SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zxg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4zxg GLUTATHIONE
S-TRANSFERASE
(Plasmodium
falciparum) 		4 / 6 ARG A  20
ALA A  16
ILE A  75
PRO A  60
 None
 1.22A 1oniB-4zxgA:
undetectable
1oniC-4zxgA:
undetectable		 1oniB-4zxgA:
22.95
1oniC-4zxgA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4zxg GLUTATHIONE
S-TRANSFERASE
(Plasmodium
falciparum) 		4 / 6 ARG A  13
GLY A  14
ALA A  16
HIS A 107
 None
 0.96A 1wmqA-4zxgA:
undetectable		 1wmqA-4zxgA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4zxg GLUTATHIONE
S-TRANSFERASE
(Plasmodium
falciparum) 		4 / 6 ARG A  13
GLY A  14
ALA A  16
HIS A 107
 None
 0.96A 1wmqB-4zxgA:
undetectable		 1wmqB-4zxgA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4zxg GLUTATHIONE
S-TRANSFERASE
(Plasmodium
falciparum) 		4 / 6 ARG A  13
GLY A  14
ALA A  16
HIS A 107
 None
 0.96A 1wpuA-4zxgA:
undetectable		 1wpuA-4zxgA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4zxg GLUTATHIONE
S-TRANSFERASE
(Plasmodium
falciparum) 		4 / 6 ARG A  13
GLY A  14
ALA A  16
HIS A 107
 None
 0.96A 1wpuB-4zxgA:
undetectable		 1wpuB-4zxgA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4zxg GLUTATHIONE
S-TRANSFERASE
(Plasmodium
falciparum) 		4 / 6 ARG A  13
GLY A  14
ALA A  16
HIS A 107
 None
 0.98A 1wrqA-4zxgA:
undetectable		 1wrqA-4zxgA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4zxg GLUTATHIONE
S-TRANSFERASE
(Plasmodium
falciparum) 		4 / 6 ARG A  13
GLY A  14
ALA A  16
HIS A 107
 None
 0.98A 1wrqB-4zxgA:
undetectable		 1wrqB-4zxgA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4zxg GLUTATHIONE
S-TRANSFERASE
(Plasmodium
falciparum) 		4 / 4 ALA A 161
VAL A 165
ASP A 162
LEU A 139
 None
 0.87A 4e7gA-4zxgA:
undetectable		 4e7gA-4zxgA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4zxg GLUTATHIONE
S-TRANSFERASE
(Plasmodium
falciparum) 		4 / 8 ASN A 190
VAL A 103
ILE A  99
PHE A 183
 None
 0.82A 4r38A-4zxgA:
undetectable		 4r38A-4zxgA:
19.52