SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zxl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 GLU A 186
TYR A 215
TYR A 213
PRO A 192
 None
 1.36A 1dfoB-4zxlA:
undetectable		 1dfoB-4zxlA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 GLU A 186
TYR A 215
TYR A 213
PRO A 192
 None
 1.35A 1dfoA-4zxlA:
undetectable		 1dfoA-4zxlA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 GLU A 186
TYR A 215
TYR A 213
PRO A 192
 None
 1.36A 1dfoD-4zxlA:
undetectable		 1dfoD-4zxlA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 GLU A 186
TYR A 215
TYR A 213
PRO A 192
 None
 1.35A 1dfoC-4zxlA:
undetectable		 1dfoC-4zxlA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 GLY A  59
ILE A 168
VAL A  55
SER A 137
 None
 1.10A 1rs7B-4zxlA:
undetectable		 1rs7B-4zxlA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 ASP A 474
GLU A 528
ARG A 495
 CD  A 715 (-2.2A)
None
None
 0.87A 1wopA-4zxlA:
undetectable		 1wopA-4zxlA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 VAL A 171
SER A 137
LEU A  46
PHE A 159
 None
 1.08A 2f78A-4zxlA:
undetectable		 2f78A-4zxlA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 VAL A 171
SER A 137
LEU A  46
PHE A 159
 None
 1.16A 2f78B-4zxlA:
undetectable		 2f78B-4zxlA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 VAL A 171
SER A 137
LEU A  46
PHE A 159
 None
 1.20A 2f8dA-4zxlA:
undetectable		 2f8dA-4zxlA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 GLY A 494
ARG A 484
TYR A 397
 None
 0.54A 2opxA-4zxlA:
undetectable		 2opxA-4zxlA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 ASN A  45
ARG A 462
ASP A 457
 None
 0.93A 2qe6A-4zxlA:
undetectable		 2qe6A-4zxlA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 ASN A  45
ARG A 462
ASP A 457
 None
 0.99A 2qe6B-4zxlA:
undetectable		 2qe6B-4zxlA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 GLU A 186
TYR A 215
TYR A 213
PRO A 192
 None
 1.46A 2vmyA-4zxlA:
undetectable		 2vmyA-4zxlA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 9 ILE A 361
PHE A 353
ALA A 354
VAL A 357
 None
 0.70A 2vufA-4zxlA:
2.8		 2vufA-4zxlA:
21.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W4X_A_STZA1591_1
(O-GLCNACASE BT_4395)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		7 / 11 ASP A 297
TYR A 335
THR A 366
VAL A 370
ASN A 396
ASP A 401
TYR A 402
 None
 0.71A 2w4xA-4zxlA:
48.3		 2w4xA-4zxlA:
31.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W4X_A_STZA1591_1
(O-GLCNACASE BT_4395)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		9 / 11 TYR A 335
THR A 366
VAL A 370
TRP A 394
ASN A 396
VAL A 399
ASP A 401
TYR A 402
ASN A 429
 None
 0.31A 2w4xA-4zxlA:
48.3		 2w4xA-4zxlA:
31.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_A_X0TA1625_1
(O-GLCNACASE NAGJ)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		6 / 12 LYS A 218
TYR A 295
ASN A 396
VAL A 399
ASP A 401
ASN A 429
 None
 0.92A 2x0yA-4zxlA:
54.3		 2x0yA-4zxlA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_A_X0TA1625_1
(O-GLCNACASE NAGJ)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		10 / 12 TYR A 295
ASP A 297
VAL A 331
TYR A 335
THR A 366
VAL A 370
ASN A 396
VAL A 399
ASP A 401
ASN A 429
 None
 0.61A 2x0yA-4zxlA:
54.3		 2x0yA-4zxlA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_A_X0TA1625_1
(O-GLCNACASE NAGJ)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		10 / 12 TYR A 295
VAL A 331
TYR A 335
THR A 366
VAL A 370
TRP A 394
ASN A 396
VAL A 399
ASP A 401
ASN A 429
 None
 0.48A 2x0yA-4zxlA:
54.3		 2x0yA-4zxlA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_B_X0TB1625_1
(O-GLCNACASE NAGJ)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		10 / 12 ASP A 297
VAL A 331
TYR A 335
THR A 366
ASN A 396
VAL A 399
ASP A 401
TYR A 402
ASN A 429
TRP A 490
 None
 0.47A 2x0yB-4zxlA:
54.3		 2x0yB-4zxlA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_B_X0TB1625_1
(O-GLCNACASE NAGJ)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		7 / 12 LYS A 218
ASN A 396
VAL A 399
ASP A 401
TYR A 402
ASN A 429
TRP A 490
 None
 0.76A 2x0yB-4zxlA:
54.3		 2x0yB-4zxlA:
99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_B_X0TB1625_1
(O-GLCNACASE NAGJ)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		10 / 12 VAL A 331
TYR A 335
THR A 366
TRP A 394
ASN A 396
VAL A 399
ASP A 401
TYR A 402
ASN A 429
TRP A 490
 None
 0.27A 2x0yB-4zxlA:
54.3		 2x0yB-4zxlA:
99.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.07A 2x45A-4zxlA:
undetectable		 2x45A-4zxlA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.10A 2x45B-4zxlA:
undetectable		 2x45B-4zxlA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.09A 2x45C-4zxlA:
undetectable		 2x45C-4zxlA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ILE A 441
MET A 431
PRO A 430
VAL A 608
 None
 1.17A 2ygoA-4zxlA:
undetectable		 2ygoA-4zxlA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.17A 3bu1A-4zxlA:
undetectable		 3bu1A-4zxlA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 12 VAL A 179
LEU A 419
ILE A 184
VAL A 423
ILE A 375
 None
 1.07A 3frqB-4zxlA:
undetectable		 3frqB-4zxlA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 GLU A 131
LYS A 326
THR A 212
ALA A 181
 None
CD  A 708 ( 4.2A)
None
None
 1.32A 3mbgA-4zxlA:
2.5
3mbgB-4zxlA:
2.6		 3mbgA-4zxlA:
12.22
3mbgB-4zxlA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 12 ILE A 299
ASP A 297
GLY A 338
ILE A 386
ILE A 383
 None
 1.06A 3pwwA-4zxlA:
undetectable		 3pwwA-4zxlA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9W_A_ACTA506_0
(GTPASE ERA)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 4 GLU A  84
GLU A 248
ASN A  77
PHE A 153
 None
 1.33A 3r9wA-4zxlA:
0.8		 3r9wA-4zxlA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 11 GLY A 190
GLU A 432
THR A 400
ARG A 198
GLY A 187
 None
 1.41A 3x2qA-4zxlA:
3.4
3x2qB-4zxlA:
undetectable
3x2qT-4zxlA:
undetectable		 3x2qA-4zxlA:
22.36
3x2qB-4zxlA:
18.15
3x2qT-4zxlA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 PRO A 368
GLY A 369
ASN A 373
GLU A 374
 None
 0.77A 3zqtA-4zxlA:
undetectable		 3zqtA-4zxlA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ARG A 502
LEU A 525
MET A 505
ASP A 506
 None
 1.44A 4cevA-4zxlA:
2.2
4cevB-4zxlA:
2.2		 4cevA-4zxlA:
19.57
4cevB-4zxlA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 MET A 505
ASP A 506
ARG A 502
LEU A 525
 None
 1.44A 4cevA-4zxlA:
2.2
4cevC-4zxlA:
2.3		 4cevA-4zxlA:
19.57
4cevC-4zxlA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ARG A 502
LEU A 525
MET A 505
ASP A 506
 None
 1.40A 4cevD-4zxlA:
2.4
4cevE-4zxlA:
2.2		 4cevD-4zxlA:
19.57
4cevE-4zxlA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ARG A 502
LEU A 525
MET A 505
ASP A 506
 None
 1.43A 4cevE-4zxlA:
2.2
4cevF-4zxlA:
2.2		 4cevE-4zxlA:
19.57
4cevF-4zxlA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 TYR A 133
THR A 158
GLU A 131
 None
 0.76A 4df3A-4zxlA:
2.5		 4df3A-4zxlA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 TYR A 133
THR A 158
GLU A 131
 None
 0.78A 4df3B-4zxlA:
undetectable		 4df3B-4zxlA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 PRO A 217
ILE A 257
TYR A 231
PHE A 255
 None
 1.15A 4g10A-4zxlA:
2.2		 4g10A-4zxlA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ASP A  75
ASP A 252
ASN A  77
ASP A 150
 None
CD  A 708 (-2.6A)
None
CD  A 708 (-3.6A)
 1.28A 4gkhJ-4zxlA:
undetectable		 4gkhJ-4zxlA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 GLY A 564
ALA A 616
SER A 568
GLU A 615
 None
 0.92A 4hyfA-4zxlA:
undetectable		 4hyfA-4zxlA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 8 GLY A 564
ALA A 616
SER A 568
GLU A 615
 None
 0.87A 4hyfC-4zxlA:
undetectable		 4hyfC-4zxlA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 8 ASN A 172
ASP A 117
LEU A 120
ILE A 105
 None
CD  A 706 ( 2.4A)
None
None
 1.08A 4l7iA-4zxlA:
undetectable		 4l7iA-4zxlA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 12 TYR A 295
VAL A 254
PHE A 425
GLY A 256
THR A 212
 None
 1.15A 4mm6A-4zxlA:
undetectable		 4mm6A-4zxlA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 10 LEU A 512
LEU A 525
ILE A 522
LEU A 521
LEU A 576
 None
 1.02A 4odoA-4zxlA:
undetectable		 4odoA-4zxlA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 10 LEU A 512
LEU A 525
ILE A 522
LEU A 521
LEU A 576
 None
 1.05A 4odoB-4zxlA:
undetectable		 4odoB-4zxlA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 10 LEU A 512
LEU A 525
ILE A 522
LEU A 521
LEU A 576
 None
 1.00A 4odoC-4zxlA:
undetectable		 4odoC-4zxlA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ALA A 125
LYS A 147
THR A 174
TYR A 176
 None
 1.36A 4w5qA-4zxlA:
2.9		 4w5qA-4zxlA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ALA A 125
LYS A 147
THR A 174
TYR A 176
 None
 1.38A 4w5rA-4zxlA:
2.4		 4w5rA-4zxlA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ALA A 125
LYS A 147
THR A 174
TYR A 176
 None
 1.37A 4w5tA-4zxlA:
2.4		 4w5tA-4zxlA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 PHE A 612
HIS A 481
MET A 505
LEU A 561
 None
 1.38A 5dzka-4zxlA:
2.2
5dzko-4zxlA:
undetectable		 5dzka-4zxlA:
15.38
5dzko-4zxlA:
0.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 PHE A 612
SER A 605
HIS A 481
LEU A 561
 None
 1.45A 5dzka-4zxlA:
2.2
5dzko-4zxlA:
undetectable		 5dzka-4zxlA:
15.38
5dzko-4zxlA:
0.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 12 ILE A 168
VAL A 136
ALA A 125
ALA A 134
GLY A 151
 None
 1.29A 5igpA-4zxlA:
undetectable		 5igpA-4zxlA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 TYR A 583
SER A 585
ALA A 586
GLN A 591
 None
 1.29A 5n4iA-4zxlA:
undetectable		 5n4iA-4zxlA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 4zxl O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 11 THR A 350
THR A 366
THR A 330
ILE A 361
VAL A 363
 None
 1.24A 6hcoA-4zxlA:
undetectable
6hcoB-4zxlA:
0.7		 6hcoA-4zxlA:
22.43
6hcoB-4zxlA:
22.43