SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zy7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A 117
THR A  43
LEU A  91
VAL A 107
THR A  85
 None
 0.91A 2jn3A-4zy7A:
undetectable		 2jn3A-4zy7A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817
(Mycolicibacteriu
m
smegmatis) 		5 / 7 ALA A  51
GLY A  53
SER A  55
ARG A 113
GLY A  71
 None
 1.04A 5e26A-4zy7A:
undetectable
5e26B-4zy7A:
undetectable		 5e26A-4zy7A:
16.48
5e26B-4zy7A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817
(Mycolicibacteriu
m
smegmatis) 		5 / 7 GLY A  53
SER A  55
ARG A 113
GLY A  71
ALA A  51
 None
 1.08A 5e26C-4zy7A:
undetectable
5e26D-4zy7A:
undetectable		 5e26C-4zy7A:
16.48
5e26D-4zy7A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817
(Mycolicibacteriu
m
smegmatis) 		4 / 8 ALA A  51
GLY A  53
ARG A 113
GLY A  71
 None
 0.90A 5e26C-4zy7A:
undetectable
5e26D-4zy7A:
undetectable		 5e26C-4zy7A:
16.48
5e26D-4zy7A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ALA A  94
THR A  95
VAL A 124
VAL A  19
 None
None
None
PEG  A 205 ( 4.2A)
 0.96A 5eckA-4zy7A:
undetectable		 5eckA-4zy7A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ALA A  94
THR A  95
VAL A 124
VAL A  19
 None
None
None
PEG  A 205 ( 4.2A)
 0.82A 5eclA-4zy7A:
undetectable		 5eclA-4zy7A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ALA A  94
THR A  95
VAL A 124
VAL A  19
 None
None
None
PEG  A 205 ( 4.2A)
 0.91A 5eclD-4zy7A:
undetectable		 5eclD-4zy7A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLY A  53
SER A  55
ARG A 113
GLY A  71
 None
 0.99A 5kprA-4zy7A:
undetectable		 5kprA-4zy7A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A 104
SER A 106
LEU A  92
LEU A  97
LEU A  93
 None
None
EDO  A 202 (-4.8A)
None
None
 1.23A 5nwwA-4zy7A:
undetectable		 5nwwA-4zy7A:
12.59