SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU B 254
LEU B 282
THR B 156
MET B 223
LEU B 251
 None
 1.19A 1tw4B-5a7vB:
undetectable		 1tw4B-5a7vB:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.84A 1v54C-5a7vB:
undetectable
1v54J-5a7vB:
undetectable		 1v54C-5a7vB:
20.78
1v54J-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.87A 1v54P-5a7vB:
undetectable
1v54W-5a7vB:
undetectable		 1v54P-5a7vB:
20.78
1v54W-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.83A 2dyrC-5a7vB:
undetectable
2dyrJ-5a7vB:
undetectable		 2dyrC-5a7vB:
20.78
2dyrJ-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.85A 2dyrP-5a7vB:
undetectable
2dyrW-5a7vB:
undetectable		 2dyrP-5a7vB:
20.78
2dyrW-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.87A 2eikP-5a7vB:
undetectable
2eikW-5a7vB:
undetectable		 2eikP-5a7vB:
20.78
2eikW-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.83A 2eilC-5a7vB:
undetectable
2eilJ-5a7vB:
undetectable		 2eilC-5a7vB:
20.78
2eilJ-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.82A 2eimP-5a7vB:
undetectable
2eimW-5a7vB:
undetectable		 2eimP-5a7vB:
20.78
2eimW-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG B  40
TYR B 358
GLY B 367
ILE B 114
 None
 0.94A 2f9wA-5a7vB:
undetectable
2f9wB-5a7vB:
undetectable		 2f9wA-5a7vB:
27.04
2f9wB-5a7vB:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_A_ADNA901_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		5 / 10 PHE B 116
HIS B 115
ASN B  45
ILE B  48
ALA B  44
 None
None
None
SO4  B1388 (-4.8A)
None
 1.34A 2gl0A-5a7vB:
undetectable
2gl0B-5a7vB:
undetectable		 2gl0A-5a7vB:
18.81
2gl0B-5a7vB:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE B 116
HIS B 115
ASN B  45
ILE B  48
ALA B  44
 None
None
None
SO4  B1388 (-4.8A)
None
 1.34A 2gl0D-5a7vB:
undetectable
2gl0E-5a7vB:
undetectable		 2gl0D-5a7vB:
18.81
2gl0E-5a7vB:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_E_ADNE905_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		5 / 11 PHE B 116
HIS B 115
ASN B  45
ILE B  48
ALA B  44
 None
None
None
SO4  B1388 (-4.8A)
None
 1.31A 2gl0E-5a7vB:
undetectable
2gl0F-5a7vB:
undetectable		 2gl0E-5a7vB:
18.81
2gl0F-5a7vB:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR B 297
GLY B 293
PHE B 262
 None
 0.71A 2m2pB-5a7vB:
undetectable		 2m2pB-5a7vB:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE B 344
ILE B  98
GLU B 227
SER B 200
ASP B 142
 MAN  B1386 ( 4.1A)
MAN  B1386 ( 4.9A)
MAN  B1386 (-3.7A)
MAN  B1386 ( 4.3A)
MAN  B1386 (-3.1A)
 1.42A 2pgfA-5a7vB:
undetectable		 2pgfA-5a7vB:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 5 ALA B 184
GLY B 197
CYH B 198
LYS B 199
 None
None
None
MAN  B1485 ( 2.8A)
 1.41A 2ylgA-5a7vB:
undetectable		 2ylgA-5a7vB:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.90A 3asnP-5a7vB:
undetectable
3asnW-5a7vB:
undetectable		 3asnP-5a7vB:
20.78
3asnW-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.89A 3asoP-5a7vB:
undetectable
3asoW-5a7vB:
undetectable		 3asoP-5a7vB:
20.78
3asoW-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 5 PRO B 272
THR B 342
VAL B 343
GLY B 360
 None
 1.11A 3elzA-5a7vB:
0.5		 3elzA-5a7vB:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		3 / 3 CYH B 140
PRO B 122
ASP B 127
 None
 1.00A 3hlwB-5a7vB:
undetectable		 3hlwB-5a7vB:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 8 ILE B 345
TRP B  33
GLY B  37
ASN B  28
 None
 0.98A 4fgjA-5a7vB:
undetectable
4fgjB-5a7vB:
undetectable		 4fgjA-5a7vB:
19.79
4fgjB-5a7vB:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY B 367
ASN B  45
PRO B  75
ILE B  48
 None
None
None
SO4  B1388 (-4.8A)
 0.94A 4j4vC-5a7vB:
undetectable		 4j4vC-5a7vB:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 6 THR B 148
GLU B 150
HIS B 181
LEU B 238
 None
 1.14A 4pgfA-5a7vB:
undetectable		 4pgfA-5a7vB:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 4 VAL B 123
GLU B 119
GLY B 106
LEU B  87
 None
 1.12A 5g5gC-5a7vB:
undetectable		 5g5gC-5a7vB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 5 ALA B 184
GLY B 197
CYH B 198
LYS B 199
 None
None
None
MAN  B1485 ( 2.8A)
 1.43A 5jliA-5a7vB:
undetectable		 5jliA-5a7vB:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 5 ALA B 184
GLY B 197
CYH B 198
LYS B 199
 None
None
None
MAN  B1485 ( 2.8A)
 1.49A 5jt4A-5a7vB:
undetectable		 5jt4A-5a7vB:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		3 / 3 SER B 200
SER B 202
PHE B 344
 MAN  B1386 ( 4.3A)
None
MAN  B1386 ( 4.1A)
 0.90A 5mugA-5a7vB:
undetectable		 5mugA-5a7vB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 6 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.86A 5x19P-5a7vB:
undetectable		 5x19P-5a7vB:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS B 253
LEU B 254
PHE B 317
PHE B 309
 None
 0.84A 5x1fP-5a7vB:
undetectable
5x1fW-5a7vB:
undetectable		 5x1fP-5a7vB:
20.78
5x1fW-5a7vB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE B 222
SER B 202
LEU B 167
LEU B 254
LEU B 282
 None
 1.45A 5y2oA-5a7vB:
undetectable		 5y2oA-5a7vB:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE B 116
VAL B 123
PRO B  75
VAL B  47
 None
 1.29A 6ekzA-5a7vB:
undetectable		 6ekzA-5a7vB:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU B 266
GLN B 265
LYS B 199
 None
None
MAN  B1485 ( 2.8A)
 0.86A 6exiB-5a7vB:
undetectable		 6exiB-5a7vB:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU B 266
GLN B 265
LYS B 199
 None
None
MAN  B1485 ( 2.8A)
 0.81A 6exiA-5a7vB:
undetectable		 6exiA-5a7vB:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 4 LEU B 105
ASP B 142
PRO B 143
ARG B  89
 None
MAN  B1386 (-3.1A)
None
MAN  B1485 ( 2.7A)
 1.10A 6fgdA-5a7vB:
undetectable		 6fgdA-5a7vB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS B 115
VAL B  47
SER B 111
LYS B  83
 None
 0.97A 6hu9S-5a7vB:
undetectable
6hu9q-5a7vB:
undetectable		 6hu9S-5a7vB:
14.79
6hu9q-5a7vB:
17.63