SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		5 / 11 LEU A 300
LEU A 306
ALA A 327
VAL A 307
ARG A 272
 None
None
AGS  A1529 (-3.7A)
None
None
 1.42A 1kt6A-5a30A:
undetectable		 1kt6A-5a30A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		5 / 11 LEU A 300
LEU A 306
ALA A 327
VAL A 307
ARG A 272
 None
None
AGS  A1529 (-3.7A)
None
None
 1.37A 1kt7A-5a30A:
undetectable		 1kt7A-5a30A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		3 / 3 PHE A 474
LEU A 393
MET A 379
 None
 0.88A 1mx1D-5a30A:
1.8		 1mx1D-5a30A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		3 / 3 ASN A 453
TRP A 471
GLN A 383
 None
 1.30A 1xoqA-5a30A:
undetectable		 1xoqA-5a30A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		5 / 12 LEU A 334
LEU A 396
LEU A 393
LEU A 454
ILE A 390
 None
 1.05A 2ouzA-5a30A:
undetectable		 2ouzA-5a30A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		4 / 6 PHE A 309
TYR A 293
LEU A 207
VAL A 238
 None
 0.91A 2zuhA-5a30A:
undetectable		 2zuhA-5a30A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		3 / 3 CYH A 413
HIS A 406
PHE A 415
 None
 0.70A 3cr4X-5a30A:
1.1		 3cr4X-5a30A:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		3 / 3 ALA A 204
THR A 314
CYH A 318
 None
 0.78A 3e4eA-5a30A:
undetectable		 3e4eA-5a30A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		5 / 9 ILE A 107
ILE A  92
LEU A  83
GLU A  79
LEU A  82
 None
 1.20A 3f78A-5a30A:
undetectable		 3f78A-5a30A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		5 / 9 ILE A 107
ILE A  92
LEU A  83
GLU A  79
LEU A  82
 None
 1.19A 3f78B-5a30A:
undetectable		 3f78B-5a30A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		5 / 10 SER A 227
GLY A 225
PRO A 223
SER A 321
LEU A 320
 None
AGS  A1529 (-3.6A)
None
None
None
 1.30A 3lsfB-5a30A:
undetectable
3lsfE-5a30A:
undetectable		 3lsfB-5a30A:
22.16
3lsfE-5a30A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		3 / 3 ASN A 453
TRP A 471
ASP A 394
 None
 1.23A 4a7tA-5a30A:
undetectable
4a7tF-5a30A:
undetectable		 4a7tA-5a30A:
15.56
4a7tF-5a30A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		5 / 12 LEU A 174
LEU A 520
LEU A 435
ILE A 171
HIS A 358
 None
 1.26A 4f4dA-5a30A:
undetectable		 4f4dA-5a30A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		3 / 3 TYR A 135
GLY A 290
PRO A 291
 None
 0.60A 4qwpA-5a30A:
undetectable		 4qwpA-5a30A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		4 / 8 TYR A 202
THR A 230
CYH A 236
LEU A 193
 None
 1.43A 5kxiD-5a30A:
undetectable
5kxiE-5a30A:
undetectable		 5kxiD-5a30A:
22.24
5kxiE-5a30A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5a30 MITOCHONDRIAL
PROTEIN
(Gallus
gallus) 		3 / 3 ILE A 378
ASN A 229
CYH A 339
 None
 0.86A 6bp4A-5a30A:
undetectable		 6bp4A-5a30A:
18.83