SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 5a51 AT3G17980
(Arabidopsis
thaliana) 		3 / 3 SER A 107
ASP A  56
ASP A 110
 None
CA  A1196 (-3.4A)
CA  A1195 ( 4.5A)
 0.74A 2plwA-5a51A:
undetectable		 2plwA-5a51A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 5a51 AT3G17980
(Arabidopsis
thaliana) 		5 / 11 LEU A 171
ALA A 115
LEU A  98
ALA A 181
VAL A 168
 None
 1.23A 3e22D-5a51A:
undetectable		 3e22D-5a51A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 5a51 AT3G17980
(Arabidopsis
thaliana) 		5 / 10 LEU A 150
ALA A 115
ASP A 114
VAL A 179
LEU A 169
 None
 1.01A 3ogqA-5a51A:
undetectable		 3ogqA-5a51A:
23.36