SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zws'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IKE_A_HSMA190_1 (NITROPHORIN 4)	4zws	RECOMBINATION PROTEIN UVSY (Escherichia virus T4)	3 / 3	ASP A 13 LEU A 6 LEU A 10	None	0.55A	1ikeA-4zwsA: undetectable	1ikeA-4zwsA: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XZ1_A_HLTA2001_1 (FERRITIN LIGHT CHAIN)	4zws	RECOMBINATION PROTEIN UVSY (Escherichia virus T4)	4 / 4	LEU A 61 SER A 65 TYR A 64 LEU A 87	None	1.25A	1xz1A-4zwsA: 4.2	1xz1A-4zwsA: 25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XZ3_A_ICFA201_1 (FERRITIN LIGHT CHAIN)	4zws	RECOMBINATION PROTEIN UVSY (Escherichia virus T4)	4 / 4	LEU A 61 SER A 65 TYR A 64 LEU A 87	None	1.27A	1xz3A-4zwsA: 4.2	1xz3A-4zwsA: 25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKD_B_CYZB267_2 (GLUTAMATE RECEPTOR 2)	4zws	RECOMBINATION PROTEIN UVSY (Escherichia virus T4)	5 / 9	LEU A 107 SER A 111 LEU A 114 ASP A 115 LYS A 118	None	0.98A	3tkdB-4zwsA: undetectable	3tkdB-4zwsA: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5PHH_A_LDPA414_1 (LYSINE-SPECIFIC DEMETHYLASE 4D)	4zws	RECOMBINATION PROTEIN UVSY (Escherichia virus T4)	4 / 6	GLU A 24 ARG A 120 ALA A 25 LEU A 21	None	1.13A	5phhA-4zwsA: undetectable	5phhA-4zwsA: 17.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IKE_A_HSMA190_1","NITROPHORIN 4","4zws","RECOMBINATION PROTEIN UVSY","Escherichia virus T4",3,"ASP A  13;LEU A   6;LEU A  10","None","0.55A","1ikeA-4zwsA:undetectable","1ikeA-4zwsA:19.02"],["1XZ1_A_HLTA2001_1","FERRITIN LIGHT CHAIN","4zws","RECOMBINATION PROTEIN UVSY","Escherichia virus T4",4,"LEU A  61;SER A  65;TYR A  64;LEU A  87","None","1.25A","1xz1A-4zwsA:4.2","1xz1A-4zwsA:25.14"],["1XZ3_A_ICFA201_1","FERRITIN LIGHT CHAIN","4zws","RECOMBINATION PROTEIN UVSY","Escherichia virus T4",4,"LEU A  61;SER A  65;TYR A  64;LEU A  87","None","1.27A","1xz3A-4zwsA:4.2","1xz3A-4zwsA:25.14"],["3TKD_B_CYZB267_2","GLUTAMATE RECEPTOR 2","4zws","RECOMBINATION PROTEIN UVSY","Escherichia virus T4",5,"LEU A 107;SER A 111;LEU A 114;ASP A 115;LYS A 118","None","0.98A","3tkdB-4zwsA:undetectable","3tkdB-4zwsA:21.14"],["5PHH_A_LDPA414_1","LYSINE-SPECIFIC DEMETHYLASE 4D","4zws","RECOMBINATION PROTEIN UVSY","Escherichia virus T4",4,"GLU A  24;ARG A 120;ALA A  25;LEU A  21","None","1.13A","5phhA-4zwsA:undetectable","5phhA-4zwsA:17.22"]]