SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a3m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 5a3m CEA1
(Komagataella
pastoris) 		3 / 3 ASP A 137
PHE A  67
ASN A  57
 NAG  A 501 ( 2.5A)
None
None
 0.88A 1sg9B-5a3mA:
undetectable		 1sg9B-5a3mA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 5a3m CEA1
(Komagataella
pastoris) 		4 / 6 ALA A 207
PHE A  89
ASN A 202
ASP A 137
 None
None
CA  A 500 (-3.0A)
NAG  A 501 ( 2.5A)
 1.00A 1yc2A-5a3mA:
undetectable		 1yc2A-5a3mA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 5a3m CEA1
(Komagataella
pastoris) 		4 / 5 ALA A 207
PHE A  89
ASN A 202
ASP A 137
 None
None
CA  A 500 (-3.0A)
NAG  A 501 ( 2.5A)
 1.14A 1yc2D-5a3mA:
undetectable		 1yc2D-5a3mA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 5a3m CEA1
(Komagataella
pastoris) 		4 / 6 ASP A  58
ARG A  75
ILE A  62
SER A 174
 None
PEG  A1243 (-3.6A)
None
None
 1.41A 3ckzA-5a3mA:
undetectable		 3ckzA-5a3mA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 5a3m CEA1
(Komagataella
pastoris) 		4 / 6 ALA A  49
ILE A  51
VAL A 104
ASN A  79
 None
 1.11A 3nneG-5a3mA:
undetectable		 3nneG-5a3mA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5a3m CEA1
(Komagataella
pastoris) 		4 / 7 PRO A 216
VAL A 124
ALA A 122
PHE A 120
 None
 1.05A 4lb2A-5a3mA:
undetectable		 4lb2A-5a3mA:
16.96