SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DEB_B_MTXB302_1 (BIFUNCTIONAL PROTEIN FOLD)	5a6g	PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 (Gallus gallus)	6 / 12	LEU B 257 GLN B 324 LEU B 321 PRO B 322 PHE B 291 THR B 263	None	1.43A	6debB-5a6gB: undetectable	6debB-5a6gB: 24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DEB_B_MTXB302_1 (BIFUNCTIONAL PROTEIN FOLD)	5a6g	PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 (Gallus gallus)	5 / 12	LEU B 257 GLN B 324 LEU B 321 PRO B 322 THR B 263	None	1.26A	6debB-5a6gB: undetectable	6debB-5a6gB: 24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBV_D_FI8D1904_0 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	5a6g	PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 (Gallus gallus)	4 / 8	MET B 313 ILE B 312 THR B 290 VAL B 289	None	0.89A	6fbvC-5a6gB: undetectable	6fbvC-5a6gB: 5.79