SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 6 PRO A 518
ASP A 514
ASN A  82
TYR A  35
 None
EDO  A1572 ( 4.7A)
None
None
 1.31A 1hpkA-5a29A:
undetectable		 1hpkA-5a29A:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.17A 1kifA-5a29A:
undetectable		 1kifA-5a29A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.17A 1kifB-5a29A:
undetectable		 1kifB-5a29A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.17A 1kifC-5a29A:
undetectable		 1kifC-5a29A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.17A 1kifD-5a29A:
undetectable		 1kifD-5a29A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.17A 1kifE-5a29A:
undetectable		 1kifE-5a29A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.17A 1kifF-5a29A:
undetectable		 1kifF-5a29A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.17A 1kifG-5a29A:
undetectable		 1kifG-5a29A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.16A 1kifH-5a29A:
undetectable		 1kifH-5a29A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		3 / 3 ALA A 179
VAL A 181
TRP A 184
 None
 0.84A 1kqeA-5a29A:
undetectable
1kqeE-5a29A:
undetectable		 1kqeA-5a29A:
2.75
1kqeE-5a29A:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		3 / 3 ALA A 179
VAL A 181
TRP A 184
 None
 0.85A 1kqeB-5a29A:
undetectable
1kqeD-5a29A:
undetectable		 1kqeB-5a29A:
2.75
1kqeD-5a29A:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		3 / 3 TRP A 184
ALA A 179
VAL A 181
 None
 0.84A 1kqeB-5a29A:
undetectable
1kqeD-5a29A:
undetectable		 1kqeB-5a29A:
2.75
1kqeD-5a29A:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		3 / 3 TRP A 184
ALA A 179
VAL A 181
 None
 0.85A 1kqeA-5a29A:
undetectable
1kqeE-5a29A:
undetectable		 1kqeA-5a29A:
2.75
1kqeE-5a29A:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.21A 1ve9A-5a29A:
undetectable		 1ve9A-5a29A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		3 / 3 THR A 282
PRO A 284
PRO A 222
 None
 0.89A 2d55C-5a29A:
undetectable		 2d55C-5a29A:
1.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 GLY A 543
PHE A 124
GLY A 127
GLY A 128
PHE A 117
 None
 1.16A 2dpmA-5a29A:
undetectable		 2dpmA-5a29A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 TYR A 367
TYR A 363
ILE A 416
GLY A 372
 EDO  A1579 (-4.9A)
None
None
None
 1.12A 2du8G-5a29A:
undetectable		 2du8G-5a29A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 ALA A 485
LEU A 482
LEU A 524
LEU A 521
ILE A 516
 None
 1.11A 2jfaA-5a29A:
undetectable		 2jfaA-5a29A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 ALA A 485
LEU A 482
LEU A 524
LEU A 521
ILE A 516
 None
 1.01A 2qxsA-5a29A:
undetectable		 2qxsA-5a29A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 ALA A 485
LEU A 482
LEU A 524
LEU A 521
ILE A 516
 None
 1.00A 2qxsB-5a29A:
undetectable		 2qxsB-5a29A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 8 SER A 512
PRO A 463
LEU A 466
THR A  59
 None
 1.21A 2v0zO-5a29A:
undetectable		 2v0zO-5a29A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 8 TYR A 363
LEU A 360
ALA A 419
MET A 435
 None
 1.06A 2wekA-5a29A:
undetectable		 2wekA-5a29A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		3 / 3 ARG A  88
VAL A 164
THR A 110
 EDO  A1572 (-2.7A)
None
None
 0.72A 3cyxA-5a29A:
undetectable		 3cyxA-5a29A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 LEU A 428
ALA A 366
VAL A 332
ALA A 336
LEU A 340
 None
None
None
SRT  A1568 (-4.3A)
EDO  A1577 (-4.5A)
 1.08A 3ln1A-5a29A:
undetectable		 3ln1A-5a29A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 LEU A 428
ALA A 366
VAL A 332
ALA A 336
LEU A 340
 None
None
None
SRT  A1568 (-4.3A)
EDO  A1577 (-4.5A)
 1.09A 3ln1D-5a29A:
undetectable		 3ln1D-5a29A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		3 / 3 ASP A 328
GLU A 411
SER A 383
 None
 0.79A 3p2kA-5a29A:
undetectable		 3p2kA-5a29A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 8 GLY A 254
SER A 255
ILE A 173
ASP A 201
 EDO  A1578 (-3.5A)
None
None
None
 0.73A 3pwwA-5a29A:
undetectable		 3pwwA-5a29A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 8 THR A 465
ARG A 496
GLU A 410
THR A 409
 None
 0.93A 3rglA-5a29A:
undetectable		 3rglA-5a29A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 LEU A 360
LEU A 431
ASN A 434
MET A 435
ALA A 366
 None
EDO  A1579 ( 4.3A)
None
None
None
 1.15A 3ut5D-5a29A:
undetectable		 3ut5D-5a29A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 ASP A 514
SER A 542
GLY A 543
ASP A  55
 EDO  A1572 ( 4.7A)
None
None
None
 1.29A 3w9tB-5a29A:
undetectable		 3w9tB-5a29A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 ASP A 514
SER A 542
GLY A 543
ASP A  55
 EDO  A1572 ( 4.7A)
None
None
None
 1.29A 3w9tC-5a29A:
undetectable		 3w9tC-5a29A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 5 ASP A 514
SER A 542
GLY A 543
ASP A  55
 EDO  A1572 ( 4.7A)
None
None
None
 1.28A 3w9tD-5a29A:
undetectable		 3w9tD-5a29A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 6 TYR A 157
ASP A 514
GLU A 517
LEU A  90
 EDO  A1574 ( 4.9A)
EDO  A1572 ( 4.7A)
None
None
 1.01A 4ax8A-5a29A:
undetectable		 4ax8A-5a29A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 6 ARG A  28
ALA A 485
ASP A 490
LEU A 482
 None
 1.14A 4ot2A-5a29A:
3.0		 4ot2A-5a29A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 LEU A 360
LEU A 431
ASN A 434
MET A 435
ALA A 366
 None
EDO  A1579 ( 4.3A)
None
None
None
 1.10A 4x1iD-5a29A:
undetectable		 4x1iD-5a29A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 6 TYR A 481
GLY A 442
SER A 443
LEU A 444
 None
None
EDO  A1580 (-4.3A)
None
 1.24A 5bphA-5a29A:
undetectable		 5bphA-5a29A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 7 TYR A 481
GLY A 442
SER A 443
LEU A 444
 None
None
EDO  A1580 (-4.3A)
None
 1.21A 5bphB-5a29A:
undetectable		 5bphB-5a29A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 4 TYR A 481
GLY A 442
SER A 443
LEU A 444
 None
None
EDO  A1580 (-4.3A)
None
 1.26A 5bphC-5a29A:
undetectable		 5bphC-5a29A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 6 TYR A 481
GLY A 442
SER A 443
LEU A 444
 None
None
EDO  A1580 (-4.3A)
None
 1.23A 5bphD-5a29A:
undetectable		 5bphD-5a29A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 8 HIS A 149
GLY A 128
GLY A 127
VAL A 148
 None
 0.75A 5f8yA-5a29A:
undetectable		 5f8yA-5a29A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 8 HIS A 149
GLY A 128
GLY A 127
VAL A 148
 None
 0.77A 5f8yB-5a29A:
undetectable		 5f8yB-5a29A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 8 LEU A 414
LEU A 466
THR A 527
GLN A 477
 None
 1.10A 5hbsA-5a29A:
undetectable		 5hbsA-5a29A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 7 ILE A  57
VAL A  39
ARG A  44
GLN A  83
 None
 1.30A 5kkzC-5a29A:
undetectable
5kkzE-5a29A:
undetectable		 5kkzC-5a29A:
13.89
5kkzE-5a29A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 7 ILE A  57
VAL A  39
ARG A  44
GLN A  83
 None
 1.29A 5kkzM-5a29A:
undetectable
5kkzO-5a29A:
undetectable		 5kkzM-5a29A:
13.89
5kkzO-5a29A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 PHE A 549
ASN A 510
ALA A  54
VAL A  65
ILE A  77
 None
 1.35A 5mlmA-5a29A:
undetectable		 5mlmA-5a29A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 GLY A 193
HIS A 192
TYR A 125
ILE A 118
ALA A 119
 None
MN  A 601 ( 3.3A)
None
None
None
 0.87A 5n0sA-5a29A:
undetectable		 5n0sA-5a29A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 GLY A 193
HIS A 192
TYR A 125
ILE A 118
ALA A 119
 None
MN  A 601 ( 3.3A)
None
None
None
 0.93A 5n0wB-5a29A:
undetectable		 5n0wB-5a29A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 GLY A 193
HIS A 192
TYR A 125
ILE A 118
ALA A 119
 None
MN  A 601 ( 3.3A)
None
None
None
 0.92A 5n0xA-5a29A:
undetectable		 5n0xA-5a29A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 GLY A 193
HIS A 192
TYR A 125
ILE A 118
ALA A 119
 None
MN  A 601 ( 3.3A)
None
None
None
 0.90A 5n4iA-5a29A:
undetectable		 5n4iA-5a29A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		5 / 12 LEU A 360
LEU A 431
ASN A 434
MET A 435
ALA A 366
 None
EDO  A1579 ( 4.3A)
None
None
None
 1.16A 5nm5B-5a29A:
undetectable		 5nm5B-5a29A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 4 HIS A 192
HIS A 129
TYR A 544
GLU A 150
 MN  A 601 ( 3.3A)
MN  A 601 (-3.3A)
None
MN  A 601 (-2.4A)
 1.38A 5pahA-5a29A:
undetectable		 5pahA-5a29A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 5a29 EXOPOLYGALACTURONATE
LYASE
(Vibrio
vulnificus) 		4 / 6 TYR A 102
VAL A  29
VAL A  96
THR A  97
 None
 1.38A 6f32B-5a29A:
undetectable		 6f32B-5a29A:
21.92