SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a1h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB8_0 (GRAMICIDIN A)	5a1h	SPINDLIN-3 (Homo sapiens)	4 / 5	VAL A 50 GLY A 51 VAL A 72 TRP A 161	None	1.17A	1tkqB-5a1hA: undetectable	1tkqB-5a1hA: 3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MB5_A_NMYA301_0 (AAC(3)-IIIB PROTEIN)	5a1h	SPINDLIN-3 (Homo sapiens)	5 / 11	TYR A 175 ASP A 91 TYR A 166 ASP A 183 HIS A 135	None	1.34A	6mb5A-5a1hA: undetectable	6mb5A-5a1hA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MB9_A_NMYA303_0 (AAC(3)-IIIB PROTEIN)	5a1h	SPINDLIN-3 (Homo sapiens)	5 / 10	TYR A 175 ASP A 91 TYR A 166 ASP A 183 HIS A 135	None	1.38A	6mb9A-5a1hA: undetectable	6mb9A-5a1hA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MB9_B_NMYB302_0 (AAC(3)-IIIB PROTEIN)	5a1h	SPINDLIN-3 (Homo sapiens)	5 / 10	TYR A 175 ASP A 91 TYR A 166 ASP A 183 HIS A 135	None	1.36A	6mb9B-5a1hA: undetectable	6mb9B-5a1hA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MB9_C_NMYC302_0 (AAC(3)-IIIB PROTEIN)	5a1h	SPINDLIN-3 (Homo sapiens)	5 / 10	TYR A 175 ASP A 91 TYR A 166 ASP A 183 HIS A 135	None	1.38A	6mb9C-5a1hA: undetectable	6mb9C-5a1hA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MB9_D_NMYD302_0 (AAC(3)-IIIB PROTEIN)	5a1h	SPINDLIN-3 (Homo sapiens)	5 / 10	TYR A 175 ASP A 91 TYR A 166 ASP A 183 HIS A 135	None	1.38A	6mb9D-5a1hA: undetectable	6mb9D-5a1hA: 17.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TKQ_B_DVAB8_0","GRAMICIDIN A","5a1h","SPINDLIN-3","Homo sapiens",4,"VAL A  50;GLY A  51;VAL A  72;TRP A 161","None","1.17A","1tkqB-5a1hA:undetectable","1tkqB-5a1hA:3.24"],["6MB5_A_NMYA301_0","AAC(3)-IIIB PROTEIN","5a1h","SPINDLIN-3","Homo sapiens",5,"TYR A 175;ASP A  91;TYR A 166;ASP A 183;HIS A 135","None","1.34A","6mb5A-5a1hA:undetectable","6mb5A-5a1hA:17.05"],["6MB9_A_NMYA303_0","AAC(3)-IIIB PROTEIN","5a1h","SPINDLIN-3","Homo sapiens",5,"TYR A 175;ASP A  91;TYR A 166;ASP A 183;HIS A 135","None","1.38A","6mb9A-5a1hA:undetectable","6mb9A-5a1hA:17.05"],["6MB9_B_NMYB302_0","AAC(3)-IIIB PROTEIN","5a1h","SPINDLIN-3","Homo sapiens",5,"TYR A 175;ASP A  91;TYR A 166;ASP A 183;HIS A 135","None","1.36A","6mb9B-5a1hA:undetectable","6mb9B-5a1hA:17.05"],["6MB9_C_NMYC302_0","AAC(3)-IIIB PROTEIN","5a1h","SPINDLIN-3","Homo sapiens",5,"TYR A 175;ASP A  91;TYR A 166;ASP A 183;HIS A 135","None","1.38A","6mb9C-5a1hA:undetectable","6mb9C-5a1hA:17.05"],["6MB9_D_NMYD302_0","AAC(3)-IIIB PROTEIN","5a1h","SPINDLIN-3","Homo sapiens",5,"TYR A 175;ASP A  91;TYR A 166;ASP A 183;HIS A 135","None","1.38A","6mb9D-5a1hA:undetectable","6mb9D-5a1hA:17.05"]]