SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a42'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ALA A1303
VAL A1308
TRP A1252
 None
 0.90A 1c4dC-5a42A:
undetectable
1c4dD-5a42A:
undetectable		 1c4dC-5a42A:
1.05
1c4dD-5a42A:
1.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 PHE A1240
LEU A1283
VAL A1315
VAL A1257
 None
 0.89A 1e7aB-5a42A:
undetectable		 1e7aB-5a42A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 10 LEU A1075
THR A1044
ILE A1022
PHE A1084
THR A1040
 None
 1.25A 1i18A-5a42A:
undetectable
1i18B-5a42A:
undetectable		 1i18A-5a42A:
4.58
1i18B-5a42A:
4.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 10 PHE A1084
THR A1040
LEU A1075
THR A1044
ILE A1022
 None
 1.25A 1i18A-5a42A:
undetectable
1i18B-5a42A:
undetectable		 1i18A-5a42A:
4.58
1i18B-5a42A:
4.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ARG A1219
ARG A1436
ARG A1220
 None
 1.09A 1l7fA-5a42A:
undetectable		 1l7fA-5a42A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ARG A1219
ARG A1436
ARG A1220
 None
 1.09A 1l7hA-5a42A:
undetectable		 1l7hA-5a42A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A1650
GLY A1554
THR A1623
SER A1037
PRO A1653
 None
 1.09A 1sg9A-5a42A:
undetectable		 1sg9A-5a42A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 4 THR A1158
GLY A1034
ASP A1035
ALA A1126
 None
 1.26A 1sg9A-5a42A:
undetectable		 1sg9A-5a42A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 PHE A 544
PRO A 615
ILE A 608
GLY A 545
ALA A 731
 None
 1.05A 1sg9C-5a42A:
undetectable		 1sg9C-5a42A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 THR A1004
PHE A1008
PHE A 388
GLY A 414
 None
 1.09A 1ykiA-5a42A:
undetectable
1ykiB-5a42A:
undetectable		 1ykiA-5a42A:
9.00
1ykiB-5a42A:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 THR A1004
PHE A1008
PHE A 388
GLY A 414
 None
 1.08A 1ykiC-5a42A:
undetectable
1ykiD-5a42A:
undetectable		 1ykiC-5a42A:
9.00
1ykiD-5a42A:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ASP A1259
PHE A1196
ARG A1263
 None
 0.83A 2a3aA-5a42A:
undetectable		 2a3aA-5a42A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 11 THR A1425
GLU A1632
ALA A1129
ASP A1596
PRO A1184
 None
 1.16A 2admB-5a42A:
undetectable		 2admB-5a42A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 4 VAL A 845
LEU A 303
ILE A 305
LEU A 364
 None
 0.98A 2byoA-5a42A:
0.6		 2byoA-5a42A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 11 LEU A1423
LEU A1386
LEU A1413
LEU A1431
ARG A1175
 None
 1.06A 2ceoA-5a42A:
undetectable		 2ceoA-5a42A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A 422
LEU A 424
GLY A 407
ASN A 406
GLN A 971
 None
 1.18A 2e7fB-5a42A:
undetectable		 2e7fB-5a42A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 TRP A1252
ALA A1303
VAL A1308
 None
 0.95A 2izqC-5a42A:
undetectable
2izqD-5a42A:
undetectable		 2izqC-5a42A:
1.05
2izqD-5a42A:
1.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 THR A1620
GLU A1556
PHE A1030
ILE A1121
 None
 1.04A 2w98B-5a42A:
undetectable		 2w98B-5a42A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WET_B_TRPB650_0
(TRYPTOPHAN
5-HALOGENASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 10 SER A 591
THR A 601
GLN A 589
GLN A 526
GLU A 953
 None
 1.16A 2wetB-5a42A:
0.0		 2wetB-5a42A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A 422
LEU A 424
GLY A 407
ASN A 406
GLN A 971
 None
 1.21A 2ycjA-5a42A:
undetectable		 2ycjA-5a42A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A 777
GLY A 785
GLY A 783
ALA A 779
ALA A 314
 None
 1.06A 2yvlA-5a42A:
undetectable		 2yvlA-5a42A:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A 777
GLY A 785
GLY A 783
ALA A 779
ALA A 314
 None
 1.05A 2yvlB-5a42A:
undetectable		 2yvlB-5a42A:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A 777
GLY A 785
GLY A 783
ALA A 779
ALA A 314
 None
 1.04A 2yvlD-5a42A:
undetectable		 2yvlD-5a42A:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 LEU A1569
ILE A1511
ARG A1509
TRP A1533
 None
 1.50A 2zlcA-5a42A:
undetectable		 2zlcA-5a42A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 GLN A1319
GLY A1265
ARG A1263
LEU A1199
 None
 1.03A 3bjwE-5a42A:
undetectable		 3bjwE-5a42A:
5.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 10 VAL A 508
PHE A 588
LEU A 561
THR A 562
THR A 522
 None
 1.48A 3dazA-5a42A:
undetectable		 3dazA-5a42A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 10 VAL A 508
PHE A 588
LEU A 561
THR A 562
THR A 522
 None
 1.46A 3dcsA-5a42A:
undetectable		 3dcsA-5a42A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 4 GLY A 664
VAL A 662
GLY A 710
THR A 709
 None
 0.91A 3ib2A-5a42A:
undetectable		 3ib2A-5a42A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_A_KANA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 11 VAL A1532
GLN A1560
ALA A1567
GLU A1570
SER A1568
 None
 1.25A 3kp5A-5a42A:
undetectable		 3kp5A-5a42A:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 TRP A1252
ALA A1303
VAL A1308
 None
 0.95A 3l8lC-5a42A:
undetectable
3l8lD-5a42A:
undetectable		 3l8lC-5a42A:
1.05
3l8lD-5a42A:
2.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 HIS A 297
LEU A 762
LEU A 850
SER A 826
 None
 0.99A 3lm8B-5a42A:
5.3
3lm8D-5a42A:
5.3		 3lm8B-5a42A:
8.48
3lm8D-5a42A:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 9 VAL A 294
ALA A 355
GLU A 320
ALA A 334
THR A 335
 None
 1.14A 3mdvA-5a42A:
undetectable		 3mdvA-5a42A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 TRP A 915
GLU A 855
SER A 625
THR A 634
 None
 1.46A 3ropA-5a42A:
undetectable		 3ropA-5a42A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 ASP A 564
SER A 507
VAL A 508
GLY A 567
 None
 1.07A 3rxhA-5a42A:
undetectable		 3rxhA-5a42A:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ARG A1029
PRO A1552
PHE A1030
 None
 0.97A 3thrC-5a42A:
undetectable		 3thrC-5a42A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ASP A 900
GLU A 995
GLY A 994
 None
 0.58A 3w9tA-5a42A:
undetectable		 3w9tA-5a42A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ASP A 411
ARG A 857
LYS A 415
 None
 1.11A 3wipG-5a42A:
undetectable		 3wipG-5a42A:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 7 PHE A 240
VAL A 187
GLY A 184
PHE A 199
 None
 1.01A 4ejjB-5a42A:
undetectable		 4ejjB-5a42A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 HIS A 849
ILE A 378
LEU A 371
GLY A 846
TYR A 786
 None
 1.14A 4foxB-5a42A:
undetectable		 4foxB-5a42A:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 ALA A1018
ILE A1022
LEU A1046
ASN A 993
 None
 0.83A 4g19A-5a42A:
undetectable		 4g19A-5a42A:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 7 ALA A1417
GLU A1179
LEU A1423
LEU A1431
 None
 0.99A 4iomA-5a42A:
undetectable		 4iomA-5a42A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 PRO A 393
ASN A 406
HIS A 447
 None
 0.74A 4ma3H-5a42A:
6.2
4ma3L-5a42A:
undetectable		 4ma3H-5a42A:
8.88
4ma3L-5a42A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 TYR A 299
LEU A 373
ASP A 930
VAL A 758
 None
 1.23A 4nkvA-5a42A:
undetectable		 4nkvA-5a42A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 THR A1040
THR A1082
ASP A1042
TYR A 511
 None
 1.40A 4oltA-5a42A:
undetectable		 4oltA-5a42A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 THR A1040
THR A1082
ASP A1042
TYR A 511
 None
 1.38A 4oltB-5a42A:
undetectable		 4oltB-5a42A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 7 LEU A 850
THR A 827
LEU A 823
SER A 791
 None
 0.82A 4pwjB-5a42A:
5.8		 4pwjB-5a42A:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 THR A1040
THR A1082
ASP A1042
TYR A 511
 None
 1.38A 4qwpA-5a42A:
undetectable		 4qwpA-5a42A:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A 879
ALA A1002
GLN A1001
THR A 911
LEU A 863
 None
 1.02A 4qzuA-5a42A:
undetectable		 4qzuA-5a42A:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A 879
ALA A1002
GLN A1001
THR A 911
LEU A 863
 None
 1.05A 4qzuC-5a42A:
undetectable		 4qzuC-5a42A:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_1
(RETINOL-BINDING
PROTEIN 2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 LYS A 922
TRP A 915
GLN A 916
 None
 1.10A 4qzuC-5a42A:
0.0		 4qzuC-5a42A:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 GLU A 793
ARG A 820
GLN A 471
 None
 0.97A 4rtbA-5a42A:
undetectable		 4rtbA-5a42A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 SER A 750
ALA A 752
VAL A 753
 None
 0.58A 4x1iA-5a42A:
undetectable		 4x1iA-5a42A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 7 SER A1424
ARG A1371
SER A1384
GLU A1427
 None
 1.33A 4xzkA-5a42A:
undetectable		 4xzkA-5a42A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 7 VAL A1021
GLN A1115
LEU A1105
GLU A1110
 None
 1.09A 4zphA-5a42A:
undetectable
4zphB-5a42A:
undetectable		 4zphA-5a42A:
13.78
4zphB-5a42A:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 7 LEU A 850
THR A 827
LEU A 823
SER A 791
 None
 0.84A 5bojB-5a42A:
3.0		 5bojB-5a42A:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 11 ALA A1434
LEU A1393
MET A1392
LEU A1395
LEU A1386
 None
 1.10A 5dxbB-5a42A:
undetectable		 5dxbB-5a42A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 10 ALA A1434
LEU A1393
MET A1392
LEU A1395
LEU A1386
 None
 1.13A 5dxeB-5a42A:
undetectable		 5dxeB-5a42A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 11 ALA A1434
LEU A1393
MET A1392
LEU A1395
LEU A1386
 None
 1.13A 5dxgB-5a42A:
undetectable		 5dxgB-5a42A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 SER A 750
ALA A 752
VAL A 753
 None
 0.56A 5eypA-5a42A:
undetectable		 5eypA-5a42A:
14.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 SER A1414
ASN A1478
VAL A1476
ALA A1461
LEU A1165
 None
 1.10A 5kocA-5a42A:
undetectable		 5kocA-5a42A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 LEU A 527
GLY A 590
GLY A 525
LEU A 491
ALA A 604
 None
 1.02A 5l0zA-5a42A:
undetectable		 5l0zA-5a42A:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 ASP A1381
TYR A1311
SER A1428
SER A1339
 None
 1.01A 5l1fA-5a42A:
undetectable
5l1fB-5a42A:
undetectable		 5l1fA-5a42A:
19.94
5l1fB-5a42A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 TRP A 743
SER A 742
GLY A 740
GLY A 719
ARG A 674
 None
 1.01A 5o4yD-5a42A:
undetectable
5o4yE-5a42A:
6.8		 5o4yD-5a42A:
1.99
5o4yE-5a42A:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A1177
PHE A1260
ILE A1225
LEU A1195
ALA A1192
 None
 1.26A 5oy02-5a42A:
2.2		 5oy02-5a42A:
3.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 HIS A 300
SER A 792
ARG A 923
 None
 1.00A 5u63A-5a42A:
undetectable		 5u63A-5a42A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ALA A 604
ARG A 602
PHE A 588
GLY A 590
GLY A 525
 None
 1.18A 5ul4A-5a42A:
undetectable		 5ul4A-5a42A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 GLU A1250
ARG A1371
VAL A1308
TRP A1252
 None
 1.38A 5unxA-5a42A:
undetectable
5unxB-5a42A:
undetectable		 5unxA-5a42A:
14.02
5unxB-5a42A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 ALA A 334
THR A 332
THR A 330
ALA A 351
 None
 0.86A 5x2tI-5a42A:
undetectable
5x2tJ-5a42A:
undetectable
5x2tK-5a42A:
undetectable
5x2tL-5a42A:
undetectable		 5x2tI-5a42A:
6.48
5x2tJ-5a42A:
7.08
5x2tK-5a42A:
6.48
5x2tL-5a42A:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 PHE A 200
LEU A 289
GLY A 266
LEU A 229
ARG A 201
 None
 1.16A 6bxmA-5a42A:
undetectable		 6bxmA-5a42A:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ILE A1098
THR A1620
VAL A1619
VAL A1651
GLU A1024
 None
 1.30A 6bzoC-5a42A:
undetectable		 6bzoC-5a42A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 LEU A1283
TYR A1286
GLU A1249
ASN A1237
 None
 1.20A 6c71B-5a42A:
undetectable		 6c71B-5a42A:
4.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 TRP A1144
GLY A1167
ALA A1137
LEU A1486
 None
 0.95A 6fosA-5a42A:
2.5		 6fosA-5a42A:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 PHE A 621
PHE A 648
VAL A 716
SER A 644
 None
 1.14A 6huoC-5a42A:
3.3
6huoD-5a42A:
2.9		 6huoC-5a42A:
4.70
6huoD-5a42A:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 GLY A 785
LEU A 828
SER A 295
GLN A 308
 None
 1.35A 6ji6A-5a42A:
4.3		 6ji6A-5a42A:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 GLY A 785
SER A 295
TYR A 932
GLN A 308
 None
 1.25A 6ji6A-5a42A:
4.3		 6ji6A-5a42A:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ASN A 729
PRO A 728
GLN A 666
 None
 0.88A 6jnhA-5a42A:
undetectable		 6jnhA-5a42A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ASN A 729
PRO A 728
GLN A 666
 None
 0.91A 6jogA-5a42A:
undetectable		 6jogA-5a42A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 GLY A 340
LEU A 353
ILE A 319
HIS A 297
TYR A 299
 None
 1.40A 6md4A-5a42A:
undetectable		 6md4A-5a42A:
4.77