SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FPQ_A_SAMA1699_0
(ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 CYH A 228
GLY A 135
LEU A 290
VAL A 296
ALA A 141
 None
 1.29A 1fpqA-5a3jA:
6.1		 1fpqA-5a3jA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 284
LEU A 136
ARG A 119
ALA A 129
ALA A  42
 None
 1.17A 2bm9D-5a3jA:
5.5		 2bm9D-5a3jA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 169
GLY A 167
ALA A 163
THR A 186
ALA A 185
ALA A 172
 None
 1.26A 2gluB-5a3jA:
7.8		 2gluB-5a3jA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 THR A  43
THR A 116
LEU A  40
LEU A  38
GLY A  75
 None
 1.34A 4c9pA-5a3jA:
undetectable		 4c9pA-5a3jA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 THR A  43
THR A 116
LEU A  40
LEU A  38
GLY A  75
 None
 1.33A 4c9pB-5a3jA:
undetectable		 4c9pB-5a3jA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 MET A 287
LEU A 290
LEU A 139
ALA A 179
LEU A 178
 None
 1.46A 4m11A-5a3jA:
undetectable		 4m11A-5a3jA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 GLY A  16
GLY A  17
ALA A  19
ILE A 317
 None
 0.72A 4yjiA-5a3jA:
undetectable		 4yjiA-5a3jA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ALA A  74
ALA A  42
GLY A 103
ALA A  70
ASP A  72
 None
 1.11A 5l5zK-5a3jA:
undetectable
5l5zL-5a3jA:
undetectable		 5l5zK-5a3jA:
21.15
5l5zL-5a3jA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ALA A  74
ALA A  42
GLY A 103
ALA A  70
ASP A  72
 None
 1.10A 5l5zY-5a3jA:
undetectable
5l5zZ-5a3jA:
undetectable		 5l5zY-5a3jA:
21.15
5l5zZ-5a3jA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 284
VAL A  94
ALA A  42
ALA A  74
GLY A  75
 None
 0.79A 5tzoB-5a3jA:
undetectable		 5tzoB-5a3jA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 250
ALA A 229
ILE A 159
LEU A 142
ILE A 248
 None
 1.07A 7dfrA-5a3jA:
2.4		 7dfrA-5a3jA:
19.34