SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a49'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 5a49 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		3 / 3 ASP A 157
PHE A 198
ARG A 150
 None
 0.80A 2a3aA-5a49A:
undetectable		 2a3aA-5a49A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 5a49 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		5 / 11 PHE A 189
LEU A 184
ILE A 163
GLU A 159
ASP A 157
 None
 1.39A 3ko0A-5a49A:
undetectable
3ko0B-5a49A:
undetectable
3ko0C-5a49A:
undetectable
3ko0D-5a49A:
undetectable		 3ko0A-5a49A:
20.59
3ko0B-5a49A:
20.59
3ko0C-5a49A:
20.59
3ko0D-5a49A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 5a49 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		4 / 5 ARG A 161
LEU A 164
VAL A 205
ASP A 157
 None
 1.17A 3ufnA-5a49A:
undetectable
3ufnB-5a49A:
undetectable		 3ufnA-5a49A:
22.22
3ufnB-5a49A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 5a49 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		4 / 5 ILE A 156
ILE A 177
TYR A 181
GLU A 180
 None
 1.16A 4a99D-5a49A:
undetectable		 4a99D-5a49A:
14.11