SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a7d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 6 MET L 499
LEU L 587
ALA L 541
LEU L 539
 None
 0.74A 1etb1-5a7dL:
undetectable		 1etb1-5a7dL:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 5a7d PINS
(Drosophila
melanogaster) 		4 / 6 THR B 227
LEU B 224
GLY B 222
TYR B 201
 None
 1.22A 1gtiC-5a7dB:
1.2		 1gtiC-5a7dB:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 5a7d PINS
(Drosophila
melanogaster) 		4 / 4 ALA B 326
ARG B 294
GLN B 329
GLU B 330
 None
 1.36A 1lqtB-5a7dB:
undetectable		 1lqtB-5a7dB:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 5a7d PINS
(Drosophila
melanogaster) 		4 / 4 ALA B 326
ARG B 294
GLN B 329
GLU B 330
 None
 1.36A 1lquB-5a7dB:
undetectable		 1lquB-5a7dB:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5a7d INSCUTEABLE
PINS
(Drosophila
melanogaster) 		3 / 3 ARG B 339
VAL L 310
TRP L 313
 None
 0.87A 1qw6A-5a7dB:
undetectable		 1qw6A-5a7dB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5a7d INSCUTEABLE
PINS
(Drosophila
melanogaster) 		3 / 3 ARG B 339
VAL L 310
TRP L 313
 None
 0.94A 1qwcA-5a7dB:
undetectable		 1qwcA-5a7dB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 8 MET L 499
LEU L 587
ALA L 541
LEU L 539
 None
 0.72A 1sn5C-5a7dL:
undetectable		 1sn5C-5a7dL:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 5 LEU L 446
ALA L 379
LEU L 374
SER L 370
 None
 0.96A 1tt6B-5a7dL:
undetectable		 1tt6B-5a7dL:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 6 LEU L 446
ALA L 379
LEU L 374
SER L 370
 None
 0.94A 1tz8C-5a7dL:
undetectable
1tz8D-5a7dL:
undetectable		 1tz8C-5a7dL:
15.90
1tz8D-5a7dL:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 8 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.76A 1v54C-5a7dL:
6.6
1v54J-5a7dL:
undetectable		 1v54C-5a7dL:
19.25
1v54J-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 8 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.74A 1v54P-5a7dL:
6.6
1v54W-5a7dL:
undetectable		 1v54P-5a7dL:
19.25
1v54W-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5a7d INSCUTEABLE
PINS
(Drosophila
melanogaster) 		3 / 3 ARG B 339
VAL L 310
TRP L 313
 None
 0.94A 1vagA-5a7dB:
undetectable		 1vagA-5a7dB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5a7d INSCUTEABLE
PINS
(Drosophila
melanogaster) 		3 / 3 ARG B 339
VAL L 310
TRP L 313
 None
 0.99A 1zviA-5a7dB:
undetectable		 1zviA-5a7dB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 5 LEU L 587
LEU L 539
LEU L 522
LEU L 523
 None
 1.03A 2ab2B-5a7dL:
undetectable		 2ab2B-5a7dL:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 8 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.77A 2dyrC-5a7dL:
6.5
2dyrJ-5a7dL:
undetectable		 2dyrC-5a7dL:
19.25
2dyrJ-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 8 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.75A 2dyrP-5a7dL:
6.6
2dyrW-5a7dL:
undetectable		 2dyrP-5a7dL:
19.25
2dyrW-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.74A 2eikC-5a7dL:
6.5
2eikJ-5a7dL:
undetectable		 2eikC-5a7dL:
19.25
2eikJ-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 8 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.65A 2eikP-5a7dL:
6.6
2eikW-5a7dL:
undetectable		 2eikP-5a7dL:
19.25
2eikW-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 8 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.71A 2eilC-5a7dL:
6.7
2eilJ-5a7dL:
undetectable		 2eilC-5a7dL:
19.25
2eilJ-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5a7d INSCUTEABLE
PINS
(Drosophila
melanogaster) 		4 / 7 ARG B 339
TRP L 313
ASN B 266
ALA L 320
 None
 1.28A 2ejgB-5a7dB:
undetectable		 2ejgB-5a7dB:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.68A 3ag2C-5a7dL:
6.6		 3ag2C-5a7dL:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		5 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
PHE L 410
 None
 1.21A 3ag2P-5a7dL:
6.6
3ag2W-5a7dL:
undetectable		 3ag2P-5a7dL:
19.25
3ag2W-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 8 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.70A 3ag4C-5a7dL:
6.6
3ag4J-5a7dL:
undetectable		 3ag4C-5a7dL:
19.25
3ag4J-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.69A 3ag4P-5a7dL:
6.5
3ag4W-5a7dL:
undetectable		 3ag4P-5a7dL:
19.25
3ag4W-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.73A 3asnC-5a7dL:
6.5
3asnJ-5a7dL:
undetectable		 3asnC-5a7dL:
19.25
3asnJ-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5a7d PINS
INSCUTEABLE
(Drosophila
melanogaster;
Drosophila
melanogaster) 		4 / 6 PRO L 323
HIS B 172
LEU B 230
ALA L 320
 None
 0.93A 3gv1A-5a7dL:
undetectable
3gv1C-5a7dL:
undetectable		 3gv1A-5a7dL:
16.51
3gv1C-5a7dL:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5a7d PINS
INSCUTEABLE
(Drosophila
melanogaster;
Drosophila
melanogaster) 		4 / 6 LEU B 230
ALA L 320
PRO L 323
HIS B 172
 None
 0.99A 3gv1A-5a7dB:
undetectable
3gv1B-5a7dB:
undetectable		 3gv1A-5a7dB:
18.21
3gv1B-5a7dB:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5a7d INSCUTEABLE
PINS
(Drosophila
melanogaster) 		5 / 11 ALA B  82
ILE B  83
SER L 333
LEU B  48
ALA B  47
 None
 1.26A 3kw2B-5a7dB:
undetectable		 3kw2B-5a7dB:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5a7d PINS
(Drosophila
melanogaster) 		3 / 3 GLY B 225
THR B 227
ASN B 223
 None
 0.70A 3v4tD-5a7dB:
undetectable		 3v4tD-5a7dB:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.62A 3x2qC-5a7dL:
6.6
3x2qJ-5a7dL:
undetectable		 3x2qC-5a7dL:
19.25
3x2qJ-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.72A 3x2qP-5a7dL:
6.5
3x2qW-5a7dL:
undetectable		 3x2qP-5a7dL:
19.25
3x2qW-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 6 LEU L 446
ALA L 379
LEU L 374
SER L 370
 None
 0.93A 4d7bB-5a7dL:
undetectable		 4d7bB-5a7dL:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 6 LEU L 446
ALA L 379
LEU L 374
SER L 370
 None
 0.93A 4i89A-5a7dL:
undetectable		 4i89A-5a7dL:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 5a7d PINS
INSCUTEABLE
(Drosophila
melanogaster;
Drosophila
melanogaster) 		3 / 3 PRO L 309
ASN B 306
HIS B 321
 None
 0.89A 4ma3H-5a7dL:
undetectable
4ma3L-5a7dL:
undetectable		 4ma3H-5a7dL:
19.50
4ma3L-5a7dL:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 446
ALA L 379
LEU L 374
SER L 370
 None
 0.92A 4pwjB-5a7dL:
undetectable		 4pwjB-5a7dL:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 PHE L 468
ALA L 360
LEU L 403
PHE L 399
 None
 1.05A 4uymA-5a7dL:
undetectable		 4uymA-5a7dL:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 PHE L 468
ALA L 360
LEU L 403
PHE L 399
 None
 1.10A 4uymB-5a7dL:
1.3		 4uymB-5a7dL:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5a7d INSCUTEABLE
PINS
(Drosophila
melanogaster) 		4 / 7 ARG B 339
VAL L 310
TRP L 313
HIS B 324
 None
 1.11A 5ad9A-5a7dB:
undetectable
5ad9B-5a7dB:
undetectable		 5ad9A-5a7dB:
21.95
5ad9B-5a7dB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.78A 5b1bP-5a7dL:
6.6
5b1bW-5a7dL:
undetectable		 5b1bP-5a7dL:
19.25
5b1bW-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5a7d INSCUTEABLE
PINS
(Drosophila
melanogaster) 		3 / 3 ARG B 339
VAL L 310
TRP L 313
 None
 1.00A 5fvoA-5a7dB:
undetectable		 5fvoA-5a7dB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.67A 5z85C-5a7dL:
6.6
5z85J-5a7dL:
undetectable		 5z85C-5a7dL:
19.25
5z85J-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.68A 5zcoC-5a7dL:
6.6
5zcoJ-5a7dL:
undetectable		 5zcoC-5a7dL:
19.25
5zcoJ-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.70A 5zcqC-5a7dL:
6.6
5zcqJ-5a7dL:
undetectable		 5zcqC-5a7dL:
19.25
5zcqJ-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 7 LEU L 356
GLN L 357
PHE L 399
LEU L 403
 None
 0.65A 5zcqP-5a7dL:
6.6
5zcqW-5a7dL:
undetectable		 5zcqP-5a7dL:
19.25
5zcqW-5a7dL:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5a7d INSCUTEABLE
PINS
(Drosophila
melanogaster) 		5 / 10 SER B  40
GLY B  73
ILE L 334
ALA B  47
LEU B  46
 None
 1.47A 5zjiA-5a7dB:
3.2
5zjiJ-5a7dB:
undetectable		 5zjiA-5a7dB:
11.39
5zjiJ-5a7dB:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 5 PHE L 410
ASP L 412
HIS L 459
THR L 400
 None
 1.43A 6b58A-5a7dL:
2.8		 6b58A-5a7dL:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 5a7d PINS
(Drosophila
melanogaster) 		4 / 5 TYR B 360
GLN B 363
GLY B 305
ILE B 318
 None
 1.42A 6debB-5a7dB:
undetectable		 6debB-5a7dB:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a7d INSCUTEABLE
(Drosophila
melanogaster) 		4 / 5 ARG L 465
LEU L 461
PHE L 367
PHE L 468
 None
 1.42A 6nmpP-5a7dL:
6.6
6nmpW-5a7dL:
undetectable		 6nmpP-5a7dL:
19.25
6nmpW-5a7dL:
10.06