SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 5a24 DIONAIN-1
(Dionaea
muscipula) 		3 / 3 TRP A   8
ALA A  34
VAL A 170
 None
 0.95A 1c4dA-5a24A:
undetectable
1c4dB-5a24A:
undetectable		 1c4dA-5a24A:
4.95
1c4dB-5a24A:
4.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1STF_E_CCSE25_0
(PAPAIN
STEFIN B (CYSTATIN
B))		 5a24 DIONAIN-1
(Dionaea
muscipula) 		7 / 10 GLN A  20
GLY A  24
TRP A  27
PHE A  29
SER A  30
HIS A 165
ALA A 166
 E64  A1224 (-3.2A)
E64  A1224 (-3.1A)
E64  A1224 (-4.9A)
None
None
E64  A1224 (-3.8A)
E64  A1224 ( 4.0A)
 0.28A 1stfE-5a24A:
36.2
1stfI-5a24A:
undetectable		 1stfE-5a24A:
45.95
1stfI-5a24A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5a24 DIONAIN-1
(Dionaea
muscipula) 		5 / 12 PRO A  99
ILE A  84
VAL A  78
TYR A  77
VAL A  32
 None
 1.18A 1z9hD-5a24A:
undetectable		 1z9hD-5a24A:
20.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AI8_A_HNQA255_1
(CATHEPSIN B)		 5a24 DIONAIN-1
(Dionaea
muscipula) 		4 / 7 GLN A  20
GLY A  24
HIS A 165
TRP A 189
 E64  A1224 (-3.2A)
E64  A1224 (-3.1A)
E64  A1224 (-3.8A)
None
 0.50A 3ai8A-5a24A:
27.6		 3ai8A-5a24A:
30.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 5a24 DIONAIN-1
(Dionaea
muscipula) 		4 / 5 PRO A 109
SER A 105
LEU A  49
SER A  50
 None
 1.21A 3iluH-5a24A:
undetectable		 3iluH-5a24A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 5a24 DIONAIN-1
(Dionaea
muscipula) 		5 / 11 LYS A 186
ALA A  13
GLN A 134
PRO A  71
PHE A  75
 None
 1.38A 4j4vA-5a24A:
undetectable		 4j4vA-5a24A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 5a24 DIONAIN-1
(Dionaea
muscipula) 		4 / 7 GLY A 171
MET A 201
ALA A 131
ILE A 136
 None
 0.94A 4txnA-5a24A:
undetectable		 4txnA-5a24A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 5a24 DIONAIN-1
(Dionaea
muscipula) 		4 / 7 GLY A 171
MET A 201
ALA A 131
ILE A 136
 None
 0.95A 4txnD-5a24A:
undetectable		 4txnD-5a24A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5a24 DIONAIN-1
(Dionaea
muscipula) 		5 / 10 VAL A  55
GLY A  65
GLY A  68
TRP A  27
ALA A  94
 None
None
E64  A1224 (-3.4A)
E64  A1224 (-4.9A)
None
 1.03A 5vm8B-5a24A:
undetectable		 5vm8B-5a24A:
19.92