SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		3 / 3 LEU A 198
ARG A 187
ILE A 200
 None
 0.60A 2xn5B-5a0dA:
undetectable		 2xn5B-5a0dA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 5 GLU A 202
GLY A 199
TYR A 204
GLU A 242
 None
 1.40A 3w9tA-5a0dA:
undetectable		 3w9tA-5a0dA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 5 GLU A 202
GLY A 199
TYR A 204
GLU A 242
 None
 1.39A 3w9tC-5a0dA:
undetectable		 3w9tC-5a0dA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 5 GLU A 202
GLY A 199
TYR A 204
GLU A 242
 None
 1.39A 3w9tD-5a0dA:
undetectable		 3w9tD-5a0dA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 5 GLU A 202
GLY A 199
TYR A 204
GLU A 242
 None
 1.40A 3w9tG-5a0dA:
undetectable		 3w9tG-5a0dA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 7 LYS A 111
ARG A 212
TYR A 123
TYR A 193
 None
 1.33A 5a06A-5a0dA:
undetectable		 5a06A-5a0dA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 7 LYS A 111
ARG A 212
TYR A 123
TYR A 193
 None
 1.32A 5a06C-5a0dA:
undetectable		 5a06C-5a0dA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 7 LYS A 111
ARG A 212
TYR A 123
TYR A 193
 None
 1.34A 5a06D-5a0dA:
undetectable		 5a06D-5a0dA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 7 LYS A 111
ARG A 212
TYR A 123
TYR A 193
 None
 1.33A 5a06E-5a0dA:
undetectable		 5a06E-5a0dA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 7 LYS A 111
ARG A 212
TYR A 123
TYR A 193
 None
 1.37A 5a06F-5a0dA:
undetectable		 5a06F-5a0dA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 4 LEU A 256
GLY A 162
SER A 163
SER A 164
 None
 1.30A 5uunA-5a0dA:
undetectable		 5uunA-5a0dA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5a0d SURFACE ANCHORED
PROTEIN
(Clostridium
perfringens) 		4 / 4 LEU A 256
GLY A 162
SER A 163
SER A 164
 None
 1.33A 5uunB-5a0dA:
undetectable		 5uunB-5a0dA:
20.20