SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zw0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		5 / 11 ILE A  97
MET A  72
ILE A  68
ALA A 140
ALA A 142
 None
 1.19A 2qhfA-4zw0A:
undetectable		 2qhfA-4zw0A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		4 / 8 VAL A  28
LEU A  15
LEU A  19
ILE A  79
 None
 0.85A 3u5kA-4zw0A:
undetectable		 3u5kA-4zw0A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		4 / 8 VAL A  28
LEU A  15
LEU A  19
ILE A  79
 None
 0.87A 3u5kC-4zw0A:
undetectable		 3u5kC-4zw0A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		4 / 8 VAL A  28
LEU A  15
LEU A  19
ILE A  79
 None
 0.83A 3u5kD-4zw0A:
undetectable		 3u5kD-4zw0A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		3 / 3 ASN A  84
ASP A  37
ASN A 121
 None
 0.78A 4agaA-4zw0A:
undetectable		 4agaA-4zw0A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		4 / 5 PHE A  86
PRO A  92
VAL A 148
ALA A  81
 None
 1.09A 4w5oA-4zw0A:
undetectable		 4w5oA-4zw0A:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		4 / 5 PHE A  86
PRO A  92
VAL A 148
ALA A  81
 None
 1.09A 4z4cA-4zw0A:
undetectable		 4z4cA-4zw0A:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		4 / 5 PHE A  86
PRO A  92
VAL A 148
ALA A  81
 None
 1.11A 4z4dA-4zw0A:
undetectable		 4z4dA-4zw0A:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		4 / 5 PHE A  86
PRO A  92
VAL A 148
ALA A  81
 None
 1.10A 4z4eA-4zw0A:
undetectable		 4z4eA-4zw0A:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		5 / 12 ALA A 132
GLY A  71
GLY A  65
LEU A  67
ALA A  76
 None
 1.13A 5c0oE-4zw0A:
undetectable		 5c0oE-4zw0A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		4 / 7 VAL A  31
ILE A  34
VAL A 116
ALA A  40
 None
 0.64A 5osrA-4zw0A:
undetectable		 5osrA-4zw0A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ
(Candidatus
Liberibacter
asiaticus) 		4 / 6 PHE A  86
PRO A  92
VAL A 148
ALA A  81
 None
 1.07A 5t7bA-4zw0A:
undetectable		 5t7bA-4zw0A:
11.06