SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a8v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5a8v POLYHEDRIN
(Cypovirus
5) 		5 / 12 LEU A 125
TRP A  48
GLY A  56
SER A  57
ILE A 190
 None
 1.10A 1kyvD-5a8vA:
undetectable
1kyvE-5a8vA:
undetectable		 1kyvD-5a8vA:
21.40
1kyvE-5a8vA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5a8v POLYHEDRIN
(Cypovirus
5) 		4 / 8 ASN A  47
PHE A 223
TYR A 245
ASN A  70
 None
 1.14A 2wekA-5a8vA:
undetectable		 2wekA-5a8vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5a8v POLYHEDRIN
(Cypovirus
5) 		4 / 8 ASN A  47
PHE A 223
TYR A 245
ASN A  70
 None
 1.13A 2wekB-5a8vA:
undetectable		 2wekB-5a8vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5a8v POLYHEDRIN
(Cypovirus
5) 		4 / 4 VAL A 114
PHE A 192
PHE A 127
VAL A 177
 None
 1.47A 3rv5C-5a8vA:
undetectable
3rv5D-5a8vA:
undetectable		 3rv5C-5a8vA:
17.70
3rv5D-5a8vA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5a8v POLYHEDRIN
(Cypovirus
5) 		4 / 5 GLN A  61
LEU A  62
ASP A 106
ASP A 101
 None
 1.15A 4qtuD-5a8vA:
undetectable		 4qtuD-5a8vA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5a8v POLYHEDRIN
(Cypovirus
5) 		5 / 12 ASN A 229
VAL A  42
ILE A 113
SER A 174
GLN A 162
 None
 1.41A 4xueA-5a8vA:
undetectable		 4xueA-5a8vA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5a8v POLYHEDRIN
(Cypovirus
5) 		4 / 5 THR A  33
ASN A  31
TRP A  48
LEU A  58
 None
 1.32A 5vkqA-5a8vA:
undetectable
5vkqB-5a8vA:
undetectable		 5vkqA-5a8vA:
9.41
5vkqB-5a8vA:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5a8v POLYHEDRIN
(Cypovirus
5) 		4 / 5 THR A  33
ASN A  31
TRP A  48
LEU A  58
 None
 1.35A 5vkqB-5a8vA:
undetectable
5vkqC-5a8vA:
undetectable		 5vkqB-5a8vA:
9.41
5vkqC-5a8vA:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5a8v POLYHEDRIN
(Cypovirus
5) 		4 / 5 THR A  33
ASN A  31
TRP A  48
LEU A  58
 None
 1.34A 5vkqC-5a8vA:
undetectable
5vkqD-5a8vA:
undetectable		 5vkqC-5a8vA:
9.41
5vkqD-5a8vA:
9.41