeA-4zvaA:
undetectable
4gqeB-4zvaA:
undetectable		 4gqeA-4zvaA:
18.86
4gqeB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 4imtA-4zvaA:
undetectable
4imtB-4zvaA:
undetectable		 4imtA-4zvaA:
18.86
4imtB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 6 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4imuA-4zvaA:
undetectable
4imuB-4zvaA:
undetectable		 4imuA-4zvaA:
18.86
4imuB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 6 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 4imuA-4zvaA:
undetectable
4imuB-4zvaA:
undetectable		 4imuA-4zvaA:
18.86
4imuB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 4imwA-4zvaA:
undetectable
4imwB-4zvaA:
2.0		 4imwA-4zvaA:
18.86
4imwB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 4jsfA-4zvaA:
undetectable
4jsfB-4zvaA:
undetectable		 4jsfA-4zvaA:
18.86
4jsfB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4jsgA-4zvaA:
undetectable
4jsgB-4zvaA:
undetectable		 4jsgA-4zvaA:
18.86
4jsgB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 4jsiA-4zvaA:
undetectable
4jsiB-4zvaA:
1.5		 4jsiA-4zvaA:
18.86
4jsiB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 4jsiA-4zvaA:
undetectable
4jsiB-4zvaA:
1.5		 4jsiA-4zvaA:
18.86
4jsiB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4jsjA-4zvaA:
undetectable
4jsjB-4zvaA:
undetectable		 4jsjA-4zvaA:
18.86
4jsjB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 4jsjA-4zvaA:
undetectable
4jsjB-4zvaA:
1.5		 4jsjA-4zvaA:
18.86
4jsjB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 4k5dA-4zvaA:
undetectable
4k5dB-4zvaA:
undetectable		 4k5dA-4zvaA:
18.86
4k5dB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 4k5eA-4zvaA:
undetectable
4k5eB-4zvaA:
undetectable		 4k5eA-4zvaA:
18.86
4k5eB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.26A 4k5fA-4zvaA:
undetectable
4k5fB-4zvaA:
undetectable		 4k5fA-4zvaA:
18.86
4k5fB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 4k5fA-4zvaA:
undetectable
4k5fB-4zvaA:
undetectable		 4k5fA-4zvaA:
18.86
4k5fB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 4k5gA-4zvaA:
undetectable
4k5gB-4zvaA:
undetectable		 4k5gA-4zvaA:
18.86
4k5gB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 4kchA-4zvaA:
undetectable
4kchB-4zvaA:
undetectable		 4kchA-4zvaA:
18.86
4kchB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.27A 4kchA-4zvaA:
undetectable
4kchB-4zvaA:
undetectable		 4kchA-4zvaA:
18.86
4kchB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 4kciA-4zvaA:
undetectable
4kciB-4zvaA:
undetectable		 4kciA-4zvaA:
18.86
4kciB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 4kcjA-4zvaA:
1.4
4kcjB-4zvaA:
undetectable		 4kcjA-4zvaA:
18.86
4kcjB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 4kckA-4zvaA:
undetectable
4kckB-4zvaA:
undetectable		 4kckA-4zvaA:
18.86
4kckB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 4kckA-4zvaA:
undetectable
4kckB-4zvaA:
undetectable		 4kckA-4zvaA:
18.86
4kckB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 4kclA-4zvaA:
undetectable
4kclB-4zvaA:
2.1		 4kclA-4zvaA:
18.86
4kclB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 4kcmA-4zvaA:
undetectable
4kcmB-4zvaA:
undetectable		 4kcmA-4zvaA:
18.86
4kcmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 4kcmA-4zvaA:
undetectable
4kcmB-4zvaA:
undetectable		 4kcmA-4zvaA:
18.86
4kcmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 4kcnA-4zvaA:
undetectable
4kcnB-4zvaA:
undetectable		 4kcnA-4zvaA:
18.86
4kcnB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4kcoA-4zvaA:
undetectable
4kcoB-4zvaA:
undetectable		 4kcoA-4zvaA:
18.86
4kcoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 4kcoA-4zvaA:
undetectable
4kcoB-4zvaA:
undetectable		 4kcoA-4zvaA:
18.86
4kcoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.47A 4uchA-4zvaA:
undetectable
4uchB-4zvaA:
undetectable		 4uchA-4zvaA:
18.56
4uchB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4uh0A-4zvaA:
1.3
4uh0B-4zvaA:
undetectable		 4uh0A-4zvaA:
18.86
4uh0B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4uh1A-4zvaA:
undetectable
4uh1B-4zvaA:
undetectable		 4uh1A-4zvaA:
18.86
4uh1B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 4uh4A-4zvaA:
undetectable
4uh4B-4zvaA:
undetectable		 4uh4A-4zvaA:
18.86
4uh4B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 4uh4A-4zvaA:
undetectable
4uh4B-4zvaA:
undetectable		 4uh4A-4zvaA:
18.86
4uh4B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.41A 4uh5A-4zvaA:
undetectable
4uh5B-4zvaA:
undetectable		 4uh5A-4zvaA:
18.56
4uh5B-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4upmA-4zvaA:
undetectable
4upmB-4zvaA:
undetectable		 4upmA-4zvaA:
18.86
4upmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 4upmA-4zvaA:
undetectable
4upmB-4zvaA:
undetectable		 4upmA-4zvaA:
18.86
4upmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 4upnA-4zvaA:
undetectable
4upnB-4zvaA:
2.1		 4upnA-4zvaA:
18.86
4upnB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 4upnA-4zvaA:
undetectable
4upnB-4zvaA:
2.1		 4upnA-4zvaA:
18.86
4upnB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 4upoA-4zvaA:
undetectable
4upoB-4zvaA:
undetectable		 4upoA-4zvaA:
18.86
4upoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.26A 4uppA-4zvaA:
undetectable
4uppB-4zvaA:
undetectable		 4uppA-4zvaA:
18.86
4uppB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.29A 4uppA-4zvaA:
undetectable
4uppB-4zvaA:
undetectable		 4uppA-4zvaA:
18.86
4uppB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 4v3uA-4zvaA:
undetectable
4v3uB-4zvaA:
undetectable		 4v3uA-4zvaA:
18.56
4v3uB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.32A 4v3uA-4zvaA:
undetectable
4v3uB-4zvaA:
undetectable		 4v3uA-4zvaA:
18.56
4v3uB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.33A 4v3uC-4zvaA:
undetectable
4v3uD-4zvaA:
undetectable		 4v3uC-4zvaA:
18.56
4v3uD-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 4v3uC-4zvaA:
2.0
4v3uD-4zvaA:
undetectable		 4v3uC-4zvaA:
18.56
4v3uD-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 4v3vA-4zvaA:
1.4
4v3vB-4zvaA:
undetectable		 4v3vA-4zvaA:
18.86
4v3vB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 4v3xA-4zvaA:
undetectable
4v3xB-4zvaA:
undetectable		 4v3xA-4zvaA:
18.86
4v3xB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 4v3xA-4zvaA:
undetectable
4v3xB-4zvaA:
undetectable		 4v3xA-4zvaA:
18.86
4v3xB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 4v3yA-4zvaA:
undetectable
4v3yB-4zvaA:
undetectable		 4v3yA-4zvaA:
18.86
4v3yB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.27A 4v3yA-4zvaA:
undetectable
4v3yB-4zvaA:
undetectable		 4v3yA-4zvaA:
18.86
4v3yB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.31A 4v3zA-4zvaA:
undetectable
4v3zB-4zvaA:
undetectable		 4v3zA-4zvaA:
18.86
4v3zB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 5adcA-4zvaA:
undetectable
5adcB-4zvaA:
undetectable		 5adcA-4zvaA:
18.86
5adcB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 5adfA-4zvaA:
undetectable
5adfB-4zvaA:
2.1		 5adfA-4zvaA:
18.56
5adfB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 5agkA-4zvaA:
undetectable
5agkB-4zvaA:
2.1		 5agkA-4zvaA:
18.86
5agkB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 5agkA-4zvaA:
undetectable
5agkB-4zvaA:
2.1		 5agkA-4zvaA:
18.86
5agkB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 5aglA-4zvaA:
undetectable
5aglB-4zvaA:
undetectable		 5aglA-4zvaA:
18.86
5aglB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 5aglA-4zvaA:
undetectable
5aglB-4zvaA:
undetectable		 5aglA-4zvaA:
18.86
5aglB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 5agmA-4zvaA:
undetectable
5agmB-4zvaA:
undetectable		 5agmA-4zvaA:
18.86
5agmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 5agmA-4zvaA:
undetectable
5agmB-4zvaA:
undetectable		 5agmA-4zvaA:
18.86
5agmB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 5agnA-4zvaA:
undetectable
5agnB-4zvaA:
undetectable		 5agnA-4zvaA:
18.86
5agnB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 5agoA-4zvaA:
undetectable
5agoB-4zvaA:
undetectable		 5agoA-4zvaA:
18.86
5agoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 5agoA-4zvaA:
undetectable
5agoB-4zvaA:
undetectable		 5agoA-4zvaA:
18.86
5agoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 5agpA-4zvaA:
undetectable
5agpB-4zvaA:
undetectable		 5agpA-4zvaA:
18.86
5agpB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.43A 5fvsA-4zvaA:
undetectable
5fvsB-4zvaA:
undetectable		 5fvsA-4zvaA:
18.86
5fvsB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.39A 5fvtA-4zvaA:
undetectable
5fvtB-4zvaA:
undetectable		 5fvtA-4zvaA:
18.86
5fvtB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 5fw0A-4zvaA:
1.5
5fw0B-4zvaA:
undetectable		 5fw0A-4zvaA:
18.86
5fw0B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 5g0oA-4zvaA:
1.8
5g0oB-4zvaA:
undetectable		 5g0oA-4zvaA:
18.86
5g0oB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 5g0oA-4zvaA:
1.8
5g0oB-4zvaA:
undetectable		 5g0oA-4zvaA:
18.86
5g0oB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 5unrA-4zvaA:
1.5
5unrB-4zvaA:
undetectable		 5unrA-4zvaA:
18.86
5unrB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 5uo0A-4zvaA:
1.8
5uo0B-4zvaA:
undetectable		 5uo0A-4zvaA:
18.86
5uo0B-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 5vujA-4zvaA:
undetectable
5vujB-4zvaA:
undetectable		 5vujA-4zvaA:
18.86
5vujB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.30A 5vujA-4zvaA:
undetectable
5vujB-4zvaA:
undetectable		 5vujA-4zvaA:
18.86
5vujB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 5vukA-4zvaA:
undetectable
5vukB-4zvaA:
undetectable		 5vukA-4zvaA:
18.86
5vukB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 5vukA-4zvaA:
undetectable
5vukB-4zvaA:
undetectable		 5vukA-4zvaA:
18.86
5vukB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 5vulA-4zvaA:
1.5
5vulB-4zvaA:
undetectable		 5vulA-4zvaA:
18.86
5vulB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.25A 5vulA-4zvaA:
1.5
5vulB-4zvaA:
undetectable		 5vulA-4zvaA:
18.86
5vulB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 5vumA-4zvaA:
1.4
5vumB-4zvaA:
undetectable		 5vumA-4zvaA:
18.86
5vumB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 5vumA-4zvaA:
1.4
5vumB-4zvaA:
undetectable		 5vumA-4zvaA:
18.86
5vumB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 5vunA-4zvaA:
undetectable
5vunB-4zvaA:
undetectable		 5vunA-4zvaA:
18.86
5vunB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 5vunA-4zvaA:
undetectable
5vunB-4zvaA:
undetectable		 5vunA-4zvaA:
18.86
5vunB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 5vuoA-4zvaA:
2.2
5vuoB-4zvaA:
undetectable		 5vuoA-4zvaA:
18.86
5vuoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 5vuoA-4zvaA:
2.2
5vuoB-4zvaA:
undetectable		 5vuoA-4zvaA:
18.86
5vuoB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 5vupA-4zvaA:
undetectable
5vupB-4zvaA:
undetectable		 5vupA-4zvaA:
18.86
5vupB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.26A 5vupA-4zvaA:
undetectable
5vupB-4zvaA:
undetectable		 5vupA-4zvaA:
18.86
5vupB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.39A 5vuqA-4zvaA:
undetectable
5vuqB-4zvaA:
undetectable		 5vuqA-4zvaA:
18.86
5vuqB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 5vuqA-4zvaA:
undetectable
5vuqB-4zvaA:
undetectable		 5vuqA-4zvaA:
18.86
5vuqB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 5vurA-4zvaA:
undetectable
5vurB-4zvaA:
2.2		 5vurA-4zvaA:
18.86
5vurB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.26A 5vusA-4zvaA:
undetectable
5vusB-4zvaA:
undetectable		 5vusA-4zvaA:
18.86
5vusB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 5vusA-4zvaA:
undetectable
5vusB-4zvaA:
undetectable		 5vusA-4zvaA:
18.86
5vusB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 5vutA-4zvaA:
undetectable
5vutB-4zvaA:
undetectable		 5vutA-4zvaA:
18.86
5vutB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 5vutA-4zvaA:
undetectable
5vutB-4zvaA:
undetectable		 5vutA-4zvaA:
18.86
5vutB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.27A 5vuuA-4zvaA:
undetectable
5vuuB-4zvaA:
undetectable		 5vuuA-4zvaA:
18.86
5vuuB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 5vuuA-4zvaA:
undetectable
5vuuB-4zvaA:
undetectable		 5vuuA-4zvaA:
18.86
5vuuB-4zvaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 5vuwA-4zvaA:
undetectable
5vuwB-4zvaA:
undetectable		 5vuwA-4zvaA:
18.56
5vuwB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.44A 5vuwA-4zvaA:
undetectable
5vuwB-4zvaA:
undetectable		 5vuwA-4zvaA:
18.56
5vuwB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 5vuxA-4zvaA:
undetectable
5vuxB-4zvaA:
undetectable		 5vuxA-4zvaA:
18.56
5vuxB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.30A 5vuyA-4zvaA:
2.1
5vuyB-4zvaA:
undetectable		 5vuyA-4zvaA:
18.56
5vuyB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 5vuyA-4zvaA:
2.1
5vuyB-4zvaA:
undetectable		 5vuyA-4zvaA:
18.56
5vuyB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.40A 5vuzA-4zvaA:
undetectable
5vuzB-4zvaA:
undetectable		 5vuzA-4zvaA:
18.56
5vuzB-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 5vv2A-4zvaA:
undetectable
5vv2B-4zvaA:
2.1		 5vv2A-4zvaA:
18.56
5vv2B-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.42A 5vv2A-4zvaA:
undetectable
5vv2B-4zvaA:
2.1		 5vv2A-4zvaA:
18.56
5vv2B-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.29A 5vv5A-4zvaA:
undetectable
5vv5B-4zvaA:
2.0		 5vv5A-4zvaA:
18.56
5vv5B-4zvaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.28A 6ausA-4zvaA:
undetectable
6ausB-4zvaA:
undetectable		 6ausA-4zvaA:
21.88
6ausB-4zvaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.40A 6ausA-4zvaA:
undetectable
6ausB-4zvaA:
undetectable		 6ausA-4zvaA:
21.88
6ausB-4zvaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.41A 6auvA-4zvaA:
undetectable
6auvB-4zvaA:
undetectable		 6auvA-4zvaA:
21.88
6auvB-4zvaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 6auwA-4zvaA:
1.4
6auwB-4zvaA:
undetectable		 6auwA-4zvaA:
21.88
6auwB-4zvaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.40A 6auwA-4zvaA:
1.4
6auwB-4zvaA:
undetectable		 6auwA-4zvaA:
21.88
6auwB-4zvaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 6auxA-4zvaA:
undetectable
6auxB-4zvaA:
undetectable		 6auxA-4zvaA:
21.88
6auxB-4zvaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 6auxA-4zvaA:
undetectable
6auxB-4zvaA:
undetectable		 6auxA-4zvaA:
21.88
6auxB-4zvaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 6auyA-4zvaA:
undetectable
6auyB-4zvaA:
2.1		 6auyA-4zvaA:
20.62
6auyB-4zvaA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.39A 6av0A-4zvaA:
undetectable
6av0B-4zvaA:
2.1		 6av0A-4zvaA:
20.62
6av0B-4zvaA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 6av2A-4zvaA:
undetectable
6av2B-4zvaA:
undetectable		 6av2A-4zvaA:
20.62
6av2B-4zvaA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.43A 6av3A-4zvaA:
1.2
6av3B-4zvaA:
undetectable		 6av3A-4zvaA:
20.62
6av3B-4zvaA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zva DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.38A 6av4A-4zvaA:
undetectable
6av4B-4zvaA:
undetectable		 6av4A-4zvaA:
20.62
6av4B-4zvaA:
20.62