SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zvb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.47A 1lzxA-4zvbA:
2.1
1lzxB-4zvbA:
undetectable		 1lzxA-4zvbA:
16.67
1lzxB-4zvbA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.45A 1lzzA-4zvbA:
undetectable
1lzzB-4zvbA:
undetectable		 1lzzA-4zvbA:
16.67
1lzzB-4zvbA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 1m00A-4zvbA:
undetectable
1m00B-4zvbA:
undetectable		 1m00A-4zvbA:
16.67
1m00B-4zvbA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 1mmvA-4zvbA:
undetectable
1mmvB-4zvbA:
undetectable		 1mmvA-4zvbA:
16.67
1mmvB-4zvbA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.38A 1mmvA-4zvbA:
undetectable
1mmvB-4zvbA:
undetectable		 1mmvA-4zvbA:
16.67
1mmvB-4zvbA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.46A 1om4A-4zvbA:
undetectable
1om4B-4zvbA:
undetectable		 1om4A-4zvbA:
17.06
1om4B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.47A 1p6jA-4zvbA:
undetectable
1p6jB-4zvbA:
undetectable		 1p6jA-4zvbA:
17.10
1p6jB-4zvbA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.45A 1rs7A-4zvbA:
undetectable
1rs7B-4zvbA:
undetectable		 1rs7A-4zvbA:
17.10
1rs7B-4zvbA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.37A 2g6mA-4zvbA:
undetectable
2g6mB-4zvbA:
undetectable		 2g6mA-4zvbA:
16.63
2g6mB-4zvbA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 LEU A  15
ALA A  79
LEU A  77
ALA A  27
 None
 0.92A 2vcvG-4zvbA:
undetectable		 2vcvG-4zvbA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 3hsnA-4zvbA:
undetectable
3hsnB-4zvbA:
undetectable		 3hsnA-4zvbA:
17.06
3hsnB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 3hsoA-4zvbA:
undetectable
3hsoB-4zvbA:
undetectable		 3hsoA-4zvbA:
17.06
3hsoB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 3jt6A-4zvbA:
undetectable
3jt6B-4zvbA:
undetectable		 3jt6A-4zvbA:
17.06
3jt6B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 3jt7A-4zvbA:
undetectable
3jt7B-4zvbA:
undetectable		 3jt7A-4zvbA:
17.06
3jt7B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 3jt8A-4zvbA:
undetectable
3jt8B-4zvbA:
undetectable		 3jt8A-4zvbA:
17.06
3jt8B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.39A 3jtaA-4zvbA:
undetectable
3jtaB-4zvbA:
undetectable		 3jtaA-4zvbA:
17.06
3jtaB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.41A 3jtaA-4zvbA:
undetectable
3jtaB-4zvbA:
undetectable		 3jtaA-4zvbA:
17.06
3jtaB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 3jwsA-4zvbA:
undetectable
3jwsB-4zvbA:
undetectable		 3jwsA-4zvbA:
17.06
3jwsB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 3jwtA-4zvbA:
undetectable
3jwtB-4zvbA:
undetectable		 3jwtA-4zvbA:
17.06
3jwtB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 3jwtA-4zvbA:
undetectable
3jwtB-4zvbA:
undetectable		 3jwtA-4zvbA:
17.06
3jwtB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.31A 3jx0A-4zvbA:
undetectable
3jx0B-4zvbA:
undetectable		 3jx0A-4zvbA:
17.06
3jx0B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 3jx1A-4zvbA:
undetectable
3jx1B-4zvbA:
undetectable		 3jx1A-4zvbA:
17.06
3jx1B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		5 / 12 ALA A 147
LEU A  56
LEU A 115
GLY A 111
PHE A 112
 None
HEM  A 201 (-4.3A)
None
HEM  A 201 ( 4.2A)
HEM  A 201 (-3.6A)
 1.14A 3k2hA-4zvbA:
undetectable		 3k2hA-4zvbA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		5 / 12 ALA A 147
LEU A  56
LEU A 115
GLY A 111
PHE A 112
 None
HEM  A 201 (-4.3A)
None
HEM  A 201 ( 4.2A)
HEM  A 201 (-3.6A)
 1.11A 3k2hB-4zvbA:
undetectable		 3k2hB-4zvbA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.46A 3n2rA-4zvbA:
undetectable
3n2rB-4zvbA:
undetectable		 3n2rA-4zvbA:
17.06
3n2rB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.45A 3n2rA-4zvbA:
undetectable
3n2rB-4zvbA:
undetectable		 3n2rA-4zvbA:
17.06
3n2rB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.42A 3n5vA-4zvbA:
undetectable
3n5vB-4zvbA:
undetectable		 3n5vA-4zvbA:
17.06
3n5vB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 3n5yA-4zvbA:
1.6
3n5yB-4zvbA:
undetectable		 3n5yA-4zvbA:
17.06
3n5yB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 3n5zA-4zvbA:
undetectable
3n5zB-4zvbA:
undetectable		 3n5zA-4zvbA:
17.06
3n5zB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 3nlkA-4zvbA:
undetectable
3nlkB-4zvbA:
undetectable		 3nlkA-4zvbA:
17.06
3nlkB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.35A 3nloA-4zvbA:
undetectable
3nloB-4zvbA:
undetectable		 3nloA-4zvbA:
17.06
3nloB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 3nlvA-4zvbA:
undetectable
3nlvB-4zvbA:
undetectable		 3nlvA-4zvbA:
17.06
3nlvB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.39A 3nnyA-4zvbA:
undetectable
3nnyB-4zvbA:
undetectable		 3nnyA-4zvbA:
17.06
3nnyB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.38A 3pneA-4zvbA:
1.9
3pneB-4zvbA:
undetectable		 3pneA-4zvbA:
17.06
3pneB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.39A 3pngA-4zvbA:
undetectable
3pngB-4zvbA:
undetectable		 3pngA-4zvbA:
17.06
3pngB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 3q99A-4zvbA:
undetectable
3q99B-4zvbA:
undetectable		 3q99A-4zvbA:
17.06
3q99B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.46A 3q99A-4zvbA:
undetectable
3q99B-4zvbA:
undetectable		 3q99A-4zvbA:
17.06
3q99B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 3q9aA-4zvbA:
undetectable
3q9aB-4zvbA:
undetectable		 3q9aA-4zvbA:
17.06
3q9aB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 3rqlA-4zvbA:
1.9
3rqlB-4zvbA:
undetectable		 3rqlA-4zvbA:
17.06
3rqlB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.39A 3rqnA-4zvbA:
undetectable
3rqnB-4zvbA:
undetectable		 3rqnA-4zvbA:
17.06
3rqnB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 3tynA-4zvbA:
undetectable
3tynB-4zvbA:
undetectable		 3tynA-4zvbA:
17.06
3tynB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.45A 3tyoA-4zvbA:
undetectable
3tyoB-4zvbA:
undetectable		 3tyoA-4zvbA:
17.06
3tyoB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.42A 3ufoA-4zvbA:
undetectable
3ufoB-4zvbA:
undetectable		 3ufoA-4zvbA:
17.06
3ufoB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.45A 3ufsA-4zvbA:
undetectable
3ufsB-4zvbA:
undetectable		 3ufsA-4zvbA:
17.06
3ufsB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.38A 3ufuA-4zvbA:
undetectable
3ufuB-4zvbA:
undetectable		 3ufuA-4zvbA:
17.06
3ufuB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 3ufvA-4zvbA:
undetectable
3ufvB-4zvbA:
undetectable		 3ufvA-4zvbA:
17.06
3ufvB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 8 LEU A 115
VAL A  76
LEU A  77
ALA A  35
 None
 0.87A 3uniB-4zvbA:
undetectable		 3uniB-4zvbA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4camA-4zvbA:
undetectable
4camB-4zvbA:
undetectable		 4camA-4zvbA:
17.06
4camB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.44A 4camA-4zvbA:
undetectable
4camB-4zvbA:
undetectable		 4camA-4zvbA:
17.06
4camB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.43A 4canA-4zvbA:
undetectable
4canB-4zvbA:
undetectable		 4canA-4zvbA:
17.06
4canB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.44A 4canA-4zvbA:
undetectable
4canB-4zvbA:
undetectable		 4canA-4zvbA:
17.06
4canB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4caoA-4zvbA:
undetectable
4caoB-4zvbA:
undetectable		 4caoA-4zvbA:
17.06
4caoB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 4capA-4zvbA:
undetectable
4capB-4zvbA:
undetectable		 4capA-4zvbA:
17.06
4capB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4caqA-4zvbA:
undetectable
4caqB-4zvbA:
undetectable		 4caqA-4zvbA:
17.06
4caqB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4cdtA-4zvbA:
undetectable
4cdtB-4zvbA:
undetectable		 4cdtA-4zvbA:
17.06
4cdtB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 4ctpA-4zvbA:
undetectable
4ctpB-4zvbA:
undetectable		 4ctpA-4zvbA:
17.06
4ctpB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 4ctrA-4zvbA:
undetectable
4ctrB-4zvbA:
1.8		 4ctrA-4zvbA:
17.06
4ctrB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.40A 4ctrA-4zvbA:
undetectable
4ctrB-4zvbA:
1.8		 4ctrA-4zvbA:
17.06
4ctrB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 4cttA-4zvbA:
undetectable
4cttB-4zvbA:
undetectable		 4cttA-4zvbA:
17.06
4cttB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 4ctuA-4zvbA:
undetectable
4ctuB-4zvbA:
undetectable		 4ctuA-4zvbA:
17.06
4ctuB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 4ctvA-4zvbA:
undetectable
4ctvB-4zvbA:
undetectable		 4ctvA-4zvbA:
17.06
4ctvB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 4ctwA-4zvbA:
undetectable
4ctwB-4zvbA:
undetectable		 4ctwA-4zvbA:
17.06
4ctwB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4ctxA-4zvbA:
undetectable
4ctxB-4zvbA:
undetectable		 4ctxA-4zvbA:
17.06
4ctxB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.43A 4ctxA-4zvbA:
undetectable
4ctxB-4zvbA:
undetectable		 4ctxA-4zvbA:
17.06
4ctxB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4cx5A-4zvbA:
undetectable
4cx5B-4zvbA:
undetectable		 4cx5A-4zvbA:
17.06
4cx5B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.36A 4cx5A-4zvbA:
undetectable
4cx5B-4zvbA:
undetectable		 4cx5A-4zvbA:
17.06
4cx5B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 4d1nA-4zvbA:
undetectable
4d1nB-4zvbA:
undetectable		 4d1nA-4zvbA:
17.58
4d1nB-4zvbA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 4d1nA-4zvbA:
undetectable
4d1nB-4zvbA:
undetectable		 4d1nA-4zvbA:
17.58
4d1nB-4zvbA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 4d2yA-4zvbA:
undetectable
4d2yB-4zvbA:
undetectable		 4d2yA-4zvbA:
17.06
4d2yB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.48A 4d31A-4zvbA:
undetectable
4d31B-4zvbA:
undetectable		 4d31A-4zvbA:
17.06
4d31B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4d3bA-4zvbA:
2.2
4d3bB-4zvbA:
undetectable		 4d3bA-4zvbA:
17.06
4d3bB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4d7oA-4zvbA:
undetectable
4d7oB-4zvbA:
2.2		 4d7oA-4zvbA:
17.06
4d7oB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 4euxA-4zvbA:
undetectable
4euxB-4zvbA:
2.2		 4euxA-4zvbA:
17.06
4euxB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 4fvwA-4zvbA:
undetectable
4fvwB-4zvbA:
1.8		 4fvwA-4zvbA:
17.06
4fvwB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.48A 4fvwA-4zvbA:
undetectable
4fvwB-4zvbA:
1.8		 4fvwA-4zvbA:
17.06
4fvwB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 4jsgA-4zvbA:
undetectable
4jsgB-4zvbA:
undetectable		 4jsgA-4zvbA:
17.06
4jsgB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.34A 4jsjA-4zvbA:
undetectable
4jsjB-4zvbA:
undetectable		 4jsjA-4zvbA:
17.06
4jsjB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 4k5fA-4zvbA:
undetectable
4k5fB-4zvbA:
undetectable		 4k5fA-4zvbA:
17.06
4k5fB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.39A 4k5gA-4zvbA:
undetectable
4k5gB-4zvbA:
undetectable		 4k5gA-4zvbA:
17.06
4k5gB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.47A 4kciA-4zvbA:
undetectable
4kciB-4zvbA:
undetectable		 4kciA-4zvbA:
17.06
4kciB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.45A 4kcjA-4zvbA:
undetectable
4kcjB-4zvbA:
undetectable		 4kcjA-4zvbA:
17.06
4kcjB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.33A 4kckA-4zvbA:
undetectable
4kckB-4zvbA:
undetectable		 4kckA-4zvbA:
17.06
4kckB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.42A 4kckA-4zvbA:
undetectable
4kckB-4zvbA:
undetectable		 4kckA-4zvbA:
17.06
4kckB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 4kcmA-4zvbA:
undetectable
4kcmB-4zvbA:
undetectable		 4kcmA-4zvbA:
17.06
4kcmB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.47A 4luxA-4zvbA:
undetectable
4luxB-4zvbA:
undetectable		 4luxA-4zvbA:
17.06
4luxB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 4uchA-4zvbA:
undetectable
4uchB-4zvbA:
undetectable		 4uchA-4zvbA:
17.49
4uchB-4zvbA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4uh0A-4zvbA:
undetectable
4uh0B-4zvbA:
undetectable		 4uh0A-4zvbA:
17.06
4uh0B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4uh1A-4zvbA:
undetectable
4uh1B-4zvbA:
undetectable		 4uh1A-4zvbA:
17.06
4uh1B-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.42A 4uh6A-4zvbA:
undetectable
4uh6B-4zvbA:
2.0		 4uh6A-4zvbA:
17.54
4uh6B-4zvbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 4upmA-4zvbA:
undetectable
4upmB-4zvbA:
undetectable		 4upmA-4zvbA:
17.06
4upmB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 4upnA-4zvbA:
undetectable
4upnB-4zvbA:
2.2		 4upnA-4zvbA:
17.06
4upnB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.32A 4uppA-4zvbA:
undetectable
4uppB-4zvbA:
undetectable		 4uppA-4zvbA:
17.06
4uppB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.40A 4v3uC-4zvbA:
1.9
4v3uD-4zvbA:
undetectable		 4v3uC-4zvbA:
17.58
4v3uD-4zvbA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.41A 5adgA-4zvbA:
undetectable
5adgB-4zvbA:
undetectable		 5adgA-4zvbA:
17.54
5adgB-4zvbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.46A 5fvtA-4zvbA:
undetectable
5fvtB-4zvbA:
undetectable		 5fvtA-4zvbA:
17.06
5fvtB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.44A 5unuA-4zvbA:
undetectable
5unuB-4zvbA:
undetectable		 5unuA-4zvbA:
17.06
5unuB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.42A 5unyA-4zvbA:
undetectable
5unyB-4zvbA:
undetectable		 5unyA-4zvbA:
17.06
5unyB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.42A 5unyA-4zvbA:
undetectable
5unyB-4zvbA:
undetectable		 5unyA-4zvbA:
17.06
5unyB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.44A 5unzA-4zvbA:
undetectable
5unzB-4zvbA:
undetectable		 5unzA-4zvbA:
17.06
5unzB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.38A 5uo4A-4zvbA:
undetectable
5uo4B-4zvbA:
undetectable		 5uo4A-4zvbA:
17.54
5uo4B-4zvbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.39A 5uo5A-4zvbA:
undetectable
5uo5B-4zvbA:
undetectable		 5uo5A-4zvbA:
17.54
5uo5B-4zvbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 5vulA-4zvbA:
1.9
5vulB-4zvbA:
undetectable		 5vulA-4zvbA:
17.06
5vulB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 5vulA-4zvbA:
1.9
5vulB-4zvbA:
undetectable		 5vulA-4zvbA:
17.06
5vulB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.37A 5vunA-4zvbA:
undetectable
5vunB-4zvbA:
undetectable		 5vunA-4zvbA:
17.06
5vunB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.47A 5vunA-4zvbA:
undetectable
5vunB-4zvbA:
undetectable		 5vunA-4zvbA:
17.06
5vunB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.49A 5vuoA-4zvbA:
2.2
5vuoB-4zvbA:
undetectable		 5vuoA-4zvbA:
17.06
5vuoB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.48A 5vuoA-4zvbA:
2.2
5vuoB-4zvbA:
undetectable		 5vuoA-4zvbA:
17.06
5vuoB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.34A 5vupA-4zvbA:
undetectable
5vupB-4zvbA:
undetectable		 5vupA-4zvbA:
17.06
5vupB-4zvbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 5vuyA-4zvbA:
2.2
5vuyB-4zvbA:
undetectable		 5vuyA-4zvbA:
17.54
5vuyB-4zvbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 5vuzA-4zvbA:
undetectable
5vuzB-4zvbA:
undetectable		 5vuzA-4zvbA:
17.54
5vuzB-4zvbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.44A 5vv3A-4zvbA:
2.2
5vv3B-4zvbA:
undetectable		 5vv3A-4zvbA:
17.54
5vv3B-4zvbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.35A 5vv5A-4zvbA:
1.7
5vv5B-4zvbA:
2.2		 5vv5A-4zvbA:
17.54
5vv5B-4zvbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.43A 6aurA-4zvbA:
undetectable
6aurB-4zvbA:
undetectable		 6aurA-4zvbA:
20.99
6aurB-4zvbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.48A 6auwA-4zvbA:
undetectable
6auwB-4zvbA:
undetectable		 6auwA-4zvbA:
20.99
6auwB-4zvbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.42A 6auxA-4zvbA:
undetectable
6auxB-4zvbA:
undetectable		 6auxA-4zvbA:
20.99
6auxB-4zvbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.40A 6av1A-4zvbA:
undetectable
6av1B-4zvbA:
undetectable		 6av1A-4zvbA:
19.75
6av1B-4zvbA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.46A 6av2A-4zvbA:
undetectable
6av2B-4zvbA:
undetectable		 6av2A-4zvbA:
19.75
6av2B-4zvbA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.43A 6av5A-4zvbA:
undetectable
6av5B-4zvbA:
undetectable		 6av5A-4zvbA:
19.75
6av5B-4zvbA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 6cicA-4zvbA:
undetectable
6cicB-4zvbA:
undetectable		 6cicA-4zvbA:
19.75
6cicB-4zvbA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 MET A   8
VAL A  84
TRP A  12
GLU A  11
 None
 1.36A 6cidA-4zvbA:
2.3
6cidB-4zvbA:
2.1		 6cidA-4zvbA:
19.75
6cidB-4zvbA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zvb DIGUANYLATE CYCLASE
DOSC
(Escherichia
coli) 		4 / 7 TRP A  12
GLU A  11
MET A   8
VAL A  84
 None
 1.39A 6cidA-4zvbA:
2.3
6cidB-4zvbA:
2.1		 6cidA-4zvbA:
19.75
6cidB-4zvbA:
19.75