SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a8q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 6 PRO A 105
ASP A 333
ASP A 335
TRP A 336
 None
None
None
BGC  A1368 (-3.8A)
 1.50A 1hpkA-5a8qA:
undetectable		 1hpkA-5a8qA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 12 LEU A 137
ALA A 130
LEU A 133
MET A 340
ILE A  73
 None
 1.03A 1mx8A-5a8qA:
undetectable		 1mx8A-5a8qA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 ASP A 333
ASP A 335
TRP A 336
HIS A 107
 None
None
BGC  A1368 (-3.8A)
BGC  A1368 (-3.9A)
 1.18A 1pk2A-5a8qA:
undetectable		 1pk2A-5a8qA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 1v54A-5a8qA:
undetectable
1v54C-5a8qA:
undetectable		 1v54A-5a8qA:
22.09
1v54C-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.97A 1v54N-5a8qA:
undetectable
1v54P-5a8qA:
undetectable		 1v54N-5a8qA:
22.09
1v54P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.06A 1v55A-5a8qA:
undetectable
1v55C-5a8qA:
undetectable		 1v55A-5a8qA:
22.09
1v55C-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 2dyrA-5a8qA:
undetectable
2dyrC-5a8qA:
undetectable		 2dyrA-5a8qA:
22.09
2dyrC-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.01A 2dyrN-5a8qA:
undetectable
2dyrP-5a8qA:
undetectable		 2dyrN-5a8qA:
22.09
2dyrP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.05A 2eijA-5a8qA:
undetectable
2eijC-5a8qA:
undetectable		 2eijA-5a8qA:
22.09
2eijC-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 2eijN-5a8qA:
undetectable
2eijP-5a8qA:
undetectable		 2eijN-5a8qA:
22.09
2eijP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.07A 2eikA-5a8qA:
undetectable
2eikC-5a8qA:
undetectable		 2eikA-5a8qA:
22.09
2eikC-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 2eikN-5a8qA:
undetectable
2eikP-5a8qA:
undetectable		 2eikN-5a8qA:
22.09
2eikP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 2eilA-5a8qA:
undetectable
2eilC-5a8qA:
undetectable		 2eilA-5a8qA:
22.09
2eilC-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.00A 2eilN-5a8qA:
undetectable
2eilP-5a8qA:
undetectable		 2eilN-5a8qA:
22.09
2eilP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.99A 2y69A-5a8qA:
undetectable
2y69C-5a8qA:
undetectable		 2y69A-5a8qA:
22.09
2y69C-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 2y69C-5a8qA:
undetectable
2y69N-5a8qA:
undetectable
2y69P-5a8qA:
undetectable		 2y69C-5a8qA:
18.73
2y69N-5a8qA:
22.09
2y69P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.06A 3abkA-5a8qA:
undetectable
3abkC-5a8qA:
undetectable		 3abkA-5a8qA:
22.09
3abkC-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 3abkN-5a8qA:
undetectable
3abkP-5a8qA:
undetectable		 3abkN-5a8qA:
22.09
3abkP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.01A 3ablA-5a8qA:
undetectable
3ablC-5a8qA:
undetectable
3ablP-5a8qA:
undetectable		 3ablA-5a8qA:
22.09
3ablC-5a8qA:
18.73
3ablP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.96A 3ablC-5a8qA:
undetectable
3ablN-5a8qA:
undetectable
3ablP-5a8qA:
undetectable		 3ablC-5a8qA:
18.73
3ablN-5a8qA:
22.09
3ablP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 3abmA-5a8qA:
undetectable
3abmC-5a8qA:
undetectable
3abmP-5a8qA:
undetectable		 3abmA-5a8qA:
22.09
3abmC-5a8qA:
18.73
3abmP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 3abmN-5a8qA:
undetectable
3abmP-5a8qA:
undetectable		 3abmN-5a8qA:
22.09
3abmP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.06A 3ag2A-5a8qA:
undetectable
3ag2C-5a8qA:
undetectable		 3ag2A-5a8qA:
22.09
3ag2C-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 3ag2N-5a8qA:
undetectable
3ag2P-5a8qA:
undetectable		 3ag2N-5a8qA:
22.09
3ag2P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.06A 3ag3A-5a8qA:
undetectable
3ag3C-5a8qA:
undetectable		 3ag3A-5a8qA:
22.09
3ag3C-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 3ag3N-5a8qA:
undetectable
3ag3P-5a8qA:
undetectable		 3ag3N-5a8qA:
22.09
3ag3P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.05A 3ag4A-5a8qA:
undetectable
3ag4C-5a8qA:
undetectable		 3ag4A-5a8qA:
22.09
3ag4C-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.01A 3ag4N-5a8qA:
undetectable
3ag4P-5a8qA:
undetectable		 3ag4N-5a8qA:
22.09
3ag4P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.01A 3asnC-5a8qA:
undetectable
3asnN-5a8qA:
undetectable
3asnP-5a8qA:
undetectable		 3asnC-5a8qA:
18.73
3asnN-5a8qA:
22.09
3asnP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.00A 3asoA-5a8qA:
undetectable
3asoC-5a8qA:
undetectable
3asoP-5a8qA:
undetectable		 3asoA-5a8qA:
22.09
3asoC-5a8qA:
18.73
3asoP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.99A 3asoC-5a8qA:
undetectable
3asoN-5a8qA:
undetectable
3asoP-5a8qA:
undetectable		 3asoC-5a8qA:
18.73
3asoN-5a8qA:
22.09
3asoP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		3 / 3 TYR A 119
TYR A 175
ILE A 171
 None
 0.80A 3eteA-5a8qA:
undetectable
3eteB-5a8qA:
undetectable		 3eteA-5a8qA:
20.69
3eteB-5a8qA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 12 ILE A 244
ALA A 281
ALA A 228
VAL A 227
PRO A 225
 None
 0.92A 3jb2A-5a8qA:
undetectable		 3jb2A-5a8qA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 12 ILE A 244
ALA A 281
ALA A 228
VAL A 227
PRO A 225
 None
 0.85A 3jb3A-5a8qA:
undetectable		 3jb3A-5a8qA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 11 ALA A 250
LEU A 226
LEU A 186
GLY A 229
LEU A 236
 None
 1.29A 3uudA-5a8qA:
undetectable		 3uudA-5a8qA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 12 THR A 328
GLN A 351
PHE A 332
ASN A  72
GLY A  98
 None
 1.25A 3v3oA-5a8qA:
undetectable		 3v3oA-5a8qA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 12 THR A 328
PHE A 332
ASN A  72
ALA A  94
ASN A  95
 None
 1.19A 3v3oA-5a8qA:
undetectable		 3v3oA-5a8qA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 12 THR A 328
PHE A 332
ASN A  72
GLY A  98
ASN A  96
 None
 1.20A 3v3oA-5a8qA:
undetectable		 3v3oA-5a8qA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.99A 3wg7A-5a8qA:
undetectable
3wg7C-5a8qA:
undetectable
3wg7P-5a8qA:
undetectable		 3wg7A-5a8qA:
22.09
3wg7C-5a8qA:
18.73
3wg7P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.97A 3wg7C-5a8qA:
undetectable
3wg7N-5a8qA:
undetectable
3wg7P-5a8qA:
undetectable		 3wg7C-5a8qA:
18.73
3wg7N-5a8qA:
22.09
3wg7P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.01A 3x2qA-5a8qA:
undetectable
3x2qC-5a8qA:
undetectable
3x2qP-5a8qA:
undetectable		 3x2qA-5a8qA:
22.09
3x2qC-5a8qA:
18.73
3x2qP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 3x2qC-5a8qA:
undetectable
3x2qN-5a8qA:
undetectable
3x2qP-5a8qA:
undetectable		 3x2qC-5a8qA:
18.73
3x2qN-5a8qA:
22.09
3x2qP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 5 ASP A 132
LEU A 133
GLU A  91
LYS A  87
 None
 1.43A 4a3pA-5a8qA:
undetectable		 4a3pA-5a8qA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 4 ASN A  72
SER A  88
LEU A  89
THR A 328
 None
 1.06A 4an2A-5a8qA:
undetectable		 4an2A-5a8qA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 5 ASN A 188
HIS A 142
GLU A 185
THR A 290
 BGC  A1367 (-3.8A)
BGC  A1367 (-4.0A)
None
None
 1.44A 4p6sA-5a8qA:
undetectable		 4p6sA-5a8qA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 ASN A 231
TYR A 256
TYR A 312
PHE A 271
 None
BGC  A1367 (-4.6A)
None
None
 1.21A 4yv5A-5a8qA:
undetectable		 4yv5A-5a8qA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 ASN A 231
TYR A 256
TYR A 312
PHE A 271
 None
BGC  A1367 (-4.6A)
None
None
 1.19A 4yv5B-5a8qA:
undetectable		 4yv5B-5a8qA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.99A 5b1aA-5a8qA:
undetectable
5b1aC-5a8qA:
undetectable
5b1aP-5a8qA:
undetectable		 5b1aA-5a8qA:
22.09
5b1aC-5a8qA:
18.73
5b1aP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.99A 5b1aN-5a8qA:
undetectable
5b1aP-5a8qA:
undetectable		 5b1aN-5a8qA:
22.09
5b1aP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.04A 5b1bA-5a8qA:
undetectable
5b1bC-5a8qA:
undetectable
5b1bP-5a8qA:
undetectable		 5b1bA-5a8qA:
22.09
5b1bC-5a8qA:
18.73
5b1bP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.05A 5b1bN-5a8qA:
undetectable
5b1bP-5a8qA:
undetectable		 5b1bN-5a8qA:
22.09
5b1bP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.04A 5b3sA-5a8qA:
undetectable
5b3sC-5a8qA:
undetectable
5b3sP-5a8qA:
undetectable		 5b3sA-5a8qA:
22.09
5b3sC-5a8qA:
18.73
5b3sP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 5b3sN-5a8qA:
undetectable
5b3sP-5a8qA:
undetectable		 5b3sN-5a8qA:
22.09
5b3sP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 12 ILE A 135
PHE A  68
ALA A 182
ILE A  73
PHE A 332
 None
 1.16A 5ih0A-5a8qA:
undetectable		 5ih0A-5a8qA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 5iy5A-5a8qA:
undetectable
5iy5C-5a8qA:
undetectable		 5iy5A-5a8qA:
22.09
5iy5C-5a8qA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.01A 5iy5C-5a8qA:
undetectable
5iy5N-5a8qA:
undetectable
5iy5P-5a8qA:
undetectable		 5iy5C-5a8qA:
18.47
5iy5N-5a8qA:
22.09
5iy5P-5a8qA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 12 ILE A 224
PHE A  50
SER A  52
TYR A 217
ILE A 216
 None
 1.18A 5n0sB-5a8qA:
undetectable		 5n0sB-5a8qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.00A 5w97A-5a8qA:
undetectable
5w97C-5a8qA:
undetectable
5w97c-5a8qA:
undetectable		 5w97A-5a8qA:
22.09
5w97C-5a8qA:
18.73
5w97c-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 5wauA-5a8qA:
undetectable
5wauC-5a8qA:
undetectable
5wauc-5a8qA:
undetectable		 5wauA-5a8qA:
22.09
5wauC-5a8qA:
18.73
5wauc-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.05A 5x19A-5a8qA:
undetectable
5x19C-5a8qA:
undetectable
5x19P-5a8qA:
undetectable		 5x19A-5a8qA:
22.09
5x19C-5a8qA:
18.73
5x19P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.07A 5x1fN-5a8qA:
undetectable
5x1fP-5a8qA:
undetectable		 5x1fN-5a8qA:
22.09
5x1fP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.98A 5xdqA-5a8qA:
undetectable
5xdqC-5a8qA:
undetectable
5xdqP-5a8qA:
undetectable		 5xdqA-5a8qA:
22.09
5xdqC-5a8qA:
18.73
5xdqP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.99A 5xdqC-5a8qA:
undetectable
5xdqN-5a8qA:
undetectable
5xdqP-5a8qA:
undetectable		 5xdqC-5a8qA:
18.73
5xdqN-5a8qA:
22.09
5xdqP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 5xdxC-5a8qA:
undetectable
5xdxN-5a8qA:
undetectable
5xdxP-5a8qA:
undetectable		 5xdxC-5a8qA:
18.47
5xdxN-5a8qA:
22.09
5xdxP-5a8qA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		3 / 3 THR A 290
GLU A 185
HIS A 142
 None
None
BGC  A1367 (-4.0A)
 0.88A 5xiqB-5a8qA:
undetectable		 5xiqB-5a8qA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		3 / 3 THR A 290
GLU A 185
HIS A 142
 None
None
BGC  A1367 (-4.0A)
 0.90A 5xiqD-5a8qA:
undetectable		 5xiqD-5a8qA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 5 HIS A 303
SER A 337
TYR A 300
GLY A 301
 BGC  A1366 ( 3.7A)
BGC  A1368 (-3.5A)
None
None
 0.83A 5yodH-5a8qA:
undetectable		 5yodH-5a8qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 5z84A-5a8qA:
undetectable
5z84C-5a8qA:
undetectable
5z84P-5a8qA:
undetectable		 5z84A-5a8qA:
22.09
5z84C-5a8qA:
18.73
5z84P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 5z85A-5a8qA:
undetectable
5z85C-5a8qA:
undetectable
5z85P-5a8qA:
undetectable		 5z85A-5a8qA:
22.09
5z85C-5a8qA:
18.73
5z85P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.01A 5z86A-5a8qA:
undetectable
5z86C-5a8qA:
undetectable
5z86P-5a8qA:
undetectable		 5z86A-5a8qA:
22.09
5z86C-5a8qA:
18.73
5z86P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.00A 5z86C-5a8qA:
undetectable
5z86N-5a8qA:
undetectable
5z86P-5a8qA:
undetectable		 5z86C-5a8qA:
18.73
5z86N-5a8qA:
22.09
5z86P-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 5zcoA-5a8qA:
undetectable
5zcoC-5a8qA:
undetectable
5zcoP-5a8qA:
undetectable		 5zcoA-5a8qA:
22.09
5zcoC-5a8qA:
18.73
5zcoP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 5zcoC-5a8qA:
undetectable
5zcoN-5a8qA:
undetectable
5zcoP-5a8qA:
undetectable		 5zcoC-5a8qA:
18.73
5zcoN-5a8qA:
22.09
5zcoP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 5zcpA-5a8qA:
undetectable
5zcpC-5a8qA:
undetectable
5zcpP-5a8qA:
undetectable		 5zcpA-5a8qA:
22.09
5zcpC-5a8qA:
18.73
5zcpP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 5zcpC-5a8qA:
undetectable
5zcpN-5a8qA:
undetectable
5zcpP-5a8qA:
undetectable		 5zcpC-5a8qA:
18.73
5zcpN-5a8qA:
22.09
5zcpP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.02A 5zcqA-5a8qA:
undetectable
5zcqC-5a8qA:
undetectable
5zcqP-5a8qA:
undetectable		 5zcqA-5a8qA:
22.09
5zcqC-5a8qA:
18.73
5zcqP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.03A 5zcqN-5a8qA:
undetectable
5zcqP-5a8qA:
undetectable		 5zcqN-5a8qA:
22.09
5zcqP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 5 ASP A 124
ILE A 106
PHE A 167
ASN A 177
 None
 1.10A 6a93B-5a8qA:
undetectable		 6a93B-5a8qA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 6 LEU A 197
THR A 196
GLY A 194
ARG A 200
 None
None
GXT  A1374 (-3.3A)
GXT  A1374 ( 3.1A)
 1.04A 6gtqB-5a8qA:
undetectable
6gtqD-5a8qA:
undetectable		 6gtqB-5a8qA:
19.94
6gtqD-5a8qA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 10 ALA A 289
PHE A  58
ILE A 224
ALA A 182
LEU A 226
 None
 1.18A 6h1lA-5a8qA:
undetectable		 6h1lA-5a8qA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		5 / 11 ALA A 289
PHE A  58
ILE A 224
ALA A 182
LEU A 226
 None
 1.28A 6h1lB-5a8qA:
undetectable		 6h1lB-5a8qA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 8 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 1.01A 6nknC-5a8qA:
undetectable
6nknN-5a8qA:
undetectable
6nknP-5a8qA:
undetectable		 6nknC-5a8qA:
18.73
6nknN-5a8qA:
22.09
6nknP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.97A 6nmfN-5a8qA:
undetectable
6nmfP-5a8qA:
undetectable		 6nmfN-5a8qA:
22.09
6nmfP-5a8qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a8q PUTATIVE RETAINING
B-GLYCOSIDASE
(Saccharophagus
degradans) 		4 / 7 TRP A  85
ASP A 117
TYR A 119
TRP A 129
 None
None
None
SO4  A1371 (-4.0A)
 0.97A 6nmpN-5a8qA:
undetectable
6nmpP-5a8qA:
undetectable		 6nmpN-5a8qA:
22.09
6nmpP-5a8qA:
18.73