SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a0l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5a0l FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
pyogenes) 		3 / 3 ASP A 132
PHE A 253
VAL A 269
 None
 0.76A 1kijB-5a0lA:
undetectable		 1kijB-5a0lA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 5a0l FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
pyogenes) 		4 / 5 LEU A 250
SER A 169
LEU A 231
LEU A 160
 None
 0.86A 1yajD-5a0lA:
undetectable		 1yajD-5a0lA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 5a0l FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
pyogenes) 		5 / 12 GLY A 166
ILE A 178
GLY A 177
ASN A 172
LEU A 231
 None
 1.12A 3eeyE-5a0lA:
undetectable		 3eeyE-5a0lA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 5a0l FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
pyogenes) 		5 / 12 GLY A 166
ILE A 178
GLY A 177
ASN A 172
LEU A 231
 None
 1.06A 3eeyF-5a0lA:
undetectable		 3eeyF-5a0lA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 5a0l FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
pyogenes) 		5 / 12 GLY A 166
ILE A 178
GLY A 177
ASN A 172
LEU A 231
 None
 1.18A 3eeyI-5a0lA:
undetectable		 3eeyI-5a0lA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 5a0l FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
pyogenes) 		5 / 12 GLY A 166
ILE A 178
GLY A 177
ASN A 172
LEU A 231
 None
 1.06A 3eeyJ-5a0lA:
undetectable		 3eeyJ-5a0lA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5a0l FIBRONECTIN-BINDING
PROTEIN
(Streptococcus
pyogenes) 		4 / 5 PHE A 110
LEU A 155
GLY A 135
ILE A 252
 None
 0.78A 3wrkA-5a0lA:
undetectable		 3wrkA-5a0lA:
17.30