SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 5a15 BTB/POZ
DOMAIN-CONTAINING
PROTEIN KCTD16
(Homo
sapiens) 		4 / 7 LEU A  29
PHE A  55
ILE A  75
PHE A 113
 None
 0.80A 2opxA-5a15A:
undetectable		 2opxA-5a15A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 5a15 BTB/POZ
DOMAIN-CONTAINING
PROTEIN KCTD16
(Homo
sapiens) 		5 / 12 PHE A  55
THR A  38
ARG A  72
TYR A  36
LEU A  89
 None
 1.38A 2rctA-5a15A:
undetectable		 2rctA-5a15A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5a15 BTB/POZ
DOMAIN-CONTAINING
PROTEIN KCTD16
(Homo
sapiens) 		3 / 3 TYR A  88
GLU A 109
TYR A 112
 None
 0.91A 3ug8A-5a15A:
undetectable		 3ug8A-5a15A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5a15 BTB/POZ
DOMAIN-CONTAINING
PROTEIN KCTD16
(Homo
sapiens) 		3 / 3 GLU A 109
ALA A 110
PHE A 113
 None
 0.33A 4v1fA-5a15A:
undetectable		 4v1fA-5a15A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5a15 BTB/POZ
DOMAIN-CONTAINING
PROTEIN KCTD16
(Homo
sapiens) 		3 / 3 GLU A 109
ALA A 110
PHE A 113
 None
 0.37A 4v1fC-5a15A:
undetectable		 4v1fC-5a15A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5a15 BTB/POZ
DOMAIN-CONTAINING
PROTEIN KCTD16
(Homo
sapiens) 		4 / 7 LYS A 103
LEU A 106
LEU A 122
LEU A 118
 None
 0.69A 4wg0B-5a15A:
undetectable
4wg0C-5a15A:
undetectable		 4wg0B-5a15A:
8.33
4wg0C-5a15A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5a15 BTB/POZ
DOMAIN-CONTAINING
PROTEIN KCTD16
(Homo
sapiens) 		4 / 7 LEU A 122
LEU A 118
LYS A 103
LEU A 106
 None
 0.72A 4wg0L-5a15A:
undetectable
4wg0M-5a15A:
undetectable		 4wg0L-5a15A:
8.33
4wg0M-5a15A:
8.33