SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zxc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 5 TYR A  31
ILE W 287
ARG W 284
GLY W 276
 None
 1.18A 1kifA-4zxcA:
undetectable		 1kifA-4zxcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 5 TYR A  31
ILE W 287
ARG W 284
GLY W 276
 None
 1.18A 1kifB-4zxcA:
undetectable		 1kifB-4zxcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 5 TYR A  31
ILE W 287
ARG W 284
GLY W 276
 None
 1.18A 1kifC-4zxcA:
undetectable		 1kifC-4zxcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 5 TYR A  31
ILE W 287
ARG W 284
GLY W 276
 None
 1.18A 1kifD-4zxcA:
undetectable		 1kifD-4zxcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 5 TYR A  31
ILE W 287
ARG W 284
GLY W 276
 None
 1.18A 1kifE-4zxcA:
undetectable		 1kifE-4zxcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 5 TYR A  31
ILE W 287
ARG W 284
GLY W 276
 None
 1.18A 1kifF-4zxcA:
undetectable		 1kifF-4zxcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 5 TYR A  31
ILE W 287
ARG W 284
GLY W 276
 None
 1.18A 1kifG-4zxcA:
undetectable		 1kifG-4zxcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 5 TYR A  31
ILE W 287
ARG W 284
GLY W 276
 None
 1.18A 1kifH-4zxcA:
undetectable		 1kifH-4zxcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 5 TYR A  31
ILE W 287
ARG W 284
GLY W 276
 None
 1.18A 1ve9A-4zxcA:
undetectable		 1ve9A-4zxcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 8 TYR W  95
TYR W 101
HIS W 256
GLY W 257
 None
None
FE  W 500 (-3.1A)
None
 1.13A 2ha4A-4zxcW:
undetectable		 2ha4A-4zxcW:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 7 TYR W  95
TYR W 101
HIS W 256
GLY W 257
 None
None
FE  W 500 (-3.1A)
None
 1.16A 2ha4B-4zxcW:
undetectable		 2ha4B-4zxcW:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		3 / 3 ASN W 158
ASN W 138
ARG W  41
 None
 0.91A 2rlcA-4zxcW:
undetectable		 2rlcA-4zxcW:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		5 / 11 ALA A  73
ALA A 130
GLY A 131
SER A 132
ARG W 174
 None
 1.47A 2xfsB-4zxcA:
undetectable		 2xfsB-4zxcA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_A_ACTA601_0
(CHOLINE OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 5 ILE W  61
HIS W  59
VAL W  88
HIS W  87
 None
 1.38A 3nneA-4zxcW:
undetectable		 3nneA-4zxcW:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_B_ACTB601_0
(CHOLINE OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 5 ILE W  61
HIS W  59
VAL W  88
HIS W  87
 None
 1.35A 3nneB-4zxcW:
undetectable		 3nneB-4zxcW:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_E_ACTE601_0
(CHOLINE OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		4 / 4 TRP W 316
ILE W 265
TRP W 263
VAL A  51
 None
 1.18A 3nneE-4zxcW:
0.0		 3nneE-4zxcW:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 7 LEU W 326
LYS W 333
LEU A  55
TYR W 327
 None
 1.10A 4b3qA-4zxcW:
undetectable		 4b3qA-4zxcW:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3;
Pseudomonas
sp.
WBC-3) 		5 / 12 HIS A  30
PRO W 298
TRP W 263
PHE W 339
GLY A  52
 None
 1.33A 4hvcA-4zxcA:
undetectable		 4hvcA-4zxcA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 7 HIS W 256
GLU W 262
HIS W 303
VAL W 315
 FE  W 500 (-3.1A)
FE  W 500 (-2.1A)
FE  W 500 (-3.1A)
None
 0.72A 4hvrA-4zxcW:
8.6		 4hvrA-4zxcW:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 8 SER A  34
CYH A 162
PHE W 339
TRP A 158
 None
 1.12A 4j7uD-4zxcA:
undetectable		 4j7uD-4zxcA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 7 ASN W 191
ARG W 310
VAL W 228
ARG W 167
 None
 1.36A 4mv7A-4zxcW:
undetectable		 4mv7A-4zxcW:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 8 ILE W  48
PHE W 129
LEU W  39
PHE W 120
 None
 0.76A 4qopC-4zxcW:
undetectable		 4qopC-4zxcW:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 5 ALA W  75
HIS W  87
PRO W 253
PHE W  85
 None
 1.39A 4ze2A-4zxcW:
undetectable		 4ze2A-4zxcW:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 6 ILE W 337
PRO W 336
ILE W 287
VAL A  21
 None
 0.99A 4zj8A-4zxcW:
undetectable		 4zj8A-4zxcW:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 6 ILE W 251
PHE W 250
ARG W  68
ILE W  65
 None
 1.17A 4zzcA-4zxcW:
undetectable
4zzcB-4zxcW:
undetectable		 4zzcA-4zxcW:
21.51
4zzcB-4zxcW:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4zxc HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 6 SER A 132
ALA A 133
MET A 115
LEU A 128
 None
 1.26A 5dzkB-4zxcA:
undetectable
5dzkP-4zxcA:
undetectable		 5dzkB-4zxcA:
19.64
5dzkP-4zxcA:
1.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 8 HIS W  59
LEU W 100
GLY W  90
VAL W  88
 None
 1.01A 5m8rC-4zxcW:
undetectable		 5m8rC-4zxcW:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 4 HIS W 303
HIS W 256
TYR W  80
GLU W 262
 FE  W 500 (-3.1A)
FE  W 500 (-3.1A)
None
FE  W 500 (-2.1A)
 1.46A 5pahA-4zxcW:
undetectable		 5pahA-4zxcW:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 4zxc HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
(Pseudomonas
sp.
WBC-3) 		4 / 5 PHE W 144
VAL W  83
PRO W 232
VAL W 228
 None
 1.36A 6ekzA-4zxcW:
undetectable		 6ekzA-4zxcW:
13.72