SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a52'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	5a52	CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN (Arabidopsis thaliana)	4 / 6	LEU A 18 ILE A 20 ASP A 27 PRO A 28	None None CA A1164 (-3.7A) None	0.86A	1ditH-5a52A: undetectable 1ditP-5a52A: undetectable	1ditH-5a52A: 20.99 1ditP-5a52A: 6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KUH_A_HLTA150_1 (CALMODULIN)	5a52	CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN (Arabidopsis thaliana)	4 / 6	LEU A 143 MET A 141 LEU A 124 GLU A 87	None	1.23A	2kuhA-5a52A: undetectable	2kuhA-5a52A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K7G_B_ACTB902_0 (3-HYDROXYPROLINE DEHYDRATSE)	5a52	CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN (Arabidopsis thaliana)	4 / 7	ASP A 27 SER A 24 HIS A 46 SER A 25	CA A1164 (-3.7A) None None None	1.15A	4k7gB-5a52A: undetectable	4k7gB-5a52A: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DV4_A_NMYA601_1 (CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE)	5a52	CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN (Arabidopsis thaliana)	5 / 12	LEU A 145 ASN A 53 LEU A 8 PHE A 88 ILE A 10	None	1.35A	5dv4A-5a52A: undetectable	5dv4A-5a52A: 16.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DIT_P_2PPP1_1","ALPHA-THROMBIN;PEPTIDE INHIBITOR CVS995","5a52","CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN","Arabidopsis thaliana",4,"LEU A  18;ILE A  20;ASP A  27;PRO A  28","None;None; CA A1164 (-3.7A);None","0.86A","1ditH-5a52A:undetectable;1ditP-5a52A:undetectable","1ditH-5a52A:20.99;1ditP-5a52A:6.02"],["2KUH_A_HLTA150_1","CALMODULIN","5a52","CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN","Arabidopsis thaliana",4,"LEU A 143;MET A 141;LEU A 124;GLU A  87","None","1.23A","2kuhA-5a52A:undetectable","2kuhA-5a52A:16.67"],["4K7G_B_ACTB902_0","3-HYDROXYPROLINE DEHYDRATSE","5a52","CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN","Arabidopsis thaliana",4,"ASP A  27;SER A  24;HIS A  46;SER A  25"," CA A1164 (-3.7A);None;None;None","1.15A","4k7gB-5a52A:undetectable","4k7gB-5a52A:17.03"],["5DV4_A_NMYA601_1","CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE","5a52","CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN","Arabidopsis thaliana",5,"LEU A 145;ASN A  53;LEU A   8;PHE A  88;ILE A  10","None","1.35A","5dv4A-5a52A:undetectable","5dv4A-5a52A:16.75"]]