SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 8 HIS A 114
CYH A 198
GLY A 197
GLY A 239
TYR A 195
 ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
None
None
None
 1.43A 1ekjA-5a87A:
undetectable
1ekjB-5a87A:
undetectable		 1ekjA-5a87A:
21.89
1ekjB-5a87A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 8 HIS A 114
CYH A 198
GLY A 197
GLY A 239
TYR A 195
 ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
None
None
None
 1.42A 1ekjG-5a87A:
undetectable
1ekjH-5a87A:
undetectable		 1ekjG-5a87A:
21.89
1ekjH-5a87A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 10 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.96A 1t3rA-5a87A:
undetectable		 1t3rA-5a87A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 10 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.99A 1t7iA-5a87A:
undetectable		 1t7iA-5a87A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_1
(PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 12 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.95A 2o4nA-5a87A:
undetectable		 2o4nA-5a87A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 11 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.85A 2o4pA-5a87A:
undetectable		 2o4pA-5a87A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 10 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.81A 3el5A-5a87A:
undetectable		 3el5A-5a87A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		4 / 6 LEU A  80
VAL A 236
VAL A 188
ILE A  49
 None
 1.22A 3k5vA-5a87A:
undetectable		 3k5vA-5a87A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 10 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.95A 3lzvA-5a87A:
undetectable		 3lzvA-5a87A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 10 LEU A  96
ALA A  86
VAL A  44
ILE A  83
LEU A  95
 None
 1.00A 3ogqA-5a87A:
undetectable		 3ogqA-5a87A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		4 / 5 ASN A 183
ASP A  84
THR A 133
SER A 180
 None
 1.42A 3p2kC-5a87A:
undetectable		 3p2kC-5a87A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 11 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 1.03A 3spkA-5a87A:
undetectable		 3spkA-5a87A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 12 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 1.03A 3spkB-5a87A:
undetectable		 3spkB-5a87A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_C_T1CC401_1
(TETX2 PROTEIN)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 11 ASP A 247
ASN A  70
GLY A 197
PRO A 243
GLY A 245
 None
 1.43A 3v3oC-5a87A:
undetectable		 3v3oC-5a87A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		4 / 5 ASP A 117
GLU A 146
GLY A 147
GLU A 149
 GOL  A1266 (-3.0A)
None
None
None
 1.43A 3w9tA-5a87A:
undetectable		 3w9tA-5a87A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		4 / 5 ASP A 117
GLU A 146
GLY A 147
GLU A 149
 GOL  A1266 (-3.0A)
None
None
None
 1.43A 3w9tC-5a87A:
undetectable		 3w9tC-5a87A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		4 / 5 ASP A 117
GLU A 146
GLY A 147
GLU A 149
 GOL  A1266 (-3.0A)
None
None
None
 1.42A 3w9tD-5a87A:
undetectable		 3w9tD-5a87A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		4 / 5 ASP A 117
GLU A 146
GLY A 147
GLU A 149
 GOL  A1266 (-3.0A)
None
None
None
 1.42A 3w9tG-5a87A:
undetectable		 3w9tG-5a87A:
21.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1D_A_X8ZA350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		8 / 9 TYR A  67
TRP A  87
HIS A 116
ASP A 118
HIS A 179
CYH A 198
ASN A 210
HIS A 240
 GOL  A1262 ( 4.7A)
GOL  A1262 ( 4.8A)
ZN  A1263 (-3.0A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
GOL  A1262 (-4.1A)
ZN  A1265 ( 3.3A)
 0.45A 4c1dA-5a87A:
44.7		 4c1dA-5a87A:
90.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		9 / 10 TYR A  67
TRP A  87
HIS A 114
HIS A 116
ASP A 118
HIS A 179
CYH A 198
ASN A 210
HIS A 240
 GOL  A1262 ( 4.7A)
GOL  A1262 ( 4.8A)
ZN  A1263 (-3.2A)
ZN  A1263 (-3.0A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
GOL  A1262 (-4.1A)
ZN  A1265 ( 3.3A)
 0.35A 4c1dB-5a87A:
44.8		 4c1dB-5a87A:
90.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		6 / 11 HIS A 114
HIS A 116
ASP A 118
HIS A 179
CYH A 198
HIS A 240
 ZN  A1263 (-3.2A)
ZN  A1263 (-3.0A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
ZN  A1265 ( 3.3A)
 0.33A 4c1fA-5a87A:
32.6
4c1fB-5a87A:
31.5		 4c1fA-5a87A:
30.12
4c1fB-5a87A:
30.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		7 / 9 HIS A 114
HIS A 116
ASP A 118
HIS A 179
CYH A 198
GLY A 209
HIS A 240
 ZN  A1263 (-3.2A)
ZN  A1263 (-3.0A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
None
ZN  A1265 ( 3.3A)
 0.36A 4c1hA-5a87A:
33.1		 4c1hA-5a87A:
37.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		7 / 9 TRP A  87
HIS A 114
ASP A 118
HIS A 179
CYH A 198
GLY A 209
HIS A 240
 GOL  A1262 ( 4.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
None
ZN  A1265 ( 3.3A)
 0.84A 4c1hA-5a87A:
33.1		 4c1hA-5a87A:
37.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EXS_A_X8ZA301_1
(BETA-LACTAMASE NDM-1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 9 HIS A 116
ASP A 118
HIS A 179
CYH A 198
HIS A 240
 ZN  A1263 (-3.0A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
ZN  A1265 ( 3.3A)
 0.24A 4exsA-5a87A:
32.8		 4exsA-5a87A:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EXS_A_X8ZA301_1
(BETA-LACTAMASE NDM-1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 9 TRP A  87
ASP A 118
HIS A 179
CYH A 198
HIS A 240
 GOL  A1262 ( 4.8A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
ZN  A1265 ( 3.3A)
 0.97A 4exsA-5a87A:
32.8		 4exsA-5a87A:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		6 / 8 HIS A 116
ASP A 118
HIS A 179
CYH A 198
ASN A 210
HIS A 240
 ZN  A1263 (-3.0A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
GOL  A1262 (-4.1A)
ZN  A1265 ( 3.3A)
 0.48A 4exsB-5a87A:
33.2		 4exsB-5a87A:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 8 TRP A  87
ASP A 118
HIS A 179
CYH A 198
HIS A 240
 GOL  A1262 ( 4.8A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
ZN  A1265 ( 3.3A)
 0.99A 4exsB-5a87A:
33.2		 4exsB-5a87A:
36.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 12 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.86A 4njuA-5a87A:
undetectable		 4njuA-5a87A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 12 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.88A 4njuC-5a87A:
undetectable		 4njuC-5a87A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 12 LEU A 172
ARG A 166
ILE A  83
VAL A  74
LEU A  81
 None
 1.01A 4o1zB-5a87A:
undetectable		 4o1zB-5a87A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 11 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.90A 4qgiB-5a87A:
undetectable		 4qgiB-5a87A:
17.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		6 / 8 HIS A 116
ASP A 118
HIS A 179
CYH A 198
ASN A 210
HIS A 240
 ZN  A1263 (-3.0A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
GOL  A1262 (-4.1A)
ZN  A1265 ( 3.3A)
 0.33A 5a5zA-5a87A:
33.3		 5a5zA-5a87A:
35.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 8 TRP A  87
ASP A 118
HIS A 179
CYH A 198
HIS A 240
 GOL  A1262 ( 4.8A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
ZN  A1265 ( 3.3A)
 1.03A 5a5zA-5a87A:
33.3		 5a5zA-5a87A:
35.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 7 HIS A 179
CYH A 198
GLY A 209
ASN A 210
HIS A 240
 ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
None
GOL  A1262 (-4.1A)
ZN  A1265 ( 3.3A)
 0.41A 5a5zC-5a87A:
33.3		 5a5zC-5a87A:
35.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 11 HIS A 114
HIS A 116
ASP A 118
HIS A 179
HIS A 240
 ZN  A1263 (-3.2A)
ZN  A1263 (-3.0A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 ( 3.3A)
 0.77A 5ayaA-5a87A:
18.5		 5ayaA-5a87A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		4 / 7 ASP A 118
ASP A  84
TYR A 195
GLY A 239
 ZN  A1265 (-2.8A)
None
None
None
 1.03A 5hwaA-5a87A:
undetectable		 5hwaA-5a87A:
21.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		3 / 3 HIS A 251
ASN A 254
ALA A 258
 None
 0.18A 5n4tB-5a87A:
42.9		 5n4tB-5a87A:
93.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		4 / 5 VAL A 186
HIS A 114
LEU A 158
ASP A  84
 None
ZN  A1263 (-3.2A)
None
None
 1.45A 5vcvA-5a87A:
undetectable		 5vcvA-5a87A:
23.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		6 / 8 HIS A 116
ASP A 118
HIS A 179
CYH A 198
ASN A 210
HIS A 240
 ZN  A1263 (-3.0A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
GOL  A1262 (-4.1A)
ZN  A1265 ( 3.3A)
 0.45A 5zj8A-5a87A:
17.0		 5zj8A-5a87A:
36.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		6 / 8 TRP A  87
ASP A 118
HIS A 179
CYH A 198
ASN A 210
HIS A 240
 GOL  A1262 ( 4.8A)
ZN  A1265 (-2.8A)
ZN  A1263 (-3.2A)
ZN  A1265 (-2.2A)
GOL  A1262 (-4.1A)
ZN  A1265 ( 3.3A)
 1.00A 5zj8A-5a87A:
17.0		 5zj8A-5a87A:
36.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 12 LEU A  96
ALA A  86
ILE A  57
GLY A  71
ILE A  83
 None
 0.82A 6dilA-5a87A:
undetectable		 6dilA-5a87A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		3 / 3 SER A 136
SER A 138
ALA A 177
 GOL  A1264 (-2.5A)
GOL  A1264 ( 4.3A)
None
 0.73A 6dwnC-5a87A:
undetectable		 6dwnC-5a87A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5a87 METALLO-BETA-LACTAMA
SE VIM-5
(Klebsiella
pneumoniae) 		5 / 9 LEU A  72
ILE A  49
PRO A 243
VAL A 235
ILE A 237
 None
 1.13A 6ef6A-5a87A:
undetectable		 6ef6A-5a87A:
23.45