SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		5 / 12 VAL A 142
PHE A  91
HIS A 139
ILE A 166
PHE A 103
 None
 1.07A 1c9hA-5a11A:
undetectable		 1c9hA-5a11A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 6 TRP A 234
GLY A 188
PHE A 189
SER A 132
 None
None
None
IOD  A1350 ( 4.3A)
 1.40A 2a3cB-5a11A:
undetectable		 2a3cB-5a11A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 7 GLY A 185
SER A 249
PHE A 202
ARG A 157
 IOD  A1349 ( 3.8A)
None
None
IOD  A1349 (-4.5A)
 1.03A 2c8aD-5a11A:
undetectable		 2c8aD-5a11A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 7 PHE A 251
SER A 312
PHE A 199
GLY A 185
 None
None
None
IOD  A1349 ( 3.8A)
 0.97A 2v0mC-5a11A:
undetectable		 2v0mC-5a11A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 5 ALA A  21
GLY A  39
CYH A  37
HIS A 326
 None
 1.49A 2yldA-5a11A:
undetectable		 2yldA-5a11A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 5 ALA A  21
GLY A  39
CYH A  37
HIS A 326
 None
 1.49A 2ylgA-5a11A:
undetectable		 2ylgA-5a11A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 5 ALA A  21
GLY A  39
CYH A  37
HIS A 326
 None
 1.49A 3zwiA-5a11A:
undetectable		 3zwiA-5a11A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 6 GLY A 308
ARG A  80
GLU A  41
ARG A 335
 None
 1.17A 4bqfA-5a11A:
undetectable		 4bqfA-5a11A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 4 ALA A  21
GLY A  39
CYH A  37
HIS A 326
 None
 1.49A 4cipA-5a11A:
undetectable		 4cipA-5a11A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		3 / 3 TYR A 219
ARG A 223
SER A 221
 None
 0.73A 4khpI-5a11A:
undetectable
4khpJ-5a11A:
undetectable		 4khpI-5a11A:
15.69
4khpJ-5a11A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 6 ARG A 157
GLU A 220
GLU A 266
SER A 249
 IOD  A1349 (-4.5A)
None
None
None
 1.31A 4kr3A-5a11A:
undetectable		 4kr3A-5a11A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 4 ILE A  64
SER A  63
ASP A  49
ASP A  42
 None
 1.38A 4krhB-5a11A:
undetectable		 4krhB-5a11A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 5 ASP A  56
PHE A  57
PHE A  55
VAL A  12
 None
None
None
IOD  A1351 ( 4.0A)
 1.16A 5a1rA-5a11A:
undetectable		 5a1rA-5a11A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		5 / 12 VAL A 142
PHE A  91
HIS A 139
ILE A 166
PHE A 103
 None
 1.01A 5hkgA-5a11A:
undetectable		 5hkgA-5a11A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		5 / 11 ILE A 262
PHE A 251
THR A 239
VAL A 224
VAL A 198
 None
 1.43A 5jkwA-5a11A:
undetectable		 5jkwA-5a11A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 5 ALA A  21
GLY A  39
CYH A  37
HIS A 326
 None
 1.47A 5jliA-5a11A:
undetectable		 5jliA-5a11A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 4 ALA A  21
GLY A  39
CYH A  37
HIS A 326
 None
 1.49A 5jslA-5a11A:
undetectable		 5jslA-5a11A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		4 / 5 ALA A  21
GLY A  39
CYH A  37
HIS A 326
 None
 1.49A 5jt4A-5a11A:
undetectable		 5jt4A-5a11A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 5a11 THIOCYANATE FORMING
PROTEIN
(Thlaspi
arvense) 		3 / 3 ARG A  94
PRO A 155
TYR A  45
 None
 1.03A 5tzoB-5a11A:
undetectable		 5tzoB-5a11A:
22.99