SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		4 / 7 TYR H 104
GLN H  16
THR H  22
GLN H  32
 None
 1.20A 1eiiA-5a20H:
undetectable		 1eiiA-5a20H:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		4 / 8 ASP H 105
SER H 154
THR H  22
ASP H  95
 None
 1.04A 1p7lC-5a20H:
undetectable		 1p7lC-5a20H:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		4 / 8 ASP H 105
SER H 154
THR H  22
ASP H  95
 None
 1.04A 1p7lD-5a20H:
undetectable		 1p7lD-5a20H:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		4 / 8 ASP H 105
SER H 154
THR H  22
ASP H  95
 None
 1.06A 1rg9A-5a20H:
undetectable		 1rg9A-5a20H:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		4 / 8 ASP H 105
SER H 154
THR H  22
ASP H  95
 None
 1.08A 1rg9B-5a20H:
undetectable		 1rg9B-5a20H:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		4 / 8 ASP H 105
SER H 154
THR H  22
ASP H  95
 None
 1.04A 1rg9C-5a20H:
undetectable		 1rg9C-5a20H:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		4 / 8 ASP H 105
SER H 154
THR H  22
ASP H  95
 None
 1.03A 1rg9D-5a20H:
undetectable		 1rg9D-5a20H:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		5 / 11 ILE H 128
GLY H  35
ASP H  95
GLY H 109
PHE H  15
 None
 0.99A 2fxdA-5a20H:
undetectable		 2fxdA-5a20H:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		3 / 3 PRO H 147
LEU H  43
SER H  58
 None
 0.44A 5fsaB-5a20H:
undetectable		 5fsaB-5a20H:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		4 / 8 ASP H 105
SER H 154
THR H  22
ASP H  95
 None
 1.13A 5t8sB-5a20H:
undetectable		 5t8sB-5a20H:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 5a20 MAJOR TAIL PROTEIN
GP17.1
(Bacillus
phage
SPP1) 		4 / 7 GLY H 109
PHE H 108
VAL H  94
SER H  17
 None
 1.07A 6hu9S-5a20H:
undetectable
6hu9q-5a20H:
undetectable		 6hu9S-5a20H:
19.75
6hu9q-5a20H:
21.62