SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zy8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4zy8 PROTEIN LST4
(Kluyveromyces
lactis) 		5 / 12 PHE C  11
CYH C 100
LEU C 121
LEU C 167
LEU C  32
 None
 1.13A 1zgyA-4zy8C:
undetectable		 1zgyA-4zy8C:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4zy8 PROTEIN LST4
(Kluyveromyces
lactis) 		3 / 3 THR C 137
PRO C 141
TYR C 131
 None
 0.98A 2dxrA-4zy8C:
undetectable		 2dxrA-4zy8C:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 4zy8 PROTEIN LST4
(Kluyveromyces
lactis) 		4 / 8 GLN C  17
LEU C 129
LYS C 130
LEU C 140
 None
 1.10A 2xn3A-4zy8C:
undetectable
2xn3B-4zy8C:
undetectable		 2xn3A-4zy8C:
20.29
2xn3B-4zy8C:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4zy8 PROTEIN LST4
(Kluyveromyces
lactis) 		5 / 12 LEU C 132
ILE C  96
LEU C  13
VAL C 155
LEU C  47
 None
 0.94A 5ycnA-4zy8C:
undetectable		 5ycnA-4zy8C:
22.42