SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5a1m ADSEVERIN
(Homo
sapiens) 		4 / 5 LEU A 317
GLN A 292
THR A 326
THR A 312
 None
 1.36A 2zj0C-5a1mA:
undetectable		 2zj0C-5a1mA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5a1m ADSEVERIN
(Homo
sapiens) 		4 / 5 LEU A 317
GLN A 292
THR A 326
THR A 312
 None
 1.36A 3ce6B-5a1mA:
undetectable		 3ce6B-5a1mA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5a1m ADSEVERIN
(Homo
sapiens) 		3 / 3 GLU A 281
GLU A 280
TRP A 296
 CA  A1351 (-3.0A)
None
None
 1.34A 3hrdA-5a1mA:
undetectable
3hrdE-5a1mA:
undetectable
3hrdF-5a1mA:
undetectable		 3hrdA-5a1mA:
12.50
3hrdE-5a1mA:
12.50
3hrdF-5a1mA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 5a1m ADSEVERIN
(Homo
sapiens) 		4 / 7 PHE A 283
GLY A 298
PHE A 272
PHE A 344
 None
 0.96A 3ko0D-5a1mA:
undetectable
3ko0E-5a1mA:
undetectable		 3ko0D-5a1mA:
22.41
3ko0E-5a1mA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 5a1m ADSEVERIN
(Homo
sapiens) 		4 / 7 PHE A 283
GLY A 298
PHE A 272
PHE A 344
 None
 0.87A 3ko0M-5a1mA:
undetectable
3ko0P-5a1mA:
undetectable		 3ko0M-5a1mA:
22.41
3ko0P-5a1mA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 5a1m ADSEVERIN
(Homo
sapiens) 		4 / 8 PHE A 283
GLY A 298
PHE A 272
PHE A 344
 None
 0.98A 3ko0O-5a1mA:
undetectable
3ko0Q-5a1mA:
undetectable		 3ko0O-5a1mA:
22.41
3ko0Q-5a1mA:
22.41