SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a05'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 7 GLY A 187
ILE A 327
TYR A 328
GLY A 181
 None
 0.84A 11gsB-5a05A:
undetectable		 11gsB-5a05A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		3 / 3 GLN A 136
TYR A 250
ARG A 251
 None
 0.74A 1gtbA-5a05A:
undetectable		 1gtbA-5a05A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 4 VAL A 205
ALA A 207
LEU A 183
PHE A 227
 None
 0.93A 1q97B-5a05A:
undetectable		 1q97B-5a05A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 7 THR A  47
TYR A  48
TYR A  52
LEU A  37
 None
 0.90A 1qzrA-5a05A:
undetectable		 1qzrA-5a05A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 7 THR A  47
TYR A  48
TYR A  52
LEU A  37
 None
 0.92A 1qzrB-5a05A:
undetectable		 1qzrB-5a05A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 4 LEU A 305
THR A 306
ILE A  76
HIS A  99
 None
 1.20A 2jfaB-5a05A:
undetectable		 2jfaB-5a05A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 8 ARG A 213
SER A  84
GLY A 181
MET A 184
 None
 1.07A 2qd3A-5a05A:
4.3		 2qd3A-5a05A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		3 / 3 TYR A 196
ASP A 320
HIS A 161
 None
 0.92A 3e23A-5a05A:
4.2		 3e23A-5a05A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 320
GLY A 162
HIS A 161
ASN A 192
THR A 265
 None
 0.98A 3eeyA-5a05A:
3.1		 3eeyA-5a05A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 320
GLY A 162
HIS A 161
ASN A 192
THR A 265
 None
 0.98A 3eeyB-5a05A:
3.1		 3eeyB-5a05A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 320
GLY A 162
HIS A 161
ASN A 192
THR A 265
 None
 0.99A 3eeyC-5a05A:
3.0		 3eeyC-5a05A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 320
GLY A 162
HIS A 161
ASN A 192
THR A 265
 None
 0.99A 3eeyD-5a05A:
3.0		 3eeyD-5a05A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 320
GLY A 162
HIS A 161
ASN A 192
THR A 265
 None
 0.98A 3eeyE-5a05A:
3.8		 3eeyE-5a05A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 320
GLY A 162
HIS A 161
ASN A 192
THR A 265
 None
 0.98A 3eeyF-5a05A:
4.6		 3eeyF-5a05A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 320
GLY A 162
HIS A 161
ASN A 192
THR A 265
 None
 0.99A 3eeyH-5a05A:
3.1		 3eeyH-5a05A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 320
GLY A 162
HIS A 161
ASN A 192
THR A 265
 None
 1.00A 3eeyI-5a05A:
4.3		 3eeyI-5a05A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 ASP A 320
GLY A 162
HIS A 161
ASN A 192
THR A 265
 None
 0.96A 3eeyJ-5a05A:
3.2		 3eeyJ-5a05A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 4 ARG A 217
ASP A 212
ASP A 215
PRO A 216
 None
 1.31A 3fgrB-5a05A:
undetectable		 3fgrB-5a05A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		3 / 3 SER A  39
GLY A  40
THR A  41
 NDP  A1340 (-2.5A)
NDP  A1340 (-3.5A)
NDP  A1340 (-3.6A)
 0.23A 3k9wA-5a05A:
2.5		 3k9wA-5a05A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		3 / 3 TYR A 189
ASP A 320
ASP A 315
 BGC  A1343 (-4.2A)
None
None
 0.86A 3ou6B-5a05A:
3.0		 3ou6B-5a05A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 5 LEU A 276
LEU A 151
GLY A 152
GLY A 254
 None
 0.84A 3si7C-5a05A:
undetectable
3si7D-5a05A:
undetectable		 3si7C-5a05A:
19.43
3si7D-5a05A:
19.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		7 / 7 LYS A 104
ARG A 132
PHE A 163
ARG A 172
ASP A 185
TYR A 189
TYR A 267
 BGC  A1343 (-2.6A)
NDP  A1340 (-3.7A)
GLC  A1341 ( 3.6A)
NDP  A1340 (-2.8A)
BGC  A1343 ( 3.1A)
BGC  A1343 (-4.2A)
BGC  A1343 (-4.4A)
 0.13A 5a06A-5a05A:
57.4		 5a06A-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		6 / 6 ARG A   5
ASP A  75
LYS A  98
HIS A  99
ARG A 125
ILE A 304
 None
 0.46A 5a06A-5a05A:
57.4		 5a06A-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_A_SORA1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 5 LYS A 290
ASP A 298
HIS A 299
GLU A 302
 None
 0.28A 5a06A-5a05A:
57.4		 5a06A-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		7 / 7 LYS A 104
ARG A 132
PHE A 163
ARG A 172
ASP A 185
ILE A 186
TYR A 189
 BGC  A1343 (-2.6A)
NDP  A1340 (-3.7A)
GLC  A1341 ( 3.6A)
NDP  A1340 (-2.8A)
BGC  A1343 ( 3.1A)
None
BGC  A1343 (-4.2A)
 0.11A 5a06B-5a05A:
33.4		 5a06B-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		6 / 7 ILE A 117
CYH A 120
LYS A 126
LEU A 127
GLY A 313
GLY A 314
 None
 0.23A 5a06B-5a05A:
33.4		 5a06B-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_B_SORB1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 5 ASP A  75
LYS A  98
HIS A  99
ARG A 125
ILE A 304
 None
 0.12A 5a06B-5a05A:
57.1		 5a06B-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		7 / 7 LYS A 104
ARG A 132
PHE A 163
ARG A 172
ASP A 185
TYR A 189
TYR A 267
 BGC  A1343 (-2.6A)
NDP  A1340 (-3.7A)
GLC  A1341 ( 3.6A)
NDP  A1340 (-2.8A)
BGC  A1343 ( 3.1A)
BGC  A1343 (-4.2A)
BGC  A1343 (-4.4A)
 0.14A 5a06C-5a05A:
57.1		 5a06C-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 6 CYH A 120
LYS A 126
GLY A 313
GLY A 314
ASP A 315
 None
 0.22A 5a06D-5a05A:
57.5		 5a06D-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 6 GLU A 309
GLY A 313
GLY A 314
ASP A 315
 None
 1.02A 5a06D-5a05A:
57.5		 5a06D-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		7 / 7 LYS A 104
ARG A 132
PHE A 163
ARG A 172
ASP A 185
TYR A 189
TYR A 267
 BGC  A1343 (-2.6A)
NDP  A1340 (-3.7A)
GLC  A1341 ( 3.6A)
NDP  A1340 (-2.8A)
BGC  A1343 ( 3.1A)
BGC  A1343 (-4.2A)
BGC  A1343 (-4.4A)
 0.11A 5a06D-5a05A:
57.5		 5a06D-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_D_SORD1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 5 ASP A  75
LYS A  98
HIS A  99
ARG A 125
ILE A 304
 None
 0.10A 5a06D-5a05A:
57.5		 5a06D-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		7 / 7 LYS A 104
ARG A 132
PHE A 163
ARG A 172
ASP A 185
TYR A 189
TYR A 267
 BGC  A1343 (-2.6A)
NDP  A1340 (-3.7A)
GLC  A1341 ( 3.6A)
NDP  A1340 (-2.8A)
BGC  A1343 ( 3.1A)
BGC  A1343 (-4.2A)
BGC  A1343 (-4.4A)
 0.09A 5a06E-5a05A:
57.5		 5a06E-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		7 / 7 LYS A 104
ARG A 132
PHE A 163
ARG A 172
ASP A 185
TYR A 189
TYR A 267
 BGC  A1343 (-2.6A)
NDP  A1340 (-3.7A)
GLC  A1341 ( 3.6A)
NDP  A1340 (-2.8A)
BGC  A1343 ( 3.1A)
BGC  A1343 (-4.2A)
BGC  A1343 (-4.4A)
 0.16A 5a06F-5a05A:
57.4		 5a06F-5a05A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A06_F_SORF1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 5 ASP A  75
LYS A  98
HIS A  99
ARG A 125
ILE A 304
 None
 0.08A 5a06F-5a05A:
57.4		 5a06F-5a05A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 8 ILE A 186
ARG A 172
GLY A 181
ASN A  83
 None
NDP  A1340 (-2.8A)
None
NDP  A1340 (-3.9A)
 0.89A 5hwaA-5a05A:
undetectable		 5hwaA-5a05A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 LEU A 127
GLY A 130
ALA A 107
VAL A  79
TYR A  78
 None
 1.26A 5kbwB-5a05A:
undetectable		 5kbwB-5a05A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		5 / 12 VAL A  74
ASP A  75
LEU A  37
ALA A  10
LEU A 297
 None
 1.29A 5nd4B-5a05A:
3.0		 5nd4B-5a05A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE
(Caulobacter
vibrioides) 		4 / 6 GLU A 260
ARG A 249
ARG A 273
ASP A 160
 None
 1.14A 5zw4A-5a05A:
5.7		 5zw4A-5a05A:
20.12