SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 5a33 RNA2 POLYPROTEIN
(Cowpea
mosaic
virus) 		5 / 12 VAL A 161
LEU A  74
ILE A  39
GLY A  37
LEU A  34
 None
 1.02A 1cqeA-5a33A:
undetectable		 1cqeA-5a33A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 5a33 RNA2 POLYPROTEIN
(Cowpea
mosaic
virus) 		5 / 12 VAL A 161
LEU A  74
ILE A  39
GLY A  37
LEU A  34
 None
 1.02A 1cqeB-5a33A:
undetectable		 1cqeB-5a33A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5a33 RNA2 POLYPROTEIN
(Cowpea
mosaic
virus) 		5 / 12 VAL A 161
LEU A  74
ILE A  39
GLY A  37
LEU A  34
 None
 0.98A 1eqhB-5a33A:
undetectable		 1eqhB-5a33A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5a33 RNA2 POLYPROTEIN
(Cowpea
mosaic
virus) 		5 / 12 VAL A 161
LEU A  74
ILE A  39
GLY A  37
LEU A  34
 None
 0.97A 2aylB-5a33A:
undetectable		 2aylB-5a33A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 5a33 RNA2 POLYPROTEIN
(Cowpea
mosaic
virus) 		4 / 6 VAL A 149
ASN A 152
PRO A 153
ILE A 156
 None
 1.14A 6h7uA-5a33A:
undetectable		 6h7uA-5a33A:
17.01