SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 7 THR A 300
ASN A 334
GLY A 244
ASP A 293
 None
 0.99A 1bu5A-4zxzA:
undetectable		 1bu5A-4zxzA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 8 ARG A 388
VAL A 385
SER A 383
ASP A 206
 None
 0.87A 1hwiB-4zxzA:
undetectable		 1hwiB-4zxzA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 7 ARG A 388
VAL A 385
SER A 383
ASP A 206
 None
 0.96A 1hwiC-4zxzA:
undetectable		 1hwiC-4zxzA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 7 ARG A 388
VAL A 385
SER A 383
ASP A 206
 None
 0.96A 1hwiD-4zxzA:
undetectable		 1hwiD-4zxzA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 8 ARG A 388
VAL A 385
SER A 383
ASP A 206
 None
 0.96A 1hwkA-4zxzA:
undetectable		 1hwkA-4zxzA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 8 ARG A 388
VAL A 385
SER A 383
ASP A 206
 None
 0.94A 1hwkC-4zxzA:
undetectable		 1hwkC-4zxzA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 8 ARG A 388
VAL A 385
SER A 383
ASP A 206
 None
 0.94A 1hwkD-4zxzA:
undetectable		 1hwkD-4zxzA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		5 / 12 THR A 144
ILE A 149
GLY A 111
ILE A 140
GLU A 372
 None
 0.91A 1nv8B-4zxzA:
undetectable		 1nv8B-4zxzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		5 / 12 THR A 144
ILE A 149
GLY A 111
ILE A 140
GLU A 372
 None
 0.93A 1sg9B-4zxzA:
undetectable		 1sg9B-4zxzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		5 / 12 THR A 144
ILE A 149
GLY A 111
ILE A 140
GLU A 372
 None
 0.87A 1vq1B-4zxzA:
undetectable		 1vq1B-4zxzA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		5 / 9 THR A 205
LEU A 204
HIS A 167
ALA A 168
LEU A 369
 None
 1.24A 2azqA-4zxzA:
undetectable		 2azqA-4zxzA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		5 / 11 ILE A 190
GLU A 362
THR A 116
HIS A 113
GLY A 269
 None
 1.43A 2fn1A-4zxzA:
undetectable		 2fn1A-4zxzA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		5 / 11 ILE A 190
GLU A 362
THR A 116
HIS A 113
GLY A 269
 None
 1.45A 2fn1B-4zxzA:
undetectable		 2fn1B-4zxzA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 8 ALA A 191
VAL A 218
THR A 217
THR A 300
 None
 0.76A 2kotB-4zxzA:
undetectable		 2kotB-4zxzA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		5 / 12 ILE A 187
GLY A 329
ILE A 220
ASP A 235
GLY A 216
 None
 1.02A 3bwcA-4zxzA:
undetectable		 3bwcA-4zxzA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 6 ILE A 107
ALA A 109
ALA A 141
THR A 144
 None
 1.01A 3mdrB-4zxzA:
undetectable		 3mdrB-4zxzA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		6 / 9 VAL A 405
SER A 404
ILE A 107
ALA A 109
ALA A 141
THR A 144
 None
 1.25A 3mdtA-4zxzA:
undetectable		 3mdtA-4zxzA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		3 / 3 LYS A 361
THR A 365
ILE A 379
 None
 0.93A 4e0fB-4zxzA:
undetectable		 4e0fB-4zxzA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 5 THR A 116
THR A 133
THR A 365
HIS A 167
 None
 1.41A 4pgfB-4zxzA:
undetectable		 4pgfB-4zxzA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 7 ARG A 153
THR A 133
GLY A 114
THR A 116
 None
 0.98A 4qwpB-4zxzA:
undetectable		 4qwpB-4zxzA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 4 ASN A 332
VAL A 296
THR A 303
ILE A 302
 None
 0.99A 4retA-4zxzA:
undetectable		 4retA-4zxzA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 4 ASN A 332
VAL A 296
THR A 303
ILE A 302
 None
 0.99A 4retC-4zxzA:
undetectable		 4retC-4zxzA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		5 / 11 ILE A 190
THR A 217
GLY A 216
ASP A 212
GLU A 362
 None
 1.37A 4xt7A-4zxzA:
undetectable		 4xt7A-4zxzA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		3 / 3 ARG A 161
ASP A 156
TYR A 391
 None
 0.73A 4yo9B-4zxzA:
undetectable		 4yo9B-4zxzA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 8 SER A 397
THR A 148
THR A 150
ILE A 139
 None
 1.07A 5jhdE-4zxzA:
undetectable
5jhdG-4zxzA:
undetectable		 5jhdE-4zxzA:
19.38
5jhdG-4zxzA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 5 ILE A 110
LEU A  85
GLY A  86
PHE A  89
 None
 0.69A 5kmdC-4zxzA:
undetectable
5kmdD-4zxzA:
undetectable		 5kmdC-4zxzA:
17.92
5kmdD-4zxzA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 6 GLY A  86
GLU A  87
PHE A  89
ILE A 110
 None
 0.85A 5kmfA-4zxzA:
undetectable
5kmfC-4zxzA:
undetectable		 5kmfA-4zxzA:
17.92
5kmfC-4zxzA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 7 VAL A 422
LEU A  19
PHE A 366
PHE A  46
 None
 1.03A 6aycA-4zxzA:
undetectable		 6aycA-4zxzA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		3 / 3 TYR A 259
HIS A 257
PHE A 273
 None
 1.03A 6esmA-4zxzA:
undetectable		 6esmA-4zxzA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 4 ASP A 171
ILE A 356
PRO A 357
LEU A 351
 None
 0.92A 6mkeB-4zxzA:
undetectable		 6mkeB-4zxzA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4zxz LEVOGLUCOSAN KINASE
(Lipomyces
starkeyi) 		4 / 4 ASP A 171
ILE A 356
PRO A 357
LEU A 351
 None
 0.97A 6mkeA-4zxzA:
undetectable		 6mkeA-4zxzA:
10.02