SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a2o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 7 LEU A 153
THR A  47
ASN A  54
TYR A 221
 None
 1.22A 1afsA-5a2oA:
undetectable		 1afsA-5a2oA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 7 LEU A 153
THR A  47
ASN A  54
TYR A 221
 None
 1.22A 1afsB-5a2oA:
undetectable		 1afsB-5a2oA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 7 ARG A 243
TYR A 242
PHE A 170
PHE A 235
 None
 1.02A 1e71M-5a2oA:
undetectable		 1e71M-5a2oA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 7 ARG A 243
TYR A 242
PHE A 170
PHE A 235
 None
 1.03A 1e72M-5a2oA:
undetectable		 1e72M-5a2oA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 8 LEU A 153
TYR A  58
GLY A  52
TYR A 154
 None
 0.77A 1jlfA-5a2oA:
undetectable
1jlfB-5a2oA:
undetectable		 1jlfA-5a2oA:
22.11
1jlfB-5a2oA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 7 LEU A 153
TYR A  58
GLY A  52
TYR A 154
 None
 0.70A 1lweA-5a2oA:
undetectable		 1lweA-5a2oA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 8 LEU A 153
TYR A  58
GLY A  52
TYR A 154
 None
 0.69A 1s1xA-5a2oA:
undetectable		 1s1xA-5a2oA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 12 GLY A 430
ILE A 479
VAL A 548
PHE A 513
ALA A 553
 None
 1.24A 1vq1A-5a2oA:
undetectable		 1vq1A-5a2oA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 11 LEU A 153
LEU A 149
VAL A 113
GLY A 222
TYR A  58
 None
 1.45A 1y4lB-5a2oA:
undetectable		 1y4lB-5a2oA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 7 GLU A 368
ASN A  54
PRO A 381
ALA A 382
 None
 1.44A 2ejgB-5a2oA:
undetectable		 2ejgB-5a2oA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 12 ALA A 397
GLY A 473
LEU A 393
VAL A 389
TYR A 388
 None
 1.17A 2zifB-5a2oA:
undetectable		 2zifB-5a2oA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 5 ASN A 198
ALA A 385
LEU A 470
GLY A 391
THR A 481
 None
 1.39A 3dl9A-5a2oA:
undetectable		 3dl9A-5a2oA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 7 ARG A 372
MET A 384
ILE A 379
ILE A 374
 None
 0.97A 3hgxA-5a2oA:
2.3		 3hgxA-5a2oA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		3 / 3 GLU A 522
GLY A 526
THR A 525
 None
 0.46A 3iazA-5a2oA:
undetectable		 3iazA-5a2oA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 8 ILE A 197
PHE A 190
VAL A 167
GLY A 171
 None
 0.81A 4acaC-5a2oA:
undetectable		 4acaC-5a2oA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 8 ILE A 197
PHE A 190
VAL A 167
GLY A 171
 None
 0.81A 4acbC-5a2oA:
undetectable		 4acbC-5a2oA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 10 PHE A 512
SER A 515
LEU A 509
GLY A 510
ALA A 256
 None
 1.29A 4fe1A-5a2oA:
undetectable
4fe1J-5a2oA:
undetectable		 4fe1A-5a2oA:
22.21
4fe1J-5a2oA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 10 ALA A 437
VAL A 548
ILE A 532
ALA A 357
THR A 361
 None
 1.08A 4j14A-5a2oA:
undetectable		 4j14A-5a2oA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 9 ALA A 227
ALA A 225
ALA A 110
ALA A 231
SER A 233
 None
 1.24A 4twdA-5a2oA:
1.5
4twdB-5a2oA:
1.6
4twdC-5a2oA:
1.7
4twdD-5a2oA:
1.7
4twdE-5a2oA:
1.7		 4twdA-5a2oA:
19.55
4twdB-5a2oA:
19.55
4twdC-5a2oA:
19.55
4twdD-5a2oA:
19.55
4twdE-5a2oA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 8 PHE A 429
ALA A 477
LEU A 478
GLY A 426
 None
 0.81A 4xk8a-5a2oA:
undetectable		 4xk8a-5a2oA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 12 ILE A 474
ALA A 477
ALA A 397
LEU A 394
PHE A 429
 None
 1.36A 4zo1X-5a2oA:
undetectable		 4zo1X-5a2oA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 8 SER A  81
GLY A  79
ALA A  70
PHE A 511
 None
 0.68A 5albL-5a2oA:
undetectable		 5albL-5a2oA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 9 PHE A 352
GLY A 482
ARG A 422
ALA A 477
GLY A 426
 None
 1.39A 5l8rA-5a2oA:
undetectable		 5l8rA-5a2oA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 10 VAL A 518
GLU A 522
LEU A 465
ALA A  71
THR A 369
 None
 1.30A 5mm4B-5a2oA:
undetectable		 5mm4B-5a2oA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 5 TYR A 469
SER A 383
ALA A 382
THR A  57
 None
 1.22A 5n0tA-5a2oA:
undetectable		 5n0tA-5a2oA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 5 TYR A 469
SER A 383
ALA A 382
THR A  57
 None
 1.22A 5n0wB-5a2oA:
undetectable		 5n0wB-5a2oA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		4 / 5 TYR A 469
SER A 383
ALA A 382
THR A  57
 None
 1.30A 5n4iA-5a2oA:
undetectable		 5n4iA-5a2oA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 12 LEU A 155
LEU A 158
GLY A 159
GLY A 161
VAL A 163
 None
 0.97A 5uc1A-5a2oA:
undetectable		 5uc1A-5a2oA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		5 / 12 LEU A 155
LEU A 158
GLY A 159
GLY A 161
VAL A 163
 None
 0.99A 5uc1B-5a2oA:
undetectable		 5uc1B-5a2oA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5a2o NITRATE TRANSPORTER
1.1
(Arabidopsis
thaliana) 		3 / 3 THR A  60
MET A  63
HIS A  64
 None
 0.81A 5uunA-5a2oA:
undetectable		 5uunA-5a2oA:
17.92