SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zxo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 6 TRP A 195
ASP A 140
SER A 141
SER A 146
 None
 1.29A 1kiaC-4zxoA:
undetectable		 1kiaC-4zxoA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 TRP A 195
VAL A 126
ILE A 161
LEU A 217
VAL A 225
 None
 0.87A 1oipA-4zxoA:
2.3		 1oipA-4zxoA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		3 / 3 TRP A 196
PHE A 194
TRP A 136
 None
 1.46A 1r15C-4zxoA:
undetectable		 1r15C-4zxoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		3 / 3 TRP A 196
PHE A 194
TRP A 136
 None
 1.48A 1r15F-4zxoA:
undetectable		 1r15F-4zxoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		3 / 3 TRP A 196
PHE A 194
TRP A 136
 None
 1.49A 1r15G-4zxoA:
undetectable		 1r15G-4zxoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		3 / 3 TRP A 196
PHE A 194
TRP A 136
 None
 1.48A 1r15H-4zxoA:
undetectable		 1r15H-4zxoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_A_ADNA1501_1
(CLASS B ACID
PHOSPHATASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 10 ASP A 257
TYR A 206
THR A 291
GLY A 255
ARG A 184
 None
 1.40A 1rmtA-4zxoA:
1.7		 1rmtA-4zxoA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		3 / 3 ASP A 252
PHE A 183
ASN A 223
 None
 0.88A 1sg9B-4zxoA:
undetectable		 1sg9B-4zxoA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 5 TRP A 304
VAL A 322
THR A 293
ILE A 355
 None
 1.43A 1ss4A-4zxoA:
undetectable		 1ss4A-4zxoA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 8 TYR A 334
ASN A 325
ARG A 327
GLU A 328
 None
 1.10A 2fl5E-4zxoA:
undetectable
2fl5F-4zxoA:
undetectable		 2fl5E-4zxoA:
19.32
2fl5F-4zxoA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 PHE A 362
LEU A 321
ALA A  44
SER A 318
ASP A  56
 None
 1.25A 2iyfB-4zxoA:
undetectable		 2iyfB-4zxoA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 LEU A 277
GLY A 232
ASP A 236
ALA A 280
ILE A 276
 None
 0.98A 2nmyB-4zxoA:
undetectable		 2nmyB-4zxoA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 5 LEU A  37
LEU A  41
LEU A 254
MET A 119
 None
 1.08A 2oaxF-4zxoA:
undetectable		 2oaxF-4zxoA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 8 TRP A 136
ASP A  99
HIS A  54
ASP A  55
 None
 0.87A 2xadA-4zxoA:
undetectable		 2xadA-4zxoA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 8 TRP A 136
ASP A  99
HIS A  54
ASP A  55
 None
 0.85A 2xadB-4zxoA:
undetectable		 2xadB-4zxoA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 8 TRP A 136
ASP A  99
HIS A  54
ASP A  55
 None
 0.87A 2xadC-4zxoA:
undetectable		 2xadC-4zxoA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 6 TYR A 266
THR A 293
LEU A 308
VAL A 311
 None
 1.09A 2zuhA-4zxoA:
undetectable		 2zuhA-4zxoA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 6 TYR A 266
THR A 293
LEU A 308
VAL A 311
 None
 1.07A 2zuiA-4zxoA:
undetectable		 2zuiA-4zxoA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		3 / 3 GLU A 188
GLY A 191
THR A 190
 None
 0.58A 3iazA-4zxoA:
undetectable		 3iazA-4zxoA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 GLU A 292
GLY A 197
ASP A  86
GLY A  88
ASN A 128
 None
 0.88A 3jzjA-4zxoA:
undetectable		 3jzjA-4zxoA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 10 VAL A 358
GLY A 117
VAL A  72
ILE A 120
GLY A  81
 None
 1.14A 3km6A-4zxoA:
undetectable		 3km6A-4zxoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 8 ASN A  97
GLU A  64
TYR A 109
LEU A 106
 None
 1.13A 3rqwC-4zxoA:
undetectable
3rqwD-4zxoA:
undetectable		 3rqwC-4zxoA:
20.50
3rqwD-4zxoA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 8 GLU A  64
TYR A 109
LEU A 106
ASN A  97
 None
 1.11A 3rqwF-4zxoA:
undetectable
3rqwJ-4zxoA:
undetectable		 3rqwF-4zxoA:
20.50
3rqwJ-4zxoA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 TRP A 195
VAL A 126
ILE A 161
LEU A 217
VAL A 225
 None
 0.94A 3w67C-4zxoA:
undetectable		 3w67C-4zxoA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 TRP A 195
VAL A 126
LEU A  87
ILE A 161
LEU A 217
 None
 1.13A 3w67C-4zxoA:
undetectable		 3w67C-4zxoA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 TRP A 195
VAL A 126
ILE A 161
LEU A 217
VAL A 225
 None
 0.84A 3w68A-4zxoA:
undetectable		 3w68A-4zxoA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 TRP A 195
VAL A 126
LEU A  87
ILE A 161
LEU A 217
 None
 1.14A 3w68B-4zxoA:
undetectable		 3w68B-4zxoA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		6 / 12 TRP A 195
VAL A 126
VAL A 181
ILE A 161
LEU A 217
VAL A 225
 None
 1.01A 3w68B-4zxoA:
undetectable		 3w68B-4zxoA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 TRP A 195
VAL A 126
VAL A 181
ILE A 161
PHE A 167
 None
 1.02A 3w68B-4zxoA:
undetectable		 3w68B-4zxoA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		6 / 12 TRP A 195
VAL A 126
VAL A 181
ILE A 161
LEU A 217
VAL A 225
 None
 0.96A 3w68C-4zxoA:
1.6		 3w68C-4zxoA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		6 / 12 TRP A 195
VAL A 126
VAL A 181
ILE A 161
LEU A 217
VAL A 225
 None
 1.01A 3w68D-4zxoA:
undetectable		 3w68D-4zxoA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 TRP A 195
VAL A 126
VAL A 181
ILE A 161
PHE A 167
 None
 1.04A 3w68D-4zxoA:
undetectable		 3w68D-4zxoA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		3 / 3 ASP A  71
GLY A  62
TYR A 337
 None
 0.64A 3w9tC-4zxoA:
undetectable		 3w9tC-4zxoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		3 / 3 ASP A  71
GLY A  62
TYR A 337
 None
 0.65A 3w9tG-4zxoA:
undetectable		 3w9tG-4zxoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 12 VAL A 182
GLY A  81
GLY A  52
SER A  84
LEU A 356
 None
 1.05A 4qdjA-4zxoA:
undetectable		 4qdjA-4zxoA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 4 LEU A 209
MET A 148
VAL A 147
ASN A 153
 None
 1.06A 5b8iB-4zxoA:
undetectable		 5b8iB-4zxoA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 4 THR A 213
ASP A 215
ARG A 216
LEU A 217
 None
 1.27A 5tdmA-4zxoA:
1.4		 5tdmA-4zxoA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		5 / 9 VAL A 253
ILE A 312
LEU A 274
ARG A 184
ASP A 257
 None
 1.48A 6c2mC-4zxoA:
undetectable		 6c2mC-4zxoA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 6 GLY A  60
ASN A 325
SER A  70
ARG A  69
 None
 1.18A 6dwdA-4zxoA:
undetectable
6dwdC-4zxoA:
undetectable		 6dwdA-4zxoA:
21.65
6dwdC-4zxoA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 5 ARG A 116
ALA A 115
GLN A 113
ILE A 110
 None
 1.20A 6f6sA-4zxoA:
undetectable
6f6sB-4zxoA:
undetectable		 6f6sA-4zxoA:
13.24
6f6sB-4zxoA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 4zxo GLYCOSYL HYDROLASE
FAMILY 26
(Bacteroides
ovatus) 		4 / 5 GLY A 297
LEU A 295
SER A 342
GLN A 340
 None
 1.03A 6ji6A-4zxoA:
undetectable		 6ji6A-4zxoA:
23.86