SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 5a3g M50
(Murid
betaherpesvirus
1) 		4 / 4 LEU A  96
PRO A  93
LEU A  99
ARG A 101
 None
 1.41A 1hrkB-5a3gA:
undetectable		 1hrkB-5a3gA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 5a3g M50
(Murid
betaherpesvirus
1) 		6 / 12 PHE A  75
ILE A  54
ILE A  21
THR A  51
VAL A  84
SER A  85
 None
 1.48A 1sg9A-5a3gA:
undetectable		 1sg9A-5a3gA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5a3g M50
(Murid
betaherpesvirus
1) 		4 / 4 LEU A  96
PRO A  93
LEU A  99
ARG A 101
 None
 1.40A 2hrcB-5a3gA:
undetectable		 2hrcB-5a3gA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5a3g M50
(Murid
betaherpesvirus
1) 		4 / 4 LEU A  96
PRO A  93
LEU A  99
ARG A 101
 None
 1.45A 2pnjB-5a3gA:
undetectable		 2pnjB-5a3gA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5a3g M50
(Murid
betaherpesvirus
1) 		4 / 4 PRO A  57
LEU A 164
ILE A 168
ARG A 171
 None
 1.28A 3w1wA-5a3gA:
undetectable		 3w1wA-5a3gA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 5a3g M50
(Murid
betaherpesvirus
1) 		4 / 6 ARG A  83
GLY A  81
SER A  85
VAL A 110
 None
 1.16A 5ysiA-5a3gA:
undetectable		 5ysiA-5a3gA:
21.99