SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a2a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		9 / 12 HIS A  98
TYR A 100
LEU A 177
LEU A 180
ASP A 213
HIS A 309
ASP A 310
ASP A 358
ARG A 362
 ACT  A1478 ( 4.1A)
ACT  A1479 (-3.9A)
None
None
ACT  A1479 (-2.6A)
None
ACT  A1479 ( 4.9A)
ACT  A1478 (-2.7A)
ACT  A1478 (-2.9A)
 0.68A 1dedA-5a2aA:
44.2		 1dedA-5a2aA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		7 / 12 HIS A  98
TYR A 100
LEU A 180
GLU A 242
ASP A 310
ASP A 358
ARG A 362
 ACT  A1478 ( 4.1A)
ACT  A1479 (-3.9A)
None
ACT  A1479 ( 4.5A)
ACT  A1479 ( 4.9A)
ACT  A1478 (-2.7A)
ACT  A1478 (-2.9A)
 0.96A 1dedA-5a2aA:
44.2		 1dedA-5a2aA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		9 / 12 HIS A  98
TYR A 100
LEU A 180
ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
ARG A 362
 ACT  A1478 ( 4.1A)
ACT  A1479 (-3.9A)
None
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
ACT  A1478 (-2.9A)
 0.65A 1dedB-5a2aA:
42.3		 1dedB-5a2aA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 7 TRP A  29
LEU A 240
LEU A 134
GLY A 209
 None
 0.90A 1gtiB-5a2aA:
undetectable		 1gtiB-5a2aA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		8 / 12 TYR A 100
ARG A 211
ASP A 213
LYS A 216
GLU A 242
TRP A 244
HIS A 309
ASP A 310
 ACT  A1479 (-3.9A)
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
None
ACT  A1479 ( 4.5A)
None
None
ACT  A1479 ( 4.9A)
 0.71A 1mxdA-5a2aA:
32.4		 1mxdA-5a2aA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		8 / 12 TYR A 100
HIS A 140
ARG A 211
ASP A 213
LYS A 216
GLU A 242
HIS A 309
ASP A 310
 ACT  A1479 (-3.9A)
ACT  A1479 (-4.4A)
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
None
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
 0.41A 1mxdA-5a2aA:
32.4		 1mxdA-5a2aA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		5 / 11 PHE A  90
PHE A 105
LEU A 239
PHE A 226
VAL A 230
 None
 1.13A 1q23J-5a2aA:
undetectable		 1q23J-5a2aA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 LYS A 234
ASP A 116
ASP A 206
 None
 0.91A 2br4D-5a2aA:
undetectable		 2br4D-5a2aA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		5 / 11 GLY A 113
TYR A  61
PHE A 112
VAL A  53
GLU A 103
 None
None
None
None
CA  A1482 ( 4.9A)
 1.32A 2fl5A-5a2aA:
undetectable
2fl5B-5a2aA:
undetectable
2fl5F-5a2aA:
undetectable		 2fl5A-5a2aA:
17.36
2fl5B-5a2aA:
17.59
2fl5F-5a2aA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 7 TYR A 286
TYR A 300
TYR A 335
ILE A 418
 None
 1.27A 2ph9A-5a2aA:
undetectable
2ph9B-5a2aA:
undetectable		 2ph9A-5a2aA:
18.93
2ph9B-5a2aA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 7 THR A  87
PRO A  88
GLY A  99
PHE A  36
 None
 0.99A 2vl2B-5a2aA:
undetectable		 2vl2B-5a2aA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		6 / 12 LEU A 177
ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
 None
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
 0.64A 3aicA-5a2aA:
9.7		 3aicA-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 LEU A 180
TRP A 244
TYR A 100
 None
None
ACT  A1479 (-3.9A)
 0.86A 3aicA-5a2aA:
9.8		 3aicA-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		6 / 12 LEU A 177
ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
 None
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
 0.64A 3aicB-5a2aA:
9.7		 3aicB-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 LEU A 180
TRP A 244
TYR A 100
 None
None
ACT  A1479 (-3.9A)
 0.90A 3aicB-5a2aA:
9.7		 3aicB-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		6 / 12 ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
TYR A 100
 ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
ACT  A1479 (-3.9A)
 0.67A 3aicC-5a2aA:
8.0		 3aicC-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		6 / 12 LEU A 177
ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
 None
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
 0.73A 3aicD-5a2aA:
9.9		 3aicD-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		6 / 12 LEU A 177
ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
 None
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
 0.70A 3aicE-5a2aA:
9.9		 3aicE-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 LEU A 180
TRP A 244
TYR A 100
 None
None
ACT  A1479 (-3.9A)
 0.89A 3aicE-5a2aA:
9.9		 3aicE-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		6 / 12 LEU A 177
ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
 None
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
 0.64A 3aicF-5a2aA:
9.7		 3aicF-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 LEU A 180
TRP A 244
TYR A 100
 None
None
ACT  A1479 (-3.9A)
 0.87A 3aicF-5a2aA:
9.8		 3aicF-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		6 / 12 LEU A 177
ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
 None
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
 0.63A 3aicG-5a2aA:
9.8		 3aicG-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 LEU A 180
TRP A 244
TYR A 100
 None
None
ACT  A1479 (-3.9A)
 0.86A 3aicG-5a2aA:
8.0		 3aicG-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		6 / 12 LEU A 177
ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
 None
ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
 0.73A 3aicH-5a2aA:
4.7		 3aicH-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 LEU A 180
TRP A 244
TYR A 100
 None
None
ACT  A1479 (-3.9A)
 0.89A 3aicH-5a2aA:
4.8		 3aicH-5a2aA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 6 GLN A 437
LEU A 435
GLU A 436
LEU A 471
 None
 0.85A 3h5gA-5a2aA:
undetectable
3h5gC-5a2aA:
undetectable		 3h5gA-5a2aA:
5.73
3h5gC-5a2aA:
5.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 8 ASP A 104
ASP A 213
ASP A 182
TYR A 193
 None
ACT  A1479 (-2.6A)
CA  A1480 (-2.4A)
None
 1.20A 3havA-5a2aA:
undetectable		 3havA-5a2aA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 THR A 273
LYS A 216
GLU A 270
 None
 0.82A 3ijdB-5a2aA:
10.8		 3ijdB-5a2aA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 6 ASP A 213
THR A 141
ILE A 102
PHE A 136
 ACT  A1479 (-2.6A)
None
None
None
 1.06A 4acbC-5a2aA:
2.8		 4acbC-5a2aA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVV_A_CPFA1081_1
(APOLIPOPROTEIN(A))		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		5 / 9 HIS A 217
THR A 214
ASP A 310
ASP A 358
LEU A 180
 None
ACT  A1479 ( 4.2A)
ACT  A1479 ( 4.9A)
ACT  A1478 (-2.7A)
None
 1.46A 4bvvA-5a2aA:
undetectable		 4bvvA-5a2aA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 6 GLY A  99
ASN A  92
TYR A  61
GLY A  64
 None
None
None
CA  A1481 ( 4.9A)
 0.85A 4fjpA-5a2aA:
undetectable		 4fjpA-5a2aA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 ARG A  41
HIS A  62
TYR A  97
 None
 1.32A 4fu8A-5a2aA:
undetectable		 4fu8A-5a2aA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 7 ILE A 342
PRO A 343
ARG A 384
GLY A 381
 None
 0.98A 4g0uB-5a2aA:
undetectable		 4g0uB-5a2aA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 5 PRO A 343
GLY A 341
ASP A 135
ASP A 264
 None
 1.13A 4n48B-5a2aA:
undetectable		 4n48B-5a2aA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 5 ILE A  89
HIS A 140
TYR A 193
VAL A 197
 None
ACT  A1479 (-4.4A)
None
None
 0.98A 4s0vA-5a2aA:
undetectable		 4s0vA-5a2aA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 5 LEU A 380
TYR A 376
ALA A 466
ILE A 420
 None
 1.17A 4y03B-5a2aA:
undetectable		 4y03B-5a2aA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		5 / 12 ARG A 211
ASP A 213
GLU A 242
HIS A 309
ASP A 310
 ACT  A1479 ( 4.9A)
ACT  A1479 (-2.6A)
ACT  A1479 ( 4.5A)
None
ACT  A1479 ( 4.9A)
 0.46A 5csyB-5a2aA:
5.9		 5csyB-5a2aA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		5 / 12 LEU A 445
LEU A 306
ILE A 274
ALA A 339
LEU A 285
 None
 1.22A 5ienA-5a2aA:
2.9		 5ienA-5a2aA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		5 / 12 LEU A 445
LEU A 306
ILE A 274
ALA A 339
LEU A 285
 None
 1.21A 5ienB-5a2aA:
2.9		 5ienB-5a2aA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 5 ILE A  69
LYS A 127
HIS A 126
VAL A 132
 None
 1.01A 5jmnA-5a2aA:
undetectable		 5jmnA-5a2aA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 7 GLY A 209
ASP A 236
HIS A 126
ASP A 208
 None
 1.03A 5nnwD-5a2aA:
undetectable		 5nnwD-5a2aA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 7 GLY A 209
ASP A 236
HIS A 126
ASP A 208
 None
 1.02A 5no9D-5a2aA:
undetectable		 5no9D-5a2aA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_SALA601_1
(SALICYLATE-AMP
LIGASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		5 / 9 HIS A 111
ASN A  49
PHE A 112
VAL A  39
GLY A  64
 None
CA  A1481 (-3.3A)
None
None
CA  A1481 ( 4.9A)
 1.17A 5wm2A-5a2aA:
2.2		 5wm2A-5a2aA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		8 / 12 TYR A 100
HIS A 140
LEU A 177
ASP A 213
LYS A 216
HIS A 217
HIS A 309
ASP A 310
 ACT  A1479 (-3.9A)
ACT  A1479 (-4.4A)
None
ACT  A1479 (-2.6A)
None
None
None
ACT  A1479 ( 4.9A)
 0.55A 6ag0A-5a2aA:
29.1		 6ag0A-5a2aA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		6 / 12 LEU A 177
ASP A 213
LYS A 216
HIS A 217
HIS A 309
ASP A 310
 None
ACT  A1479 (-2.6A)
None
None
None
ACT  A1479 ( 4.9A)
 0.45A 6ag0C-5a2aA:
29.0		 6ag0C-5a2aA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 ARG A 442
LYS A 439
TYR A 457
 None
 1.17A 6gnaA-5a2aA:
undetectable		 6gnaA-5a2aA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		3 / 3 ARG A 442
LYS A 439
TYR A 457
 None
 1.17A 6gnbA-5a2aA:
undetectable		 6gnbA-5a2aA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES
(Anoxybacillus
ayderensis) 		4 / 6 LYS A 228
PHE A 222
LEU A 239
PHE A 237
 None
 1.24A 6nmpC-5a2aA:
undetectable
6nmpJ-5a2aA:
undetectable		 6nmpC-5a2aA:
19.09
6nmpJ-5a2aA:
9.46