SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a2f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5a2f CD166 ANTIGEN
(Homo
sapiens) 		5 / 12 ILE A  40
ILE A  41
ALA A 103
VAL A  31
VAL A 128
 None
 1.07A 3rukB-5a2fA:
undetectable		 3rukB-5a2fA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5a2f CD166 ANTIGEN
(Homo
sapiens) 		5 / 12 ILE A  40
ILE A  41
ALA A 103
VAL A  31
VAL A 128
 None
 1.15A 4nkvC-5a2fA:
undetectable		 4nkvC-5a2fA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5a2f CD166 ANTIGEN
(Homo
sapiens) 		5 / 12 ILE A  40
ILE A  41
ALA A 103
VAL A  31
VAL A 128
 None
 1.15A 4nkvD-5a2fA:
undetectable		 4nkvD-5a2fA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 5a2f CD166 ANTIGEN
(Homo
sapiens) 		5 / 12 TYR A  29
THR A 126
VAL A  31
LEU A 115
TRP A  56
 None
 1.04A 5nz0A-5a2fA:
undetectable		 5nz0A-5a2fA:
17.06