SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		5 / 9 THR A 108
GLY A  95
PHE A  97
LEU A  94
GLY A 180
 None
 1.33A 1jhyA-5a7tA:
undetectable		 1jhyA-5a7tA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		5 / 12 ILE A 179
GLY A 180
ASP A  93
ALA A 192
ILE A 182
 None
 1.03A 3jb1A-5a7tA:
undetectable		 3jb1A-5a7tA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		4 / 6 ASP A 220
ILE A 182
GLY A 180
VAL A 207
 None
 0.83A 3n3iA-5a7tA:
undetectable		 3n3iA-5a7tA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		4 / 8 ILE A 157
ASP A 159
VAL A 131
GLY A  95
 None
 0.78A 4acaC-5a7tA:
undetectable		 4acaC-5a7tA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		4 / 8 ILE A 157
ASP A 159
VAL A 131
GLY A  95
 None
 0.72A 4acbC-5a7tA:
undetectable		 4acbC-5a7tA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		4 / 4 VAL A  91
ILE A 229
ASN A 175
VAL A 156
 None
 1.28A 5ajqA-5a7tA:
undetectable		 5ajqA-5a7tA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		4 / 6 ARG A 206
PRO A 205
THR A 193
ILE A 157
 None
 1.28A 5ih0A-5a7tA:
undetectable		 5ih0A-5a7tA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		4 / 8 VAL A  91
ILE A 157
ALA A 197
LEU A 147
 None
None
None
PEG  A1248 (-4.9A)
 0.76A 5og9A-5a7tA:
undetectable		 5og9A-5a7tA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		5 / 12 PHE A 177
LEU A 158
VAL A 207
LEU A 226
ARG A 172
 None
 1.16A 5w7pA-5a7tA:
undetectable		 5w7pA-5a7tA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		3 / 3 LEU A 128
VAL A 112
ASP A 113
 None
 0.51A 5x23A-5a7tA:
undetectable		 5x23A-5a7tA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		3 / 3 ASP A 159
ARG A 187
ASP A  93
 None
 0.80A 5zvgA-5a7tA:
undetectable		 5zvgA-5a7tA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		3 / 3 ASP A 159
ARG A 187
ASP A  93
 None
 0.80A 5zvgB-5a7tA:
undetectable		 5zvgB-5a7tA:
22.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		8 / 12 LEU A 158
PRO A 160
ILE A 179
GLY A 180
ILE A 209
VAL A 218
ASP A 220
ILE A 225
 None
 0.39A 6emuB-5a7tA:
19.2		 6emuB-5a7tA:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE
(Sulfolobus
acidocaldarius) 		8 / 12 LEU A 158
PRO A 160
ILE A 179
GLY A 180
ILE A 209
VAL A 218
ASP A 220
ILE A 225
 None
 0.37A 6emuC-5a7tA:
19.1		 6emuC-5a7tA:
33.58