SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		5 / 11 ARG A 630
SER A 622
LEU A 621
ALA A 620
LEU A 643
 None
 1.39A 1hwkB-5a01A:
undetectable		 1hwkB-5a01A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		5 / 11 ARG A 630
SER A 622
LEU A 621
ALA A 620
LEU A 643
 None
 1.40A 1hwkA-5a01A:
undetectable		 1hwkA-5a01A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_2
(HMG-COA REDUCTASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		5 / 11 ARG A 630
SER A 622
LEU A 621
ALA A 620
LEU A 643
 None
 1.38A 1hwkD-5a01A:
undetectable		 1hwkD-5a01A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		5 / 11 ARG A 630
SER A 622
LEU A 621
ALA A 620
LEU A 643
 None
 1.39A 1hwkC-5a01A:
undetectable		 1hwkC-5a01A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 6 ASN A 454
PHE A 457
HIS A 461
ALA A 456
 None
 1.13A 1l7xA-5a01A:
12.0		 1l7xA-5a01A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ARG A 530
ASP A 459
ASN A 454
 None
 0.90A 1nbhA-5a01A:
3.4		 1nbhA-5a01A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ARG A 530
ASP A 459
ASN A 454
 None
 0.89A 1nbhD-5a01A:
3.1		 1nbhD-5a01A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ARG A 852
ILE A 921
TRP A 894
 None
 1.16A 1qomA-5a01A:
undetectable		 1qomA-5a01A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 6 THR A 850
GLN A 936
HIS A 742
ASN A 765
 None
 1.14A 1tt0A-5a01A:
2.2		 1tt0A-5a01A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 6 THR A 850
GLN A 936
HIS A 742
ASN A 765
 None
 1.14A 1tt0B-5a01A:
1.8		 1tt0B-5a01A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 6 THR A 850
GLN A 936
HIS A 742
ASN A 765
 None
 1.17A 1tt0C-5a01A:
undetectable		 1tt0C-5a01A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 6 THR A 850
GLN A 936
HIS A 742
ASN A 765
 None
 1.15A 1tt0D-5a01A:
undetectable		 1tt0D-5a01A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 6 SER A 428
SER A 533
GLN A 525
ASP A 459
 None
 1.39A 2cl5B-5a01A:
4.4		 2cl5B-5a01A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 LEU A 971
LEU A 946
MET A 872
 None
 0.80A 2itzA-5a01A:
undetectable		 2itzA-5a01A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 7 PHE A 922
LEU A 878
VAL A 910
THR A 909
 None
 0.96A 2qblA-5a01A:
undetectable		 2qblA-5a01A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ASN A 364
ARG A 367
ASP A 425
 None
 0.96A 2qe6A-5a01A:
undetectable		 2qe6A-5a01A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ASN A 364
ARG A 367
ASP A 425
 None
 0.93A 2qe6B-5a01A:
undetectable		 2qe6B-5a01A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 6 THR A 982
MET A 954
PHE A 732
ILE A 733
 None
None
12V  A2060 (-4.4A)
None
 1.40A 2w98B-5a01A:
3.9		 2w98B-5a01A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 6 SER A 428
SER A 533
GLN A 525
ASP A 459
 None
 1.40A 2zvjA-5a01A:
undetectable		 2zvjA-5a01A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ASN A 948
ASP A 874
GLN A 876
 None
 0.69A 3eeyC-5a01A:
5.2		 3eeyC-5a01A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ASN A 948
ASP A 874
GLN A 876
 None
 0.68A 3eeyD-5a01A:
3.7		 3eeyD-5a01A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ASN A 948
ASP A 874
GLN A 876
 None
 0.69A 3eeyE-5a01A:
5.2		 3eeyE-5a01A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		5 / 11 SER A 599
LEU A 643
ASP A 642
LEU A 589
SER A 590
 None
 1.28A 3ko0A-5a01A:
undetectable
3ko0B-5a01A:
undetectable
3ko0I-5a01A:
undetectable
3ko0J-5a01A:
undetectable		 3ko0A-5a01A:
9.45
3ko0B-5a01A:
9.45
3ko0I-5a01A:
9.45
3ko0J-5a01A:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 HIS A 537
HIS A 538
HIS A 535
 12V  A2060 (-4.1A)
None
None
 0.83A 3mihA-5a01A:
undetectable		 3mihA-5a01A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ARG A 852
ILE A 921
TRP A 894
 None
 1.16A 3nw2B-5a01A:
undetectable		 3nw2B-5a01A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 GLY A 431
THR A 433
ASN A 429
 None
 0.66A 3v4tD-5a01A:
2.2		 3v4tD-5a01A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		5 / 12 TYR A 588
TYR A1032
LEU A1039
ILE A 706
LEU A 691
 None
 1.36A 4k36B-5a01A:
undetectable		 4k36B-5a01A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		5 / 11 TYR A 588
TYR A1032
LEU A1039
ILE A 706
LEU A 691
 None
 1.36A 4k37A-5a01A:
2.6		 4k37A-5a01A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		5 / 12 ASN A 649
ARG A 675
ASN A 666
LEU A 664
GLN A 687
 None
 1.36A 4kuoA-5a01A:
undetectable		 4kuoA-5a01A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		5 / 12 SER A 697
GLY A 698
ALA A 557
ARG A 682
GLU A 722
 None
 0.89A 4xt8A-5a01A:
3.6		 4xt8A-5a01A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 7 HIS A 600
GLY A 594
ASN A 595
HIS A 596
 None
 1.04A 5a5zC-5a01A:
undetectable		 5a5zC-5a01A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 5 SER A 428
SER A 533
GLN A 525
ASP A 459
 None
 1.39A 5fhrB-5a01A:
3.6		 5fhrB-5a01A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		3 / 3 ASN A 432
TYR A 413
CYH A 446
 None
 0.89A 5lsuB-5a01A:
undetectable		 5lsuB-5a01A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 5a01 O-GLYCOSYLTRANSFERAS
E
(Drosophila
melanogaster) 		4 / 6 ILE A 586
TYR A 588
LEU A1036
VAL A 614
 None
 1.22A 6f6jA-5a01A:
undetectable		 6f6jA-5a01A:
undetectable